calcein AM
Grundinformationen
- CAS
148504-34-1- Standard-SMILES
CC(=O)OCOC(=O)CN(CC(=O)OCOC(C)=O)Cc1cc2c(cc1OC(C)=O)Oc1cc(OC(C)=O)c(CN(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)cc1C21OC(=O)c2ccccc21- InChIKey
BQRGNLJZBFXNCZ-UHFFFAOYSA-N- Summenformel
- C46H46N2O23
- Durchschnittliche Molmasse
- 994,9 g/mol
- Monoisotopische Masse
- 994,24913572
Überblick
Calcein am is an organic heteropentacyclic compound that is calcein in which all four carboxy group hydrogens have been substituted by (acetyloxy)methoxy groups and the hyrodgens of the two hydroxy groups have been substituted by acetyl groups. It is a a non-fluorescent probe cleaved to a fluorescent probe by non-specific intracellular esterases. It has a role as a fluorochrome. It is a gamma-lactone, a xanthene dye, an oxaspiro compound, an organic heteropentacyclic compound, a member of 2-benzofurans and an acetate ester. It is functionally related to a calcein.
Namen und Bezeichner
- Bevorzugter Name
- calcein AM
- IUPAC
- acetyloxymethyl 2-[[2-(acetyloxymethoxy)-2-oxoethyl]-[[3',6'-diacetyloxy-7'-[[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]methyl]-3-oxospiro[2-benzofuran-1,9'-xanthene]-2'-yl]methyl]amino]acetate
- Englischer Name
- CALCEIN-AM
- Summenformel
- C46H46N2O23
- Molmasse
- 994.86
Namen und Synonyme
Calcein AM148504-34-1calcein-acetoxymