Profenofos

PROFENOPHOS · PROFENFOS · CURACRON · PROFENPHOS · O-(4-BROMO-2-CHLOROPHENYL)-O-ETHYL-S-PROPYL PHOSPHOROTHIOATE · TaMbo · PRAHAR · Calofos

https://huagongshe.com/de/chemical/38779

Identifikatoren & physikalische Daten

CAS No.	41198-08-7
Summenformel	C11H15BrClO3PS
Durchschnittliche Molmasse	373,63 g/mol
Monoisotopische Masse	371,93514 g/mol
SMILES	CCCSP(=O)(OCC)Oc1ccc(Br)cc1Cl
InChIKey	QYMMJNLHFKGANY-UHFFFAOYSA-N
PubChem CID	38779
ChEMBL	CHEMBL2138242
ChEBI	CHEBI:38845
EC No.	255-255-2
DTXSID	DTXSID3032464
Lokaler Name	Profenofos

Chemische & physikalische Eigenschaften

XLogP	4,7
Polarare Oberfläche (TPSA)	60,8
H-Brücken-Donoren	0
H-Brücken-Akzeptoren	4
Frei drehbare Bindungen	7
Schwere Atome	18
Formalladung	0
Komplexität	295
LogP (Verteilungskoeffizient)	log Kow = 4.68
Geruch	Garlic-like
Dichte	1.455 @ 20 °Cd20 1.455
Color/Form	Pale yellow liquidAmber color, oily liquid
Löslichkeit	Readily miscible with most organic solvents.In water, 28 mg/l @ 25 °CDMSO: 50 mg/mL (133.82 mM)28 mg l-1 (25 °C)
Siedepunkt	100 °C @ 1.35X10-2 mm Hg110°C (0.001 torr)
Decomposition	When heated to decomposition it emits very toxic /sulfur oxides, phosphorus oxides, hydrogen bromide, & hydrogen chloride/.... On hydrolysis DT50 (calculated) (20 °C) 93 day (pH 5), 14.6 days (pH 7), 5.7 hr (pH 9).
Dampfdruck	0.0000009 [mmHg]9.00X10-7 mm Hg @ 25 °C1.24×10-4 Pa (25 °C)
Physical Description	Profenofos is a pale yellow liquid with garlic-like odor. Corrosive. Used as an insecticide.Pale yellow or amber liquid with an odor like garlic[HSDB]
Stability/Shelf Life	Relatively stable under neutral & slightly acidic conditions. Unstable under alkaline conditions.
Kovats Retention Index	2153.82119.82123.521652174218421862160.621442165.82167.22153.621502133.6
Collision Cross Section	169.5 Å² [M+H]+ [CCS Type: DTBuffer gas: N2Ionization: ESI+Dataset: TOXCASTSource Identifier: DTXSID3032464]184.3 Å² [M+Na]+ [CCS Type: DT166.61 Å² [M+H]+ [CCS Type: TWIonization: GC-APCI+]182.33 Å² [M+Na]+166.64 Å² [M+H]+
Schmelzpunkt	<25 °C
Brechungsindex	n20D 1.5466
Flammpunkt	124℃
Lagerbedingungen	APPROX 4°C
Aggregatzustand	Oily Liquid
Farbe	Colorless to light yellow
Wichte	1.455 (20℃)
Merck	13,7860
BRN	2150258
Henry-Konstante	4.5×102 mol/(m3Pa) at 25℃, HSDB (2015)
Hauptanwendungen	agricultureenvironmental
InChI	1S/C11H15BrClO3PS/c1-3-7-18-17(14,15-4-2)16-11-6-5-9(12)8-10(11)13/h5-6,8H,3-4,7H2,1-2H3
InChIKey	QYMMJNLHFKGANY-UHFFFAOYSA-N
SMILES	CCCSP(=O)(OCC)Oc1ccc(Br)cc1Cl
LogP (Verteilungskoeffizient)	4.2 at 25℃
CAS Datenbank	41198-08-7(CAS DataBase Reference)
NIST chemische Informationen	Phosphorothioic acid, o-(4-bromo-2-chlorophenyl) o-ethyl s-propyl ester(41198-08-7)
EPA chemische Informationen	Profenofos (41198-08-7)

Sicherheit & Vorschriften

GHS-Einstufung	WarningH302: Harmful if swallowed [Warning Acute toxicity, oral]H312: Harmful in contact with skin [Warning Acute toxicity, dermal]H332: Harmful if inhaled [Warning Acute toxicity, inhalation]H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]H410: Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]P261, P264, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P317, P321, P330, P362+P364, P391, and P501 (click each P-code to see the statement)Danger
Regulatorische Informationen	Regulation (EC) No 1107/2009 (amended)Profenofos is listed in the dataset of EPA Human Health Benchmarks for Pesticides under the Safe Drinking Water Act (40 eCFR 141)2002/2076Status: Active Update: 17-01-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/16045
Weitere Sicherheitsinformationen	IMAP assessments - Phosphorothioic acid, O-(4-bromo-2-chlorophenyl) O-ethyl S-propyl ester: Environment tier I assessmentIMAP assessments - Phosphorothioic acid, O-(4-bromo-2-chlorophenyl) O-ethyl S-propyl ester: Human health tier I assessment
DOT-Kennzeichnung	Poison
Brandgefahren	Excerpt from ERG Guide 152 [Substances - Toxic (Combustible)]:Combustible material: may burn but does not ignite readily. Containers may explode when heated. Those substances designated with a (P) may polymerize explosively when heated or involved in a fire. Runoff may pollute waterways. Substance may be transported in a molten form. (ERG, 2024)
Gesundheitsgefahren	Excerpt from ERG Guide 152 [Substances - Toxic (Combustible)]:Highly toxic, may be fatal if inhaled, ingested or absorbed through skin. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause environmental contamination. (ERG, 2024)

Anwendungen & Verwendung

Beschreibung

Profenofos is a pale yellow liquid, bp 100 C/1.80 Pa, vp 0.124 mPa (25 C). Solubility in water is 28 mg/L (25 C). It is miscible with most organic solvents. Log Kow = 4.44. It is relatively stable in neutral and mild acid media but hydrolyzed in alkaline media; DT50 values (20 C) at pH 5, 7, and 9 are 93 d, 14.6 d, and 5.7 h, respectively.

Verwenden

Profenofos is used to control insects (particularly caterpillars and Lepidoptera eggs) and mites on cotton, maize, sugar beet, soyabean, potatoes, vegetables, tobacco and a number of other crops