Lithiumacetat
quilone · Lithiumacetat · ithium acetate · LITHIUM ACETATE · lithiumethanate · Lithiumethanoat · lithiumethanoate · LithiumAcetate>Acetic acid lithium
Identifikatoren & physikalische Daten
| CAS No. | 546-89-4 |
|---|---|
| Summenformel | C2H3LiO2 |
| Durchschnittliche Molmasse | 66 g/mol |
| Monoisotopische Masse | 66,02930889 g/mol |
| SMILES | CC(=O)[O-].[Li+] |
| InChIKey | XIXADJRWDQXREU-UHFFFAOYSA-M |
| PubChem CID | 3474584 |
| ChEBI | CHEBI:63045 |
| EC No. | 208-914-3 |
| DTXSID | DTXSID00883436 |
| Lokaler Name | Lithiumacetat |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 40,1 |
|---|---|
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 5 |
| Formalladung | 0 |
| Komplexität | 34,6 |
| Stoffklassen | Metals -> Organic Acids, Metal Salts |
| Dichte | 1.28 @ 20°C1.3[at 20℃] |
| Schmelzpunkt | 280 °C283-285 °C (lit.) |
| Physical Description | Other SolidBecomes dihydrate at 56.5 deg C[Merck Index] White powderSoluble in water[MSDSonline] |
| Dampfdruck | 0Pa at 25℃ |
| Lagerbedingungen | Inert atmosphere,Room Temperature |
| Löslichkeit | H2O: 5 M at 20 °C, clear, colorless40.8 g/100 mL (20 ºC) |
| Aggregatzustand | Powder or Crystals |
| Farbe | White to yellow |
| Merck | 14,5521 |
| Stabilität | Stable. Incompatible with strong oxidizing agents. |
| Hauptanwendungen | battery precursorscatalystsmaterial synthesis precursor |
| InChI | InChI=1S/C2H4O2.Li/c1-2(3)4/h1H3,(H,3,4)/q+1/p-1 |
| InChIKey | XIXADJRWDQXREU-UHFFFAOYSA-M |
| SMILES | C([O-])(=O)C.[Li+] |
| LogP (Verteilungskoeffizient) | 0.09 at 25℃ |
| CAS Datenbank | 546-89-4(CAS DataBase Reference) |
| EPA chemische Informationen | Lithium acetate (546-89-4) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 29.7% (102 of 343) of reports.WarningH302 (64.7%): Harmful if swallowed [Warning Acute toxicity, oral]P264, P264+P265, P270, P280, P301+P317, P305+P351+P338, P330, P337+P317, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 343 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | Chemical: Acetic acid, lithium saltAcetic acid, lithium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Acetic acid, lithium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 13-03-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/21532Acetic acid, lithium salt: Does not have an individual approval but may be used under an appropriate group standard |
| Weitere Sicherheitsinformationen | IMAP assessments - Acetic acid, lithium salt: Human health tier I assessment |
| Gefahrenübersicht | May cause irritationAffects the central nervous system when used as a drug[MSDSonline] See Lithium. |
| Hazard Classes and Categories | Acute Tox. 4 (64.7%) |
| Expositionsschutz und Persönliche Schutzausrüstung | 0.2 [mg/m3], inhalable fraction, as Li[German Research Foundation (DFG)] |
| Protective Action Criteria (PAC) | 3.2 [mg/m3]36 [mg/m3]210 [mg/m3] |
| Unerwünschte Wirkungen | Neurotoxin - Other CNS neurotoxin |
| Wassergefährdungsklasse (WGK) | 1 |
| TSCA-Inventar-Status | TSCA listed |
| Zollcode | 29152990 |
| RTECS-Nr. | AI5450000 |
| R-Sätze (R) | 36 |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 23-24/25-39-26-22 |
| Lagerklasse | 11 - Combustible Solids |
| Gefahrenklasse | Acute Tox. 4 OralEye Irrit. 2 |
Anwendungen & Verwendung
Beschreibung
Lithium acetate (CH3COOLi) is a salt of lithium and acetic acid.
Verwenden
Lithium acetate is used in the laboratory as buffer for gel electrophoresis of DNA and RNA. It has a lower electrical conductivity and can be run at higher speeds than can gels made from TAE buffer (5-30V/cm as compared to 5 - 10 V / cm). Lithium boric acid or sodium boric acid are usually preferable to lithium acetate or TAE when analyzing smaller fragments of DNA (less than 500 bp) due to the higher resolution of borate-based buffers in this size range as compared to acetate buffers. Lithium acetate is also used to permeabilize the cell wall of yeast for use in DNA transformation. It is believed that the beneficial effect of LiAc is caused by its chaotropic effect denaturing both DNA, RNA and proteins.