HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HCID 33944Erstellt: 23. Oktober 2026
N-(2-Aminoethyl)piperidin
1-(2-AMINOETHYL)PIPERIDINE · 2-(PIPERIDIN-1-YL)ETHANAMINE · RARECHEM AL BW 0414 · LABOTEST-BB LT02100617 · 2-PIPERIDINOETHYLAMINE · 2-Piperidinoethanamine · AMINO ETHYL PIPERIDINE · N-AMINOETHYL PIPERIDINE
https://huagongshe.com/de/chemical/33944
Identifikatoren & physikalische Daten
| CAS No. | 27578-60-5 |
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| Summenformel | C7H16N2 |
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| Durchschnittliche Molmasse | 128,22 g/mol |
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| Monoisotopische Masse | 128,13134851 g/mol |
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| SMILES | NCCN1CCCCC1 |
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| InChIKey | CJNRGSHEMCMUOE-UHFFFAOYSA-N |
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| PubChem CID | 33944 |
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| EC No. | 248-540-8 |
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| DTXSID | DTXSID30181977 |
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| Lokaler Name | N-(2-Aminoethyl)piperidin |
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Chemische & physikalische Eigenschaften
| XLogP | 0,4 |
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| Polarare Oberfläche (TPSA) | 29,3 |
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| H-Brücken-Donoren | 1 |
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| H-Brücken-Akzeptoren | 2 |
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| Frei drehbare Bindungen | 2 |
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| Schwere Atome | 9 |
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| Formalladung | 0 |
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| Komplexität | 67,3 |
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| Schmelzpunkt | 67-70 °C(Solv: ligroine (8032-32-4)dichloromethane (75-09-2)) |
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| Siedepunkt | 186 °C(lit.) |
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| Dichte | 0.899 g/mL at 25 °C(lit.) |
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| Brechungsindex | n20/D 1.473(lit.) |
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| Flammpunkt | 136 °F |
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| Lagerbedingungen | under inert gas (nitrogen or Argon) at 2–8 °C |
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| Aggregatzustand | Liquid |
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| pKa (Säurekonstante) | pK1: 6.38pK2: 9.89 (30°C) |
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| Farbe | Clear colorless to yellow |
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| Löslichkeit | Partly miscible in water. |
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| BRN | 103469 |
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| InChI | InChI=1S/C7H16N2/c8-4-7-9-5-2-1-3-6-9/h1-8H2 |
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| InChIKey | CJNRGSHEMCMUOE-UHFFFAOYSA-N |
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| SMILES | N1(CCN)CCCCC1 |
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| CAS Datenbank | 27578-60-5(CAS DataBase Reference) |
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| NIST chemische Informationen | 1-Piperidineethanamine(27578-60-5) |
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Sicherheit & Vorschriften
| GHS-Einstufung | DangerH226 (100%): Flammable liquid and vapor [Warning Flammable liquids]P210, P233, P240, P241, P242, P243, P260, P264, P280, P301+P330+P331, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P321, P363, P370+P378, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 45 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
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| Hazard Classes and Categories | Flam. Liq. 3 (100%) |
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| Wassergefährdungsklasse (WGK) | 3 |
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| UN-Transportnummer | UN 2734 8/PG 2 |
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| Zollcode | 29333990 |
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| R-Sätze (R) | 34 |
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| Gefahrensymbole | C,Xi |
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| hazard_note | Irritant |
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| Sicherheitshinweise (S) | 26-36/37/39-45 |
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| Gefahrenklasse | 3Flam. Liq. 3Skin Corr. 1B |
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| Verpackungsgruppe | III |
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| Lagerklasse | 3 - Flammable liquids |
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Anwendungen & Verwendung
Verwenden
1-(2-Aminoethyl)piperidine is used in modification of vinylbenzyl chloride/divinylbenzene gel copolymer bead and in the synthesis of linkage isomers trans-bis[1-(2-aminoethyl)piperidine]dinitronickel and trans-bis[1-(2-aminoethyl)-piperidine]dinitritonickel. It is also used as a reactant for synthesis of: analogs of anticancer agents, inhibitor of botulinum neurotoxin serotype A light chain, P. falciparum malaria, and Ebola filovirus, cannabinoid CB1 receptor antagonists, small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells, potent and selective 5-HT6 antagonists and N-mustards as anticancer agents. 1-(2-Aminoethyl)piperidine on [1+1] condensation reaction with 3-methoxy salicylaldehyde yields tridentate Schiff base ligand.
