Ammonium silicofluoride

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· Do not touch damaged containers or spilled material unless wearing appropriate protective clothing.

INHALATION: remove patient to fresh air.

General First Aid:

General First Aid:

· Wear positive pressure self-contained breathing apparatus (SCBA).

· Wear positive pressure self-contained breathing apparatus (SCBA).

Biological Exposure Indices (BEI) [ACGIH] - Fluorides in urine = 2 mg/L prior to shift or 3 mg/L at end of shift; (Repeated measurements recommended.)

1.0 [mg/m3], inhalable fraction, as F[German Research Foundation (DFG)]

Environmental considerations- land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner./ Cover solids with a plastic sheet to prevent dissolving in rain or fire fighting water.

Environmental considerations- water spill: Use natural deep water pockets, excavated lagoons, or sand bag barriers to trap material at bottom. Remove trapped material with suction hoses.

Environmental considerations- air spill: Vapor knockdown water is corrosive or toxic and should be diked for containment.

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

If material not involved in fire: Keep material out of water sources and sewers. Build dikes to contain flow as necessary.

Keep upwind. Avoid breathing vapors or dusts. Wash away any material which may have contacted the body with copious amt of water or soap and water.

SRP: Contaminated protective clothing should be segregated in such a manner so that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. Quality assurance to ascertain the completeness of the cleaning procedures should be implemented before the decontaminated protective clothing is returned for reuse by the workers.

SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.

Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]:

Immediate precautionary measure

Immediate precautionary measure

2.5 [mg/m3], as F

8 hr Time Weighted Avg (TWA): 2.5 mg/cu m. /Fluorides, as F/

Excursion Limit Recommendation: Excursions in worker exposure levels may exceed 3 times the TLV-TWA for no more than a total of 30 minutes during a work day, and under no circumstances should they exceed 5 times the TLV-TWA, provided that the TLV-TWA is not exceeded. /Fluorides, as F/

A4; Not classifiable as a human carcinogen. /Fluorides, as F/

Biological Exposure Index (BEI): Determinant: fluorides in urine; Sampling Time: prior to shift; BEI: 3 mg/g creatinine. Determinant: fluorides in urine; Sampling Time: end of shift; BEI: 10 mg/g creatinine. The determinant may be present in biological specimens collected from subjects who have not been occupationally exposed, at a concentration which could affect interpretation of the result. Such background concentrations are incorporated in the BEI value. The determinant is nonspecific, since it is also observed after exposure to other chemicals. /Fluorides/

SYMPTOMATOLOGY: A. Ingestion of soluble fluoride salts. 1. Salty or soapy taste, salivation, nausea. Repeated small doses (as in drinking water) may produce no other symptoms, but polyuria and polydipsia have also been reported. 2. Large doses lead promptly to burning or crampy abdominal pain, intense vomiting and diarrhea, often with hematemesis and melena. Dehydration and thirst. 3. Muscle weakness, tremors, and rarely transient epileptiform convulsions, preceded or followed by progressive central nervous depression (lethargy, coma and respiratory arrest, even in the absence of circulatory failure). 4. Shock characterized by pallor, weak and thready pulse (sometimes irregular), shallow unlabored respiration, weak heart sounds, wet cold skin, cyanosis, anuria, dilated pupils, followed almost invariably by death in 2 to 4 hours. 5. Even in the absence of shock, arrhythmias may occur, especially multiple episodes of ventricular fibrillation leading eventually to cardiac arrest. 6. If the victim survives a few hours, paralysis of the muscles of deglutition, carpopedal spasm, and painful spasms of the extremities. 7. Occasionally localized or generalized urticaria. 8. The above signs and symptoms are related to a variety of metabolic disorders that may occur in acute fluoride poisoning, including hypocalcemia, hypomagnesemia, metabolic and/or respiratory acidosis and sometimes hyperkalemia. /Fluoride/

INITIAL SYMPTOMS FROM INGESTION INCLUDE ... SALIVATION, NAUSEA, ABDOMINAL PAIN, VOMITING, AND DIARRHEA ARE FREQUENT. ... THE PATIENT SHOWS SIGNS OF INCR IRRITABILITY OF THE NERVOUS SYSTEM ... HYPOCALCEMIA & HYPOGLYCEMIA ARE FREQUENT LAB FINDINGS. ... BLOOD PRESSURE FALLS ... DUE TO CENTRAL VASOMOTOR DEPRESSION AS WELL AS DIRECT TOXIC ACTION ON CARDIAC MUSCLE. THE RESPIRATORY CENTER IS FIRST STIMULATED & LATER DEPRESSED. DEATH ... FROM EITHER RESPIRATORY PARALYSIS OR CARDIAC FAILURE. /FLUORIDE SALTS/

... THE MAJOR MANIFESTATIONS OF CHRONIC INGESTION OF EXCESSIVE AMT OF FLUORIDE ARE OSTEOSCLEROSIS & MOTTLED ENAMEL. ... DENSITY AND CALCIFICATION OF BONE ARE INCREASED ... THOUGHT TO REPRESENT THE REPLACEMENT OF HYDROXYAPATITE BY THE DENSER FLUOROAPATITE. /FLUORIDE SALTS/

CHRONIC POISONING: INTAKE OF MORE THAN 6 MG ... /A/ DAY RESULTS IN FLUOROSIS. SYMPTOMS ARE WT LOSS ... ANEMIA, WEAKNESS, GENERAL ILL HEALTH, STIFFNESS OF JOINTS ... ./FLUORIDE/

TOXIC BY INHALATION.

