2,4'-Dichlorobiphenyl
Grundinformationen
- CAS
34883-43-7- Standard-SMILES
Clc1ccc(-c2ccccc2Cl)cc1- InChIKey
UFNIBRDIUNVOMX-UHFFFAOYSA-N- Summenformel
- C12H8Cl2
- Durchschnittliche Molmasse
- 223,09 g/mol
- Monoisotopische Masse
- 222,0003056
Überblick
2,4'-dichlorobiphenyl is a dichlorobiphenyl that is chlorobenzene in which the hydrogen at position 2 has been replaced by a 4-chlorophenyl group. It is a dichlorobiphenyl and a member of monochlorobenzenes.
Namen und Bezeichner
- Bevorzugter Name
- 2,4'-Dichlorobiphenyl
- IUPAC
- 1-chloro-2-(4-chlorophenyl)benzene
- Englischer Name
- 2,4'-Dichlorobiphenyl
- Summenformel
- C12H8Cl2
- Molmasse
- 223.1
Namen und Synonyme
2,4'-DICHLOROBIPHENYL34883-43-72,4'-Dichloro-1,1'-biphenylPCB 81,1'-Biphenyl, 2,4'-dichloro-DTXSID0022511TTP086070WCHEBI:342321-chloro-4-(2-chlorophenyl)benzeneRefChem:53554681-934-1DTXCID902511
Weitere Namen anzeigen
BZNO 82,4'-CBPCB NO 8C20000800 PCB No. 8Hexanal Impurity 242,4’-dichloro-bipheny2,4’-dichloro-1’-biphenyl
1-chloro-2-(4-chlorophenyl)benzenePCB No. 8Biphenyl, 2,4'-dichloro-CHEMBL1958902,4'-DICHLOROBIPHENYL (IUPAC N.8) (purity)2,4/'-DichlorobiphenylBRN 1946417UNII-TTP086070W
Datenbank-Bezeichner
- CAS
34883-43-7- PubChem CID
- 36982
- DTXSID
DTXSID0022511- ChEMBL
CHEMBL195890- ChEBI
CHEBI:34232- UNII
- TTP086070W
- EC Number
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 5,1
- Polarare Oberfläche (TPSA)
- 0 Ų
- H-Brücken-Donoren
- 0
- H-Brücken-Akzeptoren
- 0
- Frei drehbare Bindungen
- 1
- Schwere Atome
- 14
- Formalladung
- 0
- Komplexität
- 173
Experimentelle und physikochemische Eigenschaften
SpringerMaterials Properties13C nuclear magnetic resonance spectrum
LogP5.09
Endocrine DisruptorsPotential endocrine disrupting compound
Collision Cross Section141 Ų [M]+ [CCS Type: TIMS, Method: calibration with PAHs]
Physikochemische Eigenschaften
- Schmelzpunkt
- 46 °C · 46°C
- Siedepunkt
- 289.78 °C · 289.78°C (rough estimate)
- Dichte
- 1.249 · 1.2490 (rough estimate)
- Brechungsindex
- 1.594 · 1.5940 (rough estimate)
- storage temp.
- Sealed in dry,Room Temperature
- Wasserlöslichkeit
- 0.62 mg/L · 0.62mg/L(25 ºC)
- BRN
- 1946417 · 1946417
- Henry's Law Constant
- 3.8 · 3.8×10-2 mol/(m3Pa) at 25℃, Li et al. (2003)
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Warning
H373 (100%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]
P260, P273, P319, P391, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Warning
H350 (100%): May cause cancer [Danger Carcinogenicity]
Gefahrenhinweise
Regulatory InformationSubstance: 2,4-PCB
Hazard Classes and Categories
Carc. 1B (100%)
STOT RE 2 (100%)
Sicherheit und Schutzausrüstung
Minimum Risk LevelIntermediate Oral: 0.03 ug/kg/day (L134)
Toxikologische Informationen
Treatment
There are no specific treatments for PCB poisoning, since it is not usually recognized until after substantial chronic exposure. Only preventing further exposure and treating the observed symptoms can be done. Acute inhalation can be treated by administering oxygen. (L4)
Health Effects
The most common health effects of PCBs are skin conditions such as chloracne and rashes. Chronic PCB exposure has also been shown to cause liver, stomach and kidney, damage, jaundice, edema, anemia, changes in the immune system, behavioral alterations, and impaired reproduction. (L4)
Chemie und Industrie
Pharmakologische Informationen
Metabolism/Metabolites
PCBs are absorbed via inhalation, oral, and dermal routes of exposure. They are trasported in the blood, often bound to albumin. Due to their lipophilic nature they tend to accumulate in lipid-rich tissues, such as the liver, adipose, and skin. Metabolism of PCBs is very slow and varies based on the degree and position of chlorination. PCBs are metabolized by the microsomal monooxygenase system catalyzed by cytochrome P-450 enzymes to polar metabolites that can undergo conjugation with glutathione and glucuronic acid. The major metabolites are hydroxylated products which are excreted in the bile and faeces. The slow metabolism of PCBs means they tend to accumulate in body tissues. (L4, T6)
Verwendung und Herstellung
Uses
PCBs were used as coolants and lubricants in transformers, capacitors, and other electrical devices (such as fluorescent lights and refridgerators) produced before 1977. PCBs may contaminate the air and water near hazardous waste sites. In addition, PCBs bioaccumulate in the environment and may be found in fish, meat, and dairy products. (L4)
Anwendungen
Verwenden2,4''-Dichlorobiphenyl is a polychlorinated biphenyl (PCB) congeners.
Vor- und nachgelagerte Produkte
Vorgelagerte Rohstoffe
Anbieter42 Anbieter
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