CGS 21680
Daten werden ergänzt – lade die Seite später neu, um den aktuellen Stand zu sehen
Grundinformationen
- CAS
120225-54-9- Standard-SMILES
CCNC(=O)[C@H]1O[C@@H](n2cnc3c(N)nc(NCCc4ccc(CCC(=O)O)cc4)nc32)[C@H](O)[C@@H]1O- InChIKey
PAOANWZGLPPROA-RQXXJAGISA-N- Summenformel
- C23H29N7O6
- Durchschnittliche Molmasse
- 499,528 g/mol
- Monoisotopische Masse
- 499,21793165
Namen und Bezeichner
- Bevorzugter Name
- CGS 21680
- IUPAC
- 3-{4-[2-({6-Amino-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxyoxolan-2-yl]-9H-purin-2-yl}amino)ethyl]phenyl}propanoic acid
- Englischer Name
- CGS 21680
- Summenformel
- C23H29N7O6
- Molmasse
- 499.52
Namen und Synonyme
C061282Cgs-21680c2-(4-(2-Carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine2-[4-(carboxyethyl)phenylethylamino]-5'-N-ethylcarboxamidoadenosine2-[[2-[4-(2-Carboxyethyl)phenyl]ethyl]amino]-5'-ethylamino-5'-oxo-5'-deoxyadenosine2-[[2-[4-(3-Hydroxy-3-oxopropyl)phenyl]ethyl]amino]-5'-deoxy-5'-oxo-5'-(ethylamino)adenosine3-(4-(2-((6-Amino-9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxytetrahydro-furan-2-yl)-9H-p4-[2-[[6-Amino-9-(N-ethyl-b-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acidBenzenepropanoic acid, 4-[2-[[6-amino-9-(N-ethyl-β-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]-4-[2-[[6-Amino-9-(N-ethyl-beta-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid
Datenbank-Bezeichner
- CAS
120225-54-9- PubChem CID
- 3086599
- DTXSID
DTXSID6043882- ChEMBL
CHEMBL331372- ChEBI
CHEBI:73283- UNII
- T5HB1E831H
Eigenschaften
Physikochemische Eigenschaften
- Dichte
- 1.6 · 1.60
- storage temp.
- 2 · under inert gas (nitrogen or Argon) at 2–8 °C
- Löslichkeit
- 3.4 mg/mL · Soluble up to 3.4 mg/mL in DMSO and 20 mg/mL in 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin.
- Aggregatzustand
- Solid
- pka
- 4.67 · 4.67±0.10(Predicted)
Chemie und Industrie
Anwendungen
VerwendenCGS 21680 hydrochloride is currently used in research in studying neuronal transmission, also in respiration. CGS 21680 is commonly used to study the actions of the adenosine A2A receptor in cells and tissues. CGS 21680 HCl is an adenosine A2 receptor agonist with IC50 of 22 nM, exhibits 140-fold over A1 receptor. CGS 21680C effectively increases coronary flow with an ED25 value of 1.8 nM. In hippocampal slices, CGS 21680 apis weak agonist on pre- and postsynaptic measures of electrophysiologicaJ activity.
Anbieter38 Anbieter
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
咸宁深蓝生物医药研发有限公司18171815831 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
湖北科乐精细化工有限公司027-59101668 19945030958 · [email protected]
Hangzhou Sage Chemical Co., Ltd.+86057186818502 13588463833 · [email protected]
欧利希（湖北）医药科技有限公司17316404525 17316404525 · [email protected]
上海梅凯科技有限公司021-68689288 15300790979 · [email protected]
武汉丰泰威远科技有限公司+86-27-8746-5837 +86-18627785180 · [email protected]
武汉丰泰威远科技有限公司
Zugehörige Reaktionen
1
Notizen zur Verbindung
Wird geladen…