D-arabino-Hexose, 3,6-dideoxy-
Grundinformationen
- CAS
5658-12-8- Standard-SMILES
C[C@@H](O)[C@H](O)C[C@H](O)C=O- InChIKey
GNTQICZXQYZQNE-NGJCXOISSA-N- Summenformel
- C6H12O4
- Durchschnittliche Molmasse
- 148,16 g/mol
- Monoisotopische Masse
- 148,07355886
Namen und Bezeichner
- Bevorzugter Name
- D-arabino-Hexose, 3,6-dideoxy-
- IUPAC
- (2S,4R,5R)-2,4,5-trihydroxyhexanal
- Englischer Name
- tyvelose
- Summenformel
- C6H12O4
- Molmasse
- 148.16
Namen und Synonyme
D-arabino-Hexose, 3,6-dideoxy-(2S,4R,5R)-2,4,5-trihydroxyhexanaltyveloseD-Tyvelose3,6-Dideoxy-3,6-Dideoxy-D-mannose
Datenbank-Bezeichner
- CAS
5658-12-8- PubChem CID
- 3035457
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- -1,4
- Polarare Oberfläche (TPSA)
- 77,8 Ų
- H-Brücken-Donoren
- 3
- H-Brücken-Akzeptoren
- 4
- Frei drehbare Bindungen
- 4
- Schwere Atome
- 10
- Formalladung
- 0
- Komplexität
- 104
Physikochemische Eigenschaften
- Schmelzpunkt
- NA
- Siedepunkt
- 125 · 125-150 °C(Press: 0.05 Torr)
- Dichte
- 1.249 · 1.249±0.06 g/cm3(Predicted)
- storage temp.
- Refrigerator, Under Inert Atmosphere
- Löslichkeit
- Methanol (Slightly), Water (Slightly)
- Aggregatzustand
- Solid
- pka
- 13.08 · 13.08±0.20(Predicted)
- Farbe
- Off-White to Pale Beige
- Stabilität
- Hygroscopic
Chemie und Industrie
Anwendungen
BeschreibungTyvelose is an unusual 3,6-dideoxyhexose terminal sugar and the immunodominant component of glycoprotein antigens in the parasitic helminth T. spiralis, which is responsible for trichinosis in humans. It is produced in high amounts by the infective larva and is immunodominant during the muscle stage of infection. Mice immunized with tyvelose-BSA produce IgG1 antibodies to tyvelose but are not resistant to infection by T. spiralis. Tyvelose-specific antibodies (2.5 mg/20 g) administered to rat pups leads to expulsion of first stage larvae from the intestine within one hour.
VerwendenThe unusual sugar Tyvelose is the immunodominant portion of the major larval glycoprotein antigens of Trichinella spiralis, which play an important role in generating immunity against the intestinal stages of infection.
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安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
MedBio脉铂医药021-69568360 18916172912 · [email protected]
凯试（上海）科技有限公司021-50135380 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
艾吉析科技（上海）有限公司17717235263 17717235263 · [email protected]
上海宏叶生物科技有限公司400-9205774 400-920-5774 · [email protected]
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TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
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