| GHS-Einstufung | DangerH260: In contact with water releases flammable gases which may ignite spontaneously [Danger Substances and mixtures which in contact with water, emit flammable gases]P223, P231+P232, P280, P302+P335+P334, P370+P378, P402+P404, and P501 (click each P-code to see the statement)H260 (100%): In contact with water releases flammable gases which may ignite spontaneously [Danger Substances and mixtures which in contact with water, emit flammable gases] |
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| Regulatorische Informationen | Chemical: Calcium hydride (CaH2)Status: Active Update: 08-01-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/26174Calcium hydride: HSNO Approval: HSR001269 Approved with controlsThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
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| Weitere Sicherheitsinformationen | IMAP assessments - Calcium hydride (CaH2): Environment tier I assessment |
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| DOT-Kennzeichnung | Dangerous When Wet |
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| Brandgefahren | Excerpt from ERG Guide 138 [Substances - Water-Reactive (Emitting Flammable Gases)]:· Produce flammable gases on contact with water. |
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| Gesundheitsgefahren | Excerpt from ERG Guide 138 [Substances - Water-Reactive (Emitting Flammable Gases)]:· Inhalation or contact with vapors, substance or decomposition products may cause severe injury or death. |
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| Gefahrenübersicht | Decomposed by water evolving hydrogen[Merck Index] Reacts violently or is ignited by airReacts exothermically with water producing hydrogen and calcium hydroxideA skin and eye irritant[CAMEO] Releases flammable gases on contact with waterMay cause irritation[Alfa Aesar MSDS] See Sodium hydride. See Calcium hydroxide. |
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| DOT-Nummer und Handbuch | 1404 138 |
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| Reaktive Gruppe | Metal Hydrides, Metal Alkyls, Metal Aryls, and Silanes |
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| RCRA-Anforderungen | D003A solid waste containing calcium hydride may become characterized as a hazardous waste when subjected to testing for reactivity as stipulated in 40 CFR 261.23, and if so characterized, must be managed as a hazardous waste. |
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| Reactivity Alerts | Strong Reducing Agent |
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| Reactivity Profile | When silver fluoride is ground with CALCIUM HYDRIDE the mass becomes incandescent [Mellor 3:389 1946-47]. Heating the hydride strongly with chlorine, bromine, or iodine leads to incandescence. Mixtures of the hydride with various bromates, i.e. barium bromatechlorates, i.e. barium chlorate, and perchlorates, i.e. potassium perchlorateexplode on grinding, [Mellor, 1946, vol. 3, 651]. CaH2 reacts incandescently with AgF if subject to friction. (Mellor, 1941, Vol. 3, 389, 651). |
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| DOT Hazard Classification | Calcium hydrideUN1404Div 4.3 Dangerous when wet material (49 eCFR § 173.124)PG I: the degree of danger presented by the material is great |
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| Brandbekämpfung | Excerpt from ERG Guide 138 [Substances - Water-Reactive (Emitting Flammable Gases)]: |
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| Freisetungsmaßnahmen | · CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. |
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| Erste Hilfe | Excerpt from ERG Guide 138 [Substances - Water-Reactive (Emitting Flammable Gases)]:General First Aid: |
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| Expositionsschutz und Persönliche Schutzausrüstung | · Wear positive pressure self-contained breathing apparatus (SCBA). |
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| Freisetung ohne Brand | Excerpt from ERG Guide 138 [Substances - Water-Reactive (Emitting Flammable Gases)]: |
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| Entsorgungsverfahren | SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air qualitypotential migration in soil or watereffects on animal and plant lifeand conformance with environmental and public health regulations.SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal. |
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| Preventive Measures | SRP: The scientific literature for the use of contact lenses by industrial workers is inconsistent. The benefits or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.SRP: Contaminated protective clothing should be segregated in such a manner so that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. The completeness of the cleaning procedures should be considered before the decontaminated protective clothing is returned for reuse by the workers. Contaminated clothing should not be taken home at the end of shift, but should remain at employee's place of work for cleaning.If the chemical got onto the clothed portion of the body, remove the contaminated clothes as quickly as possible, protecting your own hands and body. Place the victim under a deluge shower. If the chemical got on the victim's exposed skin, such as the hands: Gently and thoroughly wash the contaminated skin with running water and non-abrasive soap. If irritation persists, seek medical attention. Wash contaminated clothing before reusing. |
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| Isolation and Evacuation | Excerpt from ERG Guide 138 [Substances - Water-Reactive (Emitting Flammable Gases)]:Immediate precautionary measure |
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| Protective Action Criteria (PAC) | 12 [mg/m3]130 [mg/m3]790 [mg/m3] |
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| Personal Protective Equipment (PPE) | Excerpt from ERG Guide 138 [Substances - Water-Reactive (Emitting Flammable Gases)]:Splash goggles. Lab coat. Vapor and dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. |
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| Emergency Response Planning Guidelines | · DO NOT USE WATER OR FOAM. |
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| Unerwünschte Wirkungen | Dermatotoxin - Skin burns. |
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| Non-Human Toxicity Excerpts | /LABORATORY ANIMALS: Neurotoxicity/ This study explored the effect of coral calcium hydride (CCH) on rat intrahippocampal antioxidant ability by measuring the /3-methoxycarbonyl-2,2,5,5-tetramethylpyrrolidine-1-oxyl/ (PCAM) nitroxide radical decay ratio when CCH was (a) co-perfused into the hippocampus and (b) fed orally to the rats for 4 weeks under a freely moving state. Estimation of the in vivo antioxidant effect was obtained by administration of the blood-brain barrier-permeable PCAM nitroxide radical and the measured PCAM radical decay ratio then correlated to the amount of antioxidant in the brain using electron spin resonance (ESR) spectroscopy combined with microdialysis. The half-life periods of PCAM in rats treated with CCH in both the co-perfusion and orally fed groups were significantly shorter compared to the control group. These results clarify the mechanism that CCH may exert antioxidant activity by significantly enhancing the basal endogenous antioxidant ability in the hippocampus through a synergistic effect with alpha-tocopherol and ascorbic acid./ALTERNATIVE and IN VITRO TESTS/ Recent studies strongly support the hypothesis that an antioxidant diet inhibits the pathologic aging process as shown in senescence-accelerated mouse prone 8 (SAM/P-8). In our previous study in coral calcium hydride (CCH), we reported that a diet rich in antioxidants inhibited the pathologic aging process, increased the endogenous antioxidant ability, and contributed to prolonging the lifespan of SAM/P-8. To test the hypothesis that antioxidant CCH supplementation to SAM/P-8 mice would change the gene expression and to understand how CCH reverses the acceleration of aging in SAM/P-8 mice, /researchers/ used a DNA array to compare the expression levels in the hippocampus of the brains from 16-week-old SAM/P-8 mice that were either treated or not treated with CCH. The most significant up-regulated changes in the gene network of SAM/P-8 mice were free radical scavenging and molecular transport, whereas genes associated with cell death, cancer, and cell cycle were down-regulated. Findings regarding the changes in these messenger RNA might be associated with the inhibition of the acceleration of aging, as observed in SAM/P-8 mice fed a CCH diet. |
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| Antidote and Emergency Treatment | Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Corrosives/Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Corrosives/Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Early intubation, at the first sign of upper airway obstruction, may be necessary. Positive pressure ventilation techniques with a bag valve mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's (LR) if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload .... . Treat seizures with diazepam or lorazepam ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Corrosives/ |
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