Acivicin

Water 17.9 - 18.2 (mg/mL)

0.1 M Citrate buffer pH 4.3 17.1 - 25.7 (mg/mL)

0.1 M Borate buffer pH 9.0 8.7 - 13.0 (mg/mL)

0.1 N HCl 31 - 35 (mg/mL)

0.1 N NaOH 34.4 - 36.8 (mg/mL)

95% Ethanol 0.8 (mg/mL)

Bulk: A sample stored at 60 °C for 14 days showed no decomposition as indicated by UV absorption, paper chromatography, or ionic chloride determination. Solution: An aqueous solution (18 mg/mL) which was stored at 28°C for 14 days showed less than 1% decomposition by UV absorption, paper chromatography and ionic chloride measurement.

Chemical substances, produced by microorganisms, inhibiting or preventing the proliferation of neoplasms.

Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.

Drugs that are chemically similar to naturally occurring metabolites, but differ enough to interfere with normal metabolic pathways. (From AMA Drug Evaluations Annual, 1994, p2033)

Antimetabolites that are useful in cancer chemotherapy.

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.