diethyl 4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
diethyl 4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate · diethyl 4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate · 4-(2-CHLORO-PH)-2,6-DIMETHYL-1,4-2H-PYRIDINE-3,5-DICARBOXYLIC ACID DIETHYL ESTER · 3,5-diethyl 4-(2-chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate · 4-(2-Chlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid-3,5-diethyl ester · 3,5-Pyridinedicarboxylicacid, 4-(2-chlorophenyl)-1,4-dihydro-2,6-dimethyl-, 3,5-diethyl ester · 5-O-ethyl 7-O-methyl 6-(2-chlorophenyl)-8-methyl-3,4-dihydro-2H-1,4-benzoxazine-5,7-dicarboxylate
Identifikatoren & physikalische Daten
| CAS No. | 34148-67-9 |
|---|---|
| Summenformel | C19H22ClNO4 |
| Durchschnittliche Molmasse | 363,841 g/mol |
| Monoisotopische Masse | 363,12373586 g/mol |
| SMILES | CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1ccccc1Cl |
| InChIKey | HQAADEKEJNBOLM-UHFFFAOYSA-N |
| PubChem CID | 285821 |
| ChEMBL | CHEMBL2063821 |
| EC No. | 104-501-6 |
| DTXSID | DTXSID30301431 |
Chemische & physikalische Eigenschaften
| Schmelzpunkt | 122-123 °C |
|---|---|
| Siedepunkt | 225 °C(Press: 1.5 Torr) |
| Dichte | 1.191±0.06 g/cm3(Predicted) |
| pKa (Säurekonstante) | 2.94±0.70(Predicted) |
Anwendungen & Verwendung
Verwenden
Diethyl 4-(2-Chlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate is an impurity ofAmlodipine (A633495),a dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer.