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HCID 2968Erstellt: 27. Oktober 2026
Decamethonium
1,10-Bis(trimethylaminio)decane · N,N,N,N',N',N'-Hexamethyldecane-1,10-diaminium · N,N,N,N',N',N'-Hexamethyl-1,10-decanediaminium
https://huagongshe.com/de/chemical/2968
Identifikatoren & physikalische Daten
| CAS No. | 156-74-1 |
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| Summenformel | C16H38N2+2 |
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| Durchschnittliche Molmasse | 258,49 g/mol |
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| Monoisotopische Masse | 258,30349922 g/mol |
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| SMILES | C[N+](C)(C)CCCCCCCCCC[N+](C)(C)C |
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| InChIKey | MTCUAOILFDZKCO-UHFFFAOYSA-N |
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| PubChem CID | 2968 |
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| ChEMBL | CHEMBL1190 |
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| ChEBI | CHEBI:41934 |
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| DTXSID | DTXSID5048394 |
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Chemische & physikalische Eigenschaften
| XLogP | 3,9 |
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| Polarare Oberfläche (TPSA) | 0 |
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| H-Brücken-Donoren | 0 |
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| H-Brücken-Akzeptoren | 0 |
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| Frei drehbare Bindungen | 11 |
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| Schwere Atome | 18 |
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| Formalladung | 2 |
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| Komplexität | 164 |
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| Löslichkeit | Substantial7.04e-06 g/L |
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| Schmelzpunkt | 268-270 °CMP: 188-189 °C /Bromide/268 - 270 °C |
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| Physical Description | Solid |
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| Stability/Shelf Life | AQUEOUS SOLUTIONS ARE STABLE & MAY BE STERILIZED BY AUTOCLAVING. /DECAMETHONIUM BROMIDE/ |
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| Other Experimental Properties | Crystals from methanol = acetone, dec 268-270 °C. Freely soluble in water, alcoholvery slightly soluble in chloroform. Practically insoluble in ether. Aqueous solutions are stable ... /Bromide/ |
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Sicherheit & Vorschriften
| FDA-Anforderungen | Manufacturers, packers, and distributors of drug and drug products for human use are responsible for complying with the labeling, certification, and usage requirements as prescribed by the Federal Food, Drug, and Cosmetic Act, as amended (secs 201-902, 52 Stat. 1040 et seq., as amended21 U.S.C. 321-392). |
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| Entsorgungsverfahren | SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices. |
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| Wechselwirkungen | ... IN MAN ... DECAMETHONIUM ... PRODUCE & MAINTAIN NEUROMUSCULAR BLOCKADE THAT HAS ALL CHARACTERISTICS OF DEPOLARIZING BLOCKADE ... THIS APPLIES IN PARTICULAR TO ITS INTENSIFICATION BY EDROPHONIUM, NEOSTIGMINE, & OTHER ANTI-CHOLINESTERASE AGENTS THAT ANTAGONIZE COMPETITIVE BLOCK.DEPOLARIZING MUSCLE RELAXANTS DECAMETHONIUM...HAVE BEEN SHOWN TO INTERACT WITH PROPRANOLOL...IN PRESENCE OF DIGITALIS, ESP...IF K LOSS, CARDIAC ARRHYTHMIAS, & EVEN CARDIAC ARREST, MAY OCCUR.DEPOLARIZING MUSCLE RELAXANTS DECAMETHONIUM...HAVE BEEN SHOWN TO INTERACT WITH QUINIDINE IN ANIMALS.For more Interactions (Complete) data for DECAMETHONIUM (8 total), please visit the HSDB record page. |
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| Human Toxicity Excerpts | DECAMETHONIUM...APPARENTLY RELEASE/S/ DETECTABLE AMT OF HISTAMINE ONLY WHEN ADMIN IN VERY HIGH DOSES. ... DECAMETHONIUM.../ALSO/ EXHIBIT/S/ MUSCARINIC ACTIONS, BUT ONLY IN EXTREMELY HIGH DOSES... |
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| Non-Human Toxicity Excerpts | ... Pressure rises have been demonstrated in eyes of cats to be produced by contractions of extraocular muscles which are induced by decamethonium or by stimulation of 3rd nerve. /Decamethonium bromide/ |
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| Antidote and Emergency Treatment | ...LACK OF SYNCHRONY MAKES ANTAGONISM OF DECAMETHONIUM DIFFICULT, SINCE ANTAGONISTS OF ONE PHASE ARE SYNERGISTS OF OTHER. THUS, ARTIFICIAL RESP IS ONLY RELIABLE TREATMENT OF OVERDOSE. |
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| Gefahrstoffdaten | 156-74-1(Hazardous Substances Data) |
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