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HCID 29131Erstellt: 27. Oktober 2026

Chromium(6+)

chromium(6+) · CHROMATE(VI) · CHROMIUM(VI) ION) · HEXAVALENTCHROMATE · chromium(+6) cation · Chromium(6+) compounds · chromium hexavalent ion · HEXAVALENTCHROMIUMCOMPOUNDS

https://huagongshe.com/de/chemical/29131

Molekülstruktur von Chromium(6+)

Identifikatoren & physikalische Daten

CAS No.18540-29-9
SummenformelCr+6
Durchschnittliche Molmasse51,996 g/mol
Monoisotopische Masse51,940505 g/mol
SMILES[Cr+6]
InChIKeyJOPOVCBBYLSVDA-UHFFFAOYSA-N
PubChem CID29131
ChEBICHEBI:33007
EC No.606-053-1
DTXSIDDTXSID7023982

Chemische & physikalische Eigenschaften

Polarare Oberfläche (TPSA)0
H-Brücken-Donoren0
H-Brücken-Akzeptoren0
Frei drehbare Bindungen0
Schwere Atome1
Formalladung6
Komplexität0
CAS Datenbank18540-29-9
EPA chemische InformationenChromium(VI) (18540-29-9)

Sicherheit & Vorschriften

GHS-EinstufungDangerH317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]H350 (41.5%): May cause cancer [Danger Carcinogenicity]H350i (56.9%): May cause cancer by inhalation [Danger Carcinogenicity]H400 (100%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]H410 (100%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]P203, P261, P272, P273, P280, P302+P352, P318, P321, P333+P317, P362+P364, P391, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 65 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
Regulatorische InformationenHazard Traits - CarcinogenicityDermatotoxicityDevelopmental ToxicityHematotoxicityHepatotoxicity and Digestive System ToxicityReproductive ToxicityRespiratory ToxicityAuthoritative List - CA MCLsCA TACsCWA 303(c)EC Annex VI CMRs - Cat. 1BIARC Carcinogens - 1IRIS Carcinogens - Carcin.NTP RoC - knownOEHHA RELsProp 65Report - regardless of intended function of ingredient in the productRegulation (EC) No 178/2002 (amended)
Hazard Classes and CategoriesSkin Sens. 1 (100%)Carc. 1B (41.5%)Carc. 1B (56.9%)Aquatic Acute 1 (100%)Aquatic Chronic 1 (100%)
Minimum Risk LevelIntermediate Oral: 0.005 mg/kg/day (L134) Chronic Oral: 0.001 mg/kg/day (L134)

Anwendungen & Verwendung

Verwenden

The steel industry is the major consumer of chromium. In 2007, estimated consumption of chromium in the United States by end use was 78% in stainless and heat-resisting steel, 13.8% for other steel uses, 3.7% in superalloys, and 4.5% in other alloys and end uses (Papp 2009). Alloys of stainless steel and chromium typically contain between 11.5% and 30% chromium (ATSDR 2000). Chromium(VI) compounds are widely used as corrosion inhibitors, in the manufacture of pigments, in metal finishing and chrome plating, in stainless steel production, in leather tanning, and in wood preservatives (Costa 1997, ATSDR 2000). In 1996, about 52% of all chromium compounds used in the U.S. chemical industry were used in production of wood preservatives; the rest were used in leather tanning (13%), metals finish-ing (13%), pigments (12%), refractories (linings for high-temperature industrial furnaces) (3%), and other uses (7%) (ATSDR 2000). The use of chromium(VI) compounds in wood preservatives increased dramatically from the late 1970s to the early 2000s; however, this use is expected to decrease because of a voluntary phase-out of all residential uses of wood treated with chromated copper arsenate (pressure-treated wood) that went into effect December 31, 2003 (Brooks 2009). Chromium(VI) compounds are also used in textile-dyeing processes, printing inks, drilling muds, pyrotechnics, water treatment, and chemical synthesis (HSDB 2009). Calcium chromate is used primarily as a corrosion inhibitor and as a depolarizer in batteries (IARC 1973, 1990, HSDB 2009). Chromium trioxide is used primarily in chrome plating and other metal finishing (particularly in the production of automobiles and military aircraft), in production of wood preservatives, as a corrosion inhibitor, and in production of organic chemicals and catalysts. Lead chromate has been used in paints and printing inks and as a colorant in vinyl, rubber, and paper. Potassium chromate is used in production of dyes and in textile-dyeing processes. Potassium dichromate has largely been replaced by sodium dichromate in many applications; however, it is still used in photomechanical processes and production of pigments and wood preservatives. Sodium chromate is used as a corrosion inhibitor and in textile dyeing processes, inks, paints, leather tanning, wood preservatives, drilling muds, cutting oils, water treatment, and production of other chromium compounds. Sodium dichromate is the primary base material for the production of chromium compounds and is used as a corrosion inhibitor, in metal treatments, in drilling muds, and in the production of dyes, wood preservatives, synthetic organic chemicals, and catalysts. Strontium chromate is used as a corrosion inhibitor and metal conditioner, in aluminum flake coatings, as a colorant in polyvinyl chloride, in pyrotechnics, in chrome plating, and for sulfate ion control in electrochemical processes. Zinc chromates are used as corrosion inhibi

