HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Pcb 170
BZ-170 · CB-170 · PCB-170 · BZ NO 170 · PCB NO 170 · PCB170/190 · 2233445HPCB · 2,2′,3,3′,4,4′,5-PCB
Identifikatoren & physikalische Daten
| CAS No. | 35065-30-6 |
|---|---|
| Summenformel | C12H3Cl7 |
| Durchschnittliche Molmasse | 395,3 g/mol |
| Monoisotopische Masse | 391,805444 g/mol |
| SMILES | Clc1ccc(-c2cc(Cl)c(Cl)c(Cl)c2Cl)c(Cl)c1Cl |
| InChIKey | RMPWIIKNWPVWNG-UHFFFAOYSA-N |
| PubChem CID | 37037 |
| EC No. | 634-856-7 |
| DTXSID | DTXSID2073481 |
Chemische & physikalische Eigenschaften
| XLogP | 7,9 |
|---|---|
| Polarare Oberfläche (TPSA) | 0 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 0 |
| Frei drehbare Bindungen | 1 |
| Schwere Atome | 19 |
| Formalladung | 0 |
| Komplexität | 312 |
| Polymers | Polychlorinated biphenyl |
| LogP (Verteilungskoeffizient) | 7.08 |
| Endocrine Disruptors | Potential endocrine disrupting compound |
| Collision Cross Section | 171.4 Ų [M]+ [CCS Type: TIMS, Method: calibration with PAHs] |
| Schmelzpunkt | 135°C |
| Siedepunkt | 479.43°C (rough estimate) |
| Dichte | 1.6580 (rough estimate) |
| Brechungsindex | 1.6330 (rough estimate) |
| Lagerbedingungen | room temp |
| Löslichkeit | Chloroform (Slightly), Methanol (Slightly, Sonicated)3.47ug/L(20 ºC) |
| Farbe | White to Off-White |
| Henry-Konstante | 4.8×10-2 mol/(m3Pa) at 25℃, Bamford et al. (2000) |
| Stabilität | Stable at recommended storage conditions., Stable At Recommended Storage Conditi |
| EPA chemische Informationen | 2,2',3,3',4,4',5-Heptachlorobiphenyl (35065-30-6) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 2.4% (1 of 42) of reports.WarningH373 (97.6%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]P260, P273, P319, P391, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 42 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | Hazard Traits - CarcinogenicityDermatotoxicityDevelopmental ToxicityEndocrine ToxicityHepatotoxicity and Digestive System ToxicityImmunotoxicityReproductive ToxicitySubstance: 2,2',3,3',4,4',5-heptachlorobiphenyl |
| Hazard Classes and Categories | STOT RE 2 (97.6%) |
| Minimum Risk Level | Intermediate Oral: 0.03 ug/kg/day (L134) |
| Treatment | There are no specific treatments for PCB poisoning, since it is not usually recognized until after substantial chronic exposure. Only preventing further exposure and treating the observed symptoms can be done. Acute inhalation can be treated by administering oxygen. (L4) |
| Gesundheitliche Auswirkungen | The most common health effects of PCBs are skin conditions such as chloracne and rashes. Chronic PCB exposure has also been shown to cause liver, stomach and kidney, damage, jaundice, edema, anemia, changes in the immune system, behavioral alterations, and impaired reproduction. (L4) |
| Expositionspfade | Oral (L4)inhalation (L4)dermal (L4) |
| Toxizitätsübersicht | The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66) |
Anwendungen & Verwendung
Verwenden
2,2'',3,3'',4,4'',5-Heptachloro-1,1''-biphenyl is a toxic organic pollutant.