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Ethenzamid

2-Ethoxybenzamide

HCID 3282
NotizenReaktionen
GrundinformationenÜberblickNamen und BezeichnerEigenschaftenSicherheit und RegulatorischesChemie und IndustrieZugehörige ReaktionenNotizen zur Verbindung
TeilstruktursucheÄhnliche Strukturen suchen

Grundinformationen

CAS
938-73-8
Standard-SMILES
CCOc1ccccc1C(N)=O
InChIKey
SBNKFTQSBPKMBZ-UHFFFAOYSA-N
Summenformel
C9H11NO2
Durchschnittliche Molmasse
165,19 g/mol
Monoisotopische Masse
165,07897859

Überblick

2-ethoxybenzamide appears as white or almost-white crystalline powder. Almost odorless. Tasteless. (NTP, 1992)

Namen und Bezeichner

Bevorzugter Name
2-Ethoxybenzamide
IUPAC
2-ethoxybenzamide
Lokaler Name
Ethenzamid
Englischer Name
2-Ethoxybenzamide
Summenformel
C9H11NO2
Molmasse
165.19

Namen und Synonyme

2-ETHOXYBENZAMIDEethenzamide938-73-8o-EthoxybenzamideBenzamide, 2-ethoxy-EthbenzamideEtenzamideEthenzamidEthosalicylLucamidePirosolvinaEtamide
Weitere Namen anzeigen
h.p.209H.P. 209Lindatox
AnovigamEtosalicilEtosalicylKatagrippeProtopyrinTrancalgylEtocilEusal

Datenbank-Bezeichner

CAS
938-73-8
PubChem CID
3282
DTXSID
DTXSID4020581
ChEMBL
CHEMBL1483877
ChEBI
CHEBI:31564
UNII
L929ZCK4BF
EC Number
213-346-4
Nikkaji
J3.352I

Eigenschaften

Berechnete Struktureigenschaften

XLogP
1,2
Polarare Oberfläche (TPSA)
52,3 Ų
H-Brücken-Donoren
1
H-Brücken-Akzeptoren
2
Frei drehbare Bindungen
3
Schwere Atome
12
Formalladung
0
Komplexität
159

Experimentelle und physikochemische Eigenschaften

LogP1.34
Solubilityless than 1 mg/mL at 61 °F (NTP, 1992)
Melting Point270 to 273 °F (NTP, 1992)
Physical Description2-ethoxybenzamide appears as white or almost-white crystalline powder. Almost odorless. Tasteless. (NTP, 1992)

Physikochemische Eigenschaften

Schmelzpunkt
132 · 132-134 °C (lit.)
Siedepunkt
293.03 °C · 293.03°C (rough estimate)
Dichte
1.1603 · 1.1603 (rough estimate)
Brechungsindex
1.562 · 1.5620 (estimate)
storage temp.
Sealed in dry,Room Temperature
Löslichkeit
Chloroform (Slightly), Dichloromethane (Slightly)
pka
15.62 · 15.62±0.50(Predicted)
Aggregatzustand

Sicherheit und Regulatorisches

Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.

GHS-Klassifizierung

GHS Classification · 3 Einträge

This chemical does not meet GHS hazard criteria for 100% (24 of 24) of all reports.

Not Classified

Aggregated GHS information provided per 24 reports by companies from 1 notifications to the ECHA C&L Inventory.

Gefahrenhinweise

Regulatory InformationBenzamide, 2-ethoxy-: Does not have an individual approval but may be used under an appropriate group standard
Fire HazardsFlash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)
Health HazardsACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes of nitrogen oxides. (NTP, 1992)
Reactive GroupAmides and Imides
Reactivity Profile · 1 Eintrag

2-ETHOXYBENZAMIDE is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Air and Water ReactionsInsoluble in water.
Hazard Classes and CategoriesNot Classified

Chemie und Industrie

Pharmakologische Informationen

ATC Code · 2 Einträge

N - Nervous system

QN - Nervous system

MeSH Pharmacological Classification · 1 Eintrag

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.

Verwendung und Herstellung

General Manufacturing InformationBenzamide, 2-ethoxy-: INACTIVE

Vor- und nachgelagerte Produkte

Vorgelagerte Rohstoffe

Solid sodium hydroxide2-HydroxybenzamidChlorethanBromethanDiethylsulfatBenzamide, 2-(ethenyloxy)- (9CI)2-Ethoxy-1-ethynyl-benzene2-Ethoxybenzaldehyd2'-Ethoxyacetophenone2-Nitrobenzamid

Zugehörige Reaktionen

2
Reaktionsaufzeichnung erstellen
Reaktionsgleichung von HRID 124910
HRID 124910als EduktTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaktionsgleichung von HRID 1957946
HRID 1957946als Eduktuspto-grants-2013_04

Notizen zur Verbindung

Wird geladen…

Auf dieser SeiteGrundinformationenÜberblickNamen und BezeichnerEigenschaftenSicherheit und RegulatorischesChemie und IndustrieZugehörige ReaktionenNotizen zur Verbindung
Granular Crystalline Powder
Farbe
White to almost white
Wasserlöslichkeit
0.1 g/100 · <0.1 g/100 mL at 16 ºC
Merck
14 · 14,3731
InChI
InChI=1S/C9H11NO2/c1-2-12-8-6-4-3-5-7(8)9(10)11/h3-6H,2H2,1H3,(H2,10,11)
InChIKey
SBNKFTQSBPKMBZ-UHFFFAOYSA-N
SMILES
C(N)(=O)C1=CC=CC=C1OCC
CAS Datenbank
938 · 938-73-8(CAS DataBase Reference)
NIST chemische Informationen
Ethenzamide(938-73-8)
EPA chemische Informationen
Ethenzamide (938-73-8)

Sicherheit und Schutzausrüstung

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1 Eintrag

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. If symptoms (such as redness or irritation) develop, immediately transport the victim to a hospital.

Nonfire Spill Response · 1 Eintrag

SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Personal Protective Equipment (PPE) · 1 Eintrag

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

Sicherheitsdaten

wgk
2
tsca
TSCA listed
hs_code
29242995
RTECS-Nr.
CU4381000
Toxizität
LD50 orally in mice: 1160 mg/kg (Starmer)
safety_code
24/25
Speicherklasse
11 - Combustible Solids
p-Ethoxybenzamid
2-Fluorbenzamid
2-Ethoxybenzonitrile
Salicylohydrazid
Phenetol
Salicylaldehydoxim

Nachgelagerte Produkte

2-Ethoxybenzoesure

Anbieter100 Anbieter

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