Intermediate Oral: 0.005 mg/kg/day (Hexavalent chromium) (L134) Chronic Oral: 0.001 mg/kg/day (Hexavalent chromium) (L134)
TreatmentThere is no known antidote for chromium poisoning. Exposure is usually handled with symptomatic treatment. (L16)
Cancer SitesGastrointestinalRespiratory
ZielorganeDevelopmentalGastrointestinalHematologicHepaticRespiratory
Gesundheitliche AuswirkungenHexavalent chromium is a known carcinogen. Chronic inhalation especially has been linked to lung cancer. Hexavalent chromium has also been know to cause reproductive and developmental defects. (A12)Hexavalent chromium is a known carcinogen. Chronic inhalation especially has been linked to lung cancer. Hexavalent chromium has also been shown to affect reproduction and development. (A12)
ExpositionspfadeOral (L16)inhalation (L16)dermal (L16)
ToxizitätsübersichtHexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produced during reoxidation of pentavalent chromium by hydrogen peroxide molecules present in the cell. Trivalent chromium may also form complexes with peptides, proteins, and DNA, resulting in DNA-protein crosslinks, DNA strand breaks, DNA-DNA interstrand crosslinks, chromium-DNA adducts, chromosomal aberrations and alterations in cellular signaling pathways. It has been shown to induce carcinogenesis by overstimulating cellular regulatory pathways and increasing peroxide levels by activating certain mitogen-activated protein kinases. It can also cause transcriptional repression by cross-linking histone deacetylase 1-DNA methyltransferase 1 complexes to CYP1A1 promoter chromatin, inhibiting histone modification. Chromium may increase its own toxicity by modifying metal regulatory transcription factor 1, causing the inhibition of zinc-induced metallothionein transcription. (A12, L16, A34, A35, A36)
Signs and SymptomsBreathing hexavalent chromium can cause irritation to the lining of the nose, nose ulcers, runny nose, and breathing problems, such as asthma, cough, shortness of breath, or wheezing. Ingestion of hexavalent chromium causes irritation and ulcers in the stomach and small intestine, as well as anemia. Skin contact can cause skin ulcers. (L16)
EPA IRIS InformationChromium(VI)GastrointestinalRespiratoryDevelopmentalHematologicHepatic9 x 10 ^-4 mg/kg-day3 x 10 ^-5 mg/m^3
Carcinogen ClassificationChromium (VI) compoundsGroup 1: Carcinogenic to humansVolume Sup 7: Overall Evaluations of Carcinogenicity: An Updating of IARC Monographs Volumes 1 to 42, 1987440 pagesISBN 92-832-1411-0 (out of print)Volume 49: (1990) Chromium, Nickel and WeldingVolume 100C: (2012) Arsenic, Metals, Fibres, and Dusts20091, carcinogenic to humans. (L135)
RAIS Toxicity Values0.084SURROGATE. Based on Total Chromium -- use 1:6 ratio (x7)0.0001IRIS Current0.0003ATSDR Final
USGS Health-Based Screening Levels for Evaluating Water-QualityChromium (VI)01032Trace element200.04−4Also see total chromium CASRN 7440473, which has an MCL
Hazard Quotient Level 0.1 or Cancer Risk Level 1E-069.50e-012.00e+019.2e-051.10e-031.10e-018.0E+01(G)
Arbeitsplatzgrenzwert (OEL)TWA: None mg/m3