In experimental animals, the fluosilicates appear to be as toxic as the corresponding fluorides. /Fluosilicates/

/ACUTE POISONING/ IF SUFFICIENT FLUORIDE IS ABSORBED ... FLUORIDE ION INCREASES CAPILLARY PERMEABILITY AND ALSO PRODUCES A COAGULATION DEFECT. THESE ACTIONS LEAD TO HEMORRHAGIC GASTROENTERITIS & HEMORRHAGES, CONGESTION, & EDEMA IN VARIOUS ORGANS INCL THE BRAIN. CLINICAL MANIFESTATIONS ... INCLUDE EXCITABILITY, MUSCLE TREMORS, WEAKNESS, URINATION, DEFECATION, SALIVATION, EMESIS, SUDDEN COLLAPSE, CLONIC CONVULSIONS, COMA, & DEATH DUE TO RESP & CARDIAC FAILURE. CYANOSIS & EARLY RIGOR MORTIS ... . /FLUORIDE/

Typical symptoms of acute toxicity /as seen in chickens/ are reduction or loss of appetite, local or general congestion, and sub-mucosal hemorrhages of the gastrointestinal tract. /Fluoride/

The visible effects of toxic concn of fluoride on plants ... may include chlorosis, peripheral necrosis, leaf distortion, and malformation or abnormal fruit development. /Fluoride/

LD50 ranges of sodium, potassium, or ammonium fluorosilicates administered intragastrically in rats and mice were 89-128 and 45-64 mg fluoride ion/kg, respectively. Severe cornea damage was observed 3 hr after the administration of 50 mg of any of the salts into rabbits' eyes. Min toxic dose (intragastric) of fluorosilicic acid in rats was 8 mg/kg. Min toxic concn in 4 hr inhalation of the salt aerosols were 7.4-9.6 mg/cu m; nontoxic concn was 0.8 mg/cu m. Main toxic effects were decreased activities of cholinesterase and lactate dehydrogenase in blood serum. The intragastric effects of the fluorosilicates were similar to and additive with those of sodium fluoride.

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 m1 of water for dilution if the patent can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Fluorine and related compounds/

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who Is unconscious or in respiratory arrest. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start an IV with D5W TKO /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's to support vital signs if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors for hypotension with a normal fluid volume. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Fluorine and related compounds/

Ammonium silicofluoride is an indirect food additive for use only as a component of adhesives. For use only as a bonding agent for aluminum foil, stabilizer, or preservative. Total fluoride from all sources not to exceed one percent by weight of the finished adhesive.

Persons in charge of vessels or facilities are required to notify the National Response Center (NRC) immediately, when there is a release of this designated hazardous substance, in an amount equal to or greater than its reportable quantity of 1000 lb or 454 kg. The toll free number of the NRC is (800) 424-8802; In the Washington D.C. metropolitan area (202) 426-2675. The rule for determining when notification is required is stated in 40 CFR 302.4 (section IV. D.3.b).

Used as an insecticide, miticide, mothproofing agent, wood preservative, and disinfectant (brewing industry); Also used in soldering flux, laundry sours, glass etching, light metal casting, electroplating, and dental prophylaxis; [HSDB]

Metal Preparation and Pouring [Category: Foundry]

For ammonium silicofluoride (USEPA/OPP Pesticide Code: 075301) there are 0 labels match. /SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./

/FORMER USE:/ INSECTICIDE /DRI-DIE/

WOOD PRESERVATIVE

IN PROPHYLACTIC DENTAL PREPARATION

(1972) 2.5X10+7 G

(1973) 2.8X10+7 G

(1984) 2.09X10+8 g

(1986) 160,000 lb

NEUTRALIZATION OF FLUOROSILICIC ACID WITH EITHER GASEOUS OR AQUEOUS AMMONIA

The manufacture of fluosilicates, especially the sodium salt, is carried out by neutralization of fluosilicic acid. The operation is carried out under vigorous agitation, with control of the ratio of reagents in order not to simultaneously produce the fluoride by introduction of excess alkali. /Fluorosilicates/

CHEMICAL COMPOSITION /OF DRI-DIE IS/ SILICA AEROGEL WITH AMMONIUM FLUOSILICATE TO 3% FLUORINE CONTENT.

/DRIANONE IS A/ FORMULATION OF AMMONIUM FLUOSILICATE, PYRETHRINS, PIPERONYL BUTOXIDE WITH SILICA GEL AND OIL

Grades or purity: Pure, 99+%; commercial, 98+%

Laidlaw U-San-O Moth proofing spray: Soluble concentrate, 13.5% ammonium fluosilicate as active ingredient.

For more Formulations/Preparations (Complete) data for AMMONIUM SILICOFLUORIDE (6 total), please visit the HSDB record page.

Silicate(2-), hexafluoro-, ammonium (1:2): ACTIVE

Ammonium bifluoride solubilizes silica and silicates by forming ammonium fluorosilicate ... .

Vacuum crystallization is necessary to increase the yield, or crystallization must be carried out at low temperature. The precipitates are washed and dried.