Tricyclo-decan-9-yl-xanthogenate (racemate)
Grundinformationen
- CAS
83373-60-8- Standard-SMILES
S=C(S)OC1CC2CC1C1CCCC21- InChIKey
PWLXJBSAUKKGCM-UHFFFAOYSA-N- Summenformel
- C11H16OS2
- Durchschnittliche Molmasse
- 228,4 g/mol
- Monoisotopische Masse
- 228,06425748
Überblick
LSM-5150 is a monoterpenoid.
Namen und Bezeichner
- Bevorzugter Name
- Tricyclo-decan-9-yl-xanthogenate (racemate)
- IUPAC
- 8-tricyclo[5.2.1.02,6]decanyloxymethanedithioic acid
- Englischer Name
- D609
- Summenformel
- C11H17KOS2
- Molmasse
- 268.47
Namen und Synonyme
Tricyclo-decan-9-yl-xanthogenate (racemate)CHEMBL116189483373-60-88-Tricyclo[5.2.1.02,6]decanyloxymethanedithioic acidD609CBiol_001959O-Tricyclo[5.2.1.02,6]dec-9-yl dithiocarbonate Potassium salt[?]yloxymethanedithioic acidLopac0_001242KBioGR_000323KBioSS_000323SCHEMBL1535769
Weitere Namen anzeigen
D609 ,98%D609,D-609D-609 POTASSIUMD609 POTASSIUM SALTD609, 10 mM in DMSOD609 potassium salt,98%Tricyclodecan-9-yl xanthateTricyclodecan-9-yl xanthogenatetricyclodecane-9-yl-xanthogenate
BCBcMAP01_000222CHEBI:94441KBio2_000323KBio2_002891KBio2_005459KBio3_000645KBio3_000646Bio1_000245
Datenbank-Bezeichner
- CAS
83373-60-8- PubChem CID
- 2941
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 4,1
- Polarare Oberfläche (TPSA)
- 42,3 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 3
- Frei drehbare Bindungen
- 2
- Schwere Atome
- 14
- Formalladung
- 0
- Komplexität
- 266
Physikochemische Eigenschaften
- storage temp.
- 0 · 0-6°C
- Löslichkeit
- 2 O: · H2O: 300 mg/mL
- Aggregatzustand
- solid
- Farbe
- off-white
- Biologische Quelle
- synthetic (organic)
- Wasserlöslichkeit
- 100 mM · Soluble to 100 mM in water
- InChI
- 1S/C11H16OS2.K/c13-11(14)12-10-5-6-4-9(10)8-3-1-2-7(6)8;/h6-10H,1-5H2,(H,13,14);/q;+1/p-1/t6-,7,8,9-,10;/m1./s1
- InChIKey
- IGULCCCBGBDZKQ-HJPGVBIPSA-M
- SMILES
- [K]SC(=S)OC1CC2CC1C3CCCC23
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
Sicherheitsdaten
- wgk
- 3
- hs_code
- 29333990
- risk_code
- 22
- safety_code
- 24/25
- Speicherklasse
- 11 - Combustible Solids
Chemie und Industrie
Anwendungen
BeschreibungD609 is a xanthate and a competitive inhibitor of phosphatidylcholine-specific phospholipase C (PC-PLC; Ki = 6.4 μM). It has no effect on bacterial phosphatidylinositol-specific PLC, bovine pancreatic PLA2, or phospholipase D. D609 reduces sphingomyelin synthase activity by 55.5 and 90.5% in membrane preparations when used at concentrations of 100 and 200 mg/ml, respectively. Similar to other xanthates, D609 has antioxidant, antiviral, and anti-tumor activities. In addition, it has anti-inflammatory actions, inhibiting LPS-stimulated expression of nitric oxide synthase (NOS) in phagocytes (IC50 = 20 μg/ml) and IL-1β-induced expression of vascular cell adhesion molecule 1 (VCAM-1) in endothelial cells.
VerwendenD609 has been used as a phosphatidylcholine-specific phospholipase C (PC-PLC) inhibitor in mouse bone marrow derived monocytes. D609 has also been reported to significantly reduce the elevated levels of phosphatidylethanolamine binding protein 1 (PEBP1) in apolipoprotein E-/- mice.
Anbieter49 Anbieter
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
上海优宁维生物科技股份有限公司15921930842 15921930842 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
上海微佳禾生物科技有限公司17502176150; 17502176150 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
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