p-Chloroamphetamine
Grundinformationen
- CAS
64-12-0- Standard-SMILES
CC(N)Cc1ccc(Cl)cc1- InChIKey
WWPITPSIWMXDPE-UHFFFAOYSA-N- Summenformel
- C9H12ClN
- Durchschnittliche Molmasse
- 169,65 g/mol
- Monoisotopische Masse
- 169,06582706
Überblick
Parachloroamphetamine is a chlorinated neurotoxic derivative of amphetamine. Although the exact mechanism of action has yet to be fully elucidated, parachloroamphetamine (PCA) neurotoxicity appears to be the result of unrestrained release of both serotonin and dopamine; PCA is used by researchers to selectively kill serotonergic neurons.
Namen und Bezeichner
- Bevorzugter Name
- p-Chloroamphetamine
- IUPAC
- 1-(4-chlorophenyl)propan-2-amine
- Englischer Name
- p-Chloroamphetamine
- Summenformel
- C9H12ClN
- Molmasse
- 169.65
Namen und Synonyme
p-CHLOROAMPHETAMINEp-Chloramphetaminepara-Chloroamphetamine4-Chloroamphetamine1-(4-chlorophenyl)propan-2-amine64-12-0Para Chloroamphetaminealpha-Methyl-p-chlorophenethylamineBenzeneethanamine, 4-chloro-alpha-methyl-DTXSID90897229897NVD4A52NSC-287208
Weitere Namen anzeigen
4-ChloramphetamineDL-p-Chloroamphetamineα-Methyl-p-chlorophenethylaminep-Chloro-α-methylphenethylamine1-(4-Chlorophenyl)-2-propanamineBenzeneethanamine,4-chloro-α-methyl-
Phenethylamine, p-chloro-alpha-methyl-NSC287208Parachloroamphetaminep Chloramphetaminep ChloroamphetamineLy123362Ly 123362LY121860
Datenbank-Bezeichner
- CAS
64-12-0- PubChem CID
- 3127
- DTXSID
DTXSID90897229- ChEMBL
CHEMBL358967- UNII
- 897NVD4A52
- Nikkaji
- J124.932K
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 2,4
- Polarare Oberfläche (TPSA)
- 26 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 1
- Frei drehbare Bindungen
- 2
- Schwere Atome
- 11
- Formalladung
- 0
- Komplexität
- 108
Physikochemische Eigenschaften
- Siedepunkt
- 93 · 93-94 °C(Press: 5 Torr)
- Dichte
- 1.0762 g/cm3 · 1.0762 g/cm3
- pka
- 9.8 · pKa 9.80 (Uncertain)
- CAS Datenbank
- 64 · 64-12-0
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological ClassificationDrugs used for their effects on serotonergic systems. Among these are drugs that affect serotonin receptors, the life cycle of serotonin, and the survival of serotonergic neurons.
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