4-Chlorbenzothiazol-2-ylamin

2-Benzothiazolamine, 4-chloro-

HCID 29872CAS 19952-47-7

Grundinformationen

Standard-SMILES
Nc1nc2c(Cl)cccc2s1
InChIKey
OEQQFQXMCPMEIH-UHFFFAOYSA-N
Summenformel
C7H5ClN2S
Durchschnittliche Molmasse
184,65 g/mol
Monoisotopische Masse
183,98619684

Überblick

2-amino-4-chlorobenzothiazole is a cream colored crystalline solid. (NTP, 1992)

Namen und Bezeichner

Bevorzugter Name
2-Benzothiazolamine, 4-chloro-
IUPAC
4-chloro-1,3-benzothiazol-2-amine
Lokaler Name
4-Chlorbenzothiazol-2-ylamin
Englischer Name
2-Amino-4-chlorobenzothiazole
Summenformel
C7H5ClN2S
Molmasse
184.65

Namen und Synonyme

2-AMINO-4-CHLOROBENZOTHIAZOLE19952-47-74-Chloro-1,3-benzothiazol-2-amine2-Benzothiazolamine, 4-chloro-4-Chlorobenzothiazol-2-ylamineBenzothiazole, 2-amino-4-chloro-4-Chloro-2-benzothiazolamineDTXSID0024470EINECS 243-439-5BRN 0136784DTXCID3044704-27-00-04859 (Beilstein Handbook Reference)
Weitere Namen anzeigen
AKOS BB-8273ASISCHEM A34695TIMTEC-BB SBB000250LABOTEST-BB LT000125874-Chlorobenzothiazol-2-amine2-Amino-4-chlorbenzothiazole4-Chlorbenzothiazol-2-ylamin
RefChem:465554243-439-54-chlorobenzo[d]thiazol-2-amineMFCD000057914-Chloro-2-aminobenzothiazoleCHEMBL1413383F1911-00084-chlorobenzothiazole-2-ylamine

Datenbank-Bezeichner

CAS
19952-47-7
PubChem CID
29872
DTXSID
DTXSID0024470
ChEMBL
CHEMBL1413383
UNII
2PAW227HMB
EC Number
243-439-5
Nikkaji
J24.677H

Eigenschaften

Berechnete Struktureigenschaften

XLogP
2,7
Polarare Oberfläche (TPSA)
67,2 Ų
H-Brücken-Donoren
1
H-Brücken-Akzeptoren
3
Frei drehbare Bindungen
0
Schwere Atome
11

Experimentelle und physikochemische Eigenschaften

Solubility · 2 Einträge

less than 1 mg/mL at 68 °F (NTP, 1992)

>27.7 [ug/mL] (The mean of the results at pH 7.4)

Melting Point397 to 401 °F (NTP, 1992)
Physical Description2-amino-4-chlorobenzothiazole is a cream colored crystalline solid. (NTP, 1992)

Physikochemische Eigenschaften

Schmelzpunkt
203 · 203-205 °C (lit.)
Siedepunkt
344.3 · 344.3±34.0 °C(Predicted)
Dichte
1.475 · 1.4750 (rough estimate)
Brechungsindex
1.61 · 1.6100 (estimate)
storage temp.
Keep in dark place,Sealed in dry,Room Temperature
Aggregatzustand
Crystalline Powder

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 4 Einträge

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 45 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Fire HazardsFlash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)
Health HazardsACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits very toxic fumes of chloride ion, SOx and NOx. (NTP, 1992)
Reactive GroupAmines, Phosphines, and Pyridines
Reactivity Profile · 1 Eintrag

A halide- and amine-substituted aromatic compound and organosulfide. Organosulfides are incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. Many of these compounds may liberate hydrogen sulfide upon decomposition or reaction with an acid. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Air and Water ReactionsInsoluble in water.
Hazard Classes and CategoriesSkin Irrit. 2 (100%)

Sicherheit und Schutzausrüstung

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1 Eintrag

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 Eintrag

SMALL SPILLS AND LEAKAGE: If a spill of this chemical occurs, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with acetone and transfer the dampened material to a suitable container. Use absorbent paper dampened with acetone to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with acetone followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Personal Protective Equipment (PPE) · 1 Eintrag

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

Sicherheitsdaten

wgk
2
tsca
TSCA listed
hs_code
29342080
RTECS-Nr.
DL1225000
risk_code
36/37/38-20/21/22
hazard_code
Xi,Xn

Chemie und Industrie

Verwendung und Herstellung

General Manufacturing Information2-Benzothiazolamine, 4-chloro-: ACTIVE

Anbieter50 Anbieter

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
上海策嵘生物科技有限公司[email protected]
成都彼样生物科技有限公司18108052721 · [email protected]

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