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Ethidium

HCID 3624
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Grundinformationen

CAS
3546-21-2
Standard-SMILES
CC[n+]1c(-c2ccccc2)c2cc(N)ccc2c2ccc(N)cc21
InChIKey
QTANTQQOYSUMLC-UHFFFAOYSA-O
Summenformel
C21H20N3+
Durchschnittliche Molmasse
314,4 g/mol
Monoisotopische Masse
314,16572265

Überblick

Ethidium is the fluorescent compound widely used in experimental cell biology and biochemistry to reveal double-stranded DNA and RNA. It has a role as an intercalator and a fluorochrome. It derives from a hydride of a phenanthridine.

Namen und Bezeichner

Bevorzugter Name
Ethidium
IUPAC
5-ethyl-6-phenylphenanthridin-5-ium-3,8-diamine
Englischer Name
Ethidium
Summenformel
C21H20N3+
Molmasse
314.41

Namen und Synonyme

EthidiumhomidiumEthidium cation3546-21-2BabidiumHomidium cationHomidium ion3,8-Diamino-5-ethyl-6-phenylphenanthridiniumEN464416SIPhenanthridinium, 3,8-diamino-5-ethyl-6-phenyl-RD-1572DTXSID9048487
Weitere Namen anzeigen
Homidium Free BasePHENANTHRIDINIUM,3,8-DIAMINO-5-ETHYL-6-PHENYL-ethidium, Dromilac, 3,8-diamino-5-ethyl-6-phenylphenanthridin-5-ium cation, ethidium bromide, ethidium cation, ethidium ion, ethidium
CHEBI:424782,7-diamino-9-phenyl-10-ethylphenanthridinium3,8-diamino-5-ethyl-6-phenylphenanthridin-5-ium2,7-DIAMINO-10-ETHYL-9-PHENYLPHENANTHRIDINIUMRefChem:921221DTXCID9028461Novidium5-ethyl-6-phenylphenanthridin-5-ium-3,8-diamine

Datenbank-Bezeichner

CAS
3546-21-2
PubChem CID
3624
DTXSID
DTXSID9048487
ChEMBL
CHEMBL48166
ChEBI
CHEBI:42478
UNII

Eigenschaften

Berechnete Struktureigenschaften

XLogP
4,2
Polarare Oberfläche (TPSA)
55,9 Ų
H-Brücken-Donoren
2
H-Brücken-Akzeptoren
2
Frei drehbare Bindungen
2
Schwere Atome
24
Formalladung
1
Komplexität
419

Experimentelle und physikochemische Eigenschaften

Collision Cross Section172.71 Ų [M]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Chemie und Industrie

Pharmakologische Informationen

ATC CodeQP - Antiparasitic products, insecticides and repellents
MeSH Pharmacological Classification · 5 Einträge

Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.

Chemicals that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags.

Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)

Agents destructive to the protozoal organisms belonging to the suborder TRYPANOSOMATINA.

Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists. Nicotinic antagonists block synaptic transmission at autonomic ganglia, the skeletal neuromuscular junction, and at central nervous system nicotinic synapses.

Anbieter5 Anbieter

Syntechem Co.,Ltd[email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
河南威梯希化工科技有限公司0371-63284658 18135795563 · [email protected]
乐山阿普莱化学科技有限公司18011665355 · [email protected]

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Notizen zur Verbindung

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Auf dieser SeiteGrundinformationenÜberblickNamen und BezeichnerEigenschaftenChemie und IndustrieZugehörige ReaktionenNotizen zur Verbindung
EN464416SI
Nikkaji
J5.164K
TargetMol中国(陶术生物)15002134094 · [email protected]

Ergänzende Hinweise

DefinitionChEBI: The fluorescent compound widely used in experimental cell biology and biochemistry to reveal double-stranded DNA and RNA.