5002-47-1CCCCCCCCCC(=O)OCCN1CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1VIQCGTZFEYDQMR-UHFFFAOYSA-NFluphenazine decanoate is the prodrug of fluphenazine, an antipsychotic drug used for the symptomatic management of psychosis in patients with schizophrenia. It has a role as a phenothiazine antipsychotic drug, a dopaminergic antagonist and a prodrug. It is an organofluorine compound, a member of phenothiazines, a N-alkylpiperazine and a decanoate ester. It is functionally related to a fluphenazine.
5002-47-1DTXSID7023069CHEMBL1200854CHEBI:5124FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
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Danger
H300 (40%): Fatal if swallowed [Danger Acute toxicity, oral]
P203, P233, P260, P261, P264, P270, P271, P272, P280, P284, P301+P316, P301+P317, P302+P352, P304+P340, P317, P318, P321, P330, P332+P317, P333+P317, P342+P316, P362+P364, P403, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 30 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
FLUPHENAZINE DECANOATE
Phenothiazines [CS]; Phenothiazine [EPC]
Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus.
Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as ANTIEMETICS, in the treatment of Tourette syndrome, and for hiccup. Dopamine receptor blockade is associated with NEUROLEPTIC MALIGNANT SYNDROME.
VerwendenFluphenazine Decanoate is used in psychotropic drug treatments like those relating to schizophrenia. Antipsychotic.
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