gamma-endorphin, des-Tyr(1)-

HCID 3035192CAS 67810-56-4
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Grundinformationen

Standard-SMILES
CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CN)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)O)[C@@H](C)O)C(C)C)[C@@H](C)O)[C@@H](C)O
InChIKey
YQEWLSJJOSZFHG-DSFKZNPVSA-N
Summenformel
C74H122N18O25S
Durchschnittliche Molmasse
1.695,9 g/mol

Namen und Bezeichner

Bevorzugter Name
gamma-endorphin, des-Tyr(1)-
IUPAC
(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S,3R)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-4-carboxybutanoyl]amino]hexanoyl]amino]-3-hydroxypropanoyl]amino]-5-oxopentanoyl]amino]-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoic acid
Englischer Name
GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-THR-LEU
Summenformel
C74H122N18O25S
Molmasse
1695.93

Namen und Synonyme

Dtgammae67810-56-4(Des-tyr(1))-gamma-endorphinbeta-Lph(62-77)1-De-tyr-gamma-endorphinbeta-Lipotropin(62-77)gamma-Endorphin, des-tyr(1)-gamma-Endorphin, des-tyrosine(1)-RefChem:142297[Des-Tyr1]-gamma-Endorphin[Des-Tyr1] g-Endorphin1-De-L-tyrosine-16a-L-leucine-alpha-endorphin (sheep)
Weitere Namen anzeigen
β-lipotropin 62-77des-tyr1-γ-endorphinBETA-ENDORPHIN (2-17)BETA-LIPOTROPIN (62-77)DES-TYR1-GAMMA-ENDORPHINdes-tyr(1)-gamma-endorphi2-16-α-Endorphin (sheep), 16a-L-leucine-GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-THR-LEU
orb2645914alpha-Endorphin (sheep), 1-de-L-tyrosine-16a-L-leucineYQEWLSJJOSZFHG-DSFKZNPVSA-NHY-P10498TP2751CS-1102343H-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-OH

Datenbank-Bezeichner

CAS
67810-56-4
PubChem CID
3035192
Nikkaji
J573.420G

Eigenschaften

Berechnete Struktureigenschaften

XLogP
-9,6
Polarare Oberfläche (TPSA)
724 Ų
H-Brücken-Donoren
24
H-Brücken-Akzeptoren
28
Frei drehbare Bindungen
55
Schwere Atome
118

Physikochemische Eigenschaften

storage temp.
20 °C · −20°C
Aggregatzustand
Solid

Sicherheit und Regulatorisches

Sicherheitsdaten

wgk
3

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological Classification · 1 Eintrag

Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.

Anbieter26 Anbieter

Hangzhou Go Top Peptide Biotech0571-88211921 · [email protected]
上海鸿肽生物科技有限公司15318089928 · [email protected]
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
杭州思诺达医药科技有限责任公司0571-87213919 17306812703 · [email protected]
太原百利恒康生物技术有限公司19135651983 · [email protected]

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