HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
NSC 405020
CS-1114 · NSC 405020 · NSC 405020, >=98% · NSC 405020 ，S8072 · NSC-405020 · NSC 405020, 7497-07-6 · MT1-MMP Inhibitor, NSC405020 · NSC405020, 98%, MT1-MMP inhibitor
Identifikatoren & physikalische Daten
| CAS No. | 7497-07-6 |
|---|---|
| Summenformel | C12H15Cl2NO |
| Durchschnittliche Molmasse | 260,164 g/mol |
| Monoisotopische Masse | 259,05306946 g/mol |
| SMILES | CCCC(C)NC(=O)c1ccc(Cl)c(Cl)c1 |
| InChIKey | ARDYECYBETXQFD-UHFFFAOYSA-N |
| PubChem CID | 346721 |
| ChEMBL | CHEMBL4303335 |
| EC No. | 804-136-9 |
| DTXSID | DTXSID80323865 |
Chemische & physikalische Eigenschaften
| Siedepunkt | 353.7±32.0 °C(Predicted) |
|---|---|
| Dichte | 1.182±0.06 g/cm3(Predicted) |
| Lagerbedingungen | Sealed in dry,Room Temperature |
| Löslichkeit | Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml). |
| Aggregatzustand | powder |
| pKa (Säurekonstante) | 13.38±0.46(Predicted) |
| Farbe | white to beige |
| Stabilität | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months. |
| InChI | 1S/C12H15Cl2NO/c1-3-4-8(2)15-12(16)9-5-6-10(13)11(14)7-9/h5-8H,3-4H2,1-2H3,(H,15,16) |
| InChIKey | ARDYECYBETXQFD-UHFFFAOYSA-N |
| SMILES | Clc1c(ccc(c1)C(=O)NC(CCC)C)Cl |
Sicherheit & Vorschriften
| Wassergefährdungsklasse (WGK) | 3 |
|---|---|
| UN-Transportnummer | 3077 |
| Zollcode | 29242990 |
| R-Sätze (R) | 36 |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 26-24/25 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
NSC 405020 is a novel, selective, and noncatalytic membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor that directly interacts with the homopexin (PEX) domain of MT1-MMP.