N-(2-hydroxypropyl)methacrylamide

HCID 38622

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Grundinformationen

CAS: 21442-01-3
Standard-SMILES: C=C(C)C(=O)NCC(C)O
InChIKey: OKPYIWASQZGASP-UHFFFAOYSA-N
Summenformel: C7H13NO2
Durchschnittliche Molmasse: 143,18 g/mol
Monoisotopische Masse: 143,09462866

Überblick

Namen und Bezeichner

Bevorzugter Name: N-(2-hydroxypropyl)methacrylamide
IUPAC: N-(2-hydroxypropyl)-2-methylprop-2-enamide
Englischer Name: N-(2-Hydroxypropyl)methacrylamide
Summenformel: C7H13NO2
Molmasse: 143.18

Namen und Synonyme

N-(2-Hydroxypropyl)methacrylamide21442-01-3HPMA polymerR3F262Z4E0poly(hydroxypropyl methacrylamide)RefChem:7879801-057-12-hydroxypropyl methacrylamideN-(2-hydroxypropyl)-2-methylprop-2-enamide2-Propenamide,N-(2-hydroxypropyl)-2-methyl-MFCD00080531N-(2-HYDROXYPROPYL) METHACRYLAMIDE

Weitere Namen anzeigen

DK667DK668DKFELEX0166N-(2-HYDROXYPROPYL)METHACRYLAMIDN-(2-Hydroxypropyl)methacrylamide,98%N - (2-hydroxypropyl) methylacrylamide2-Hydroxypropyl methacrylamide 99% (GC)N-(2-Hydroxypropyl)-2-methyl-prop-2-enamide

2-Propenamide, N-(2-hydroxypropyl)-2-methyl-ACRYLAMIDE, N-(2-HYDROXYPROPYL)-2-METHYL-AKOS006344692HY-W077028SS-48551-(METHACRYLOYLAMINO)PROPAN-2-OLSY2380962-Propenamide, N-(2-hydroxypropyl)-2-me

Datenbank-Bezeichner

CAS: 21442-01-3、40704-75-4
PubChem CID: 38622
DTXSID: DTXSID30944024
UNII: R3F262Z4E0
EC Number: 801-057-1
Nikkaji: J413.991G

Eigenschaften

Berechnete Struktureigenschaften

XLogP: 0,3
Polarare Oberfläche (TPSA): 49,3 Å²
H-Brücken-Donoren: 2
H-Brücken-Akzeptoren: 2
Frei drehbare Bindungen: 3
Schwere Atome: 10
Formalladung: 0
Komplexität: 143

Physikochemische Eigenschaften

Schmelzpunkt: 67.92 °C · 67.92°C
Siedepunkt: 321.2 · 321.2±34.0 °C(Predicted)
Dichte: 1.002 g/mL · 1.002 g/mL ((predicted))
storage temp.: 2 · 2-8°C
Löslichkeit: Soluble in DMSO
pka: 14.43 · 14.43±0.20(Predicted)
Aggregatzustand: powder
Farbe: White to off-white
InChI: 1S/C7H13NO2/c1-5(2)7(10)8-4-6(3)9/h6,9H,1,4H2,2-3H3,(H,8,10)
InChIKey: OKPYIWASQZGASP-UHFFFAOYSA-N
SMILES: CC(O)CNC(=O)C(C)=C

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 4 Einträge

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Sicherheitsdaten

wgk: 3
hs_code: 2924297099
risk_code: 36/37/38
safety_code: 26-36/37/39
Speicherklasse: 11 - Combustible Solids

Chemie und Industrie

Anwendungen · 2 Einträge

BeschreibungN-(2-hydroxypropyl)methacrylamide (HPMA) is an important hydrophilic monomer. Due to the non-toxic, non-immunogenic properties and prolonged circulation time of both its homopolymers and copolymers, it is widely employed in the preparation of PHPMA copolymers (a polymer-drug conjugate) for use in the biopharmaceutical industry. For instance, poly(HPMA-co-MA-GFLG-doxorubicin) represents the first intravenous tumour-targeting polymeric prodrug to enter clinical trials. HPMA polymers and copolymers are also employed in the fabrication of biocompatible medical materials such as hydrogels[1].

VerwendenMonomers to synthesize biocompetible polymers and copolymers for drug carriers, protein conjugates and hydrogels in biomedical applications.

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上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]

武汉欣扬瑞和化学科技有限公司153-07155313 15307155313 · [email protected]

Junwee Chemical co., Ltd.+86-571-85808636 +86-13958122542 · [email protected]

Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]

上海埃玛诺生物科技有限公司17302153218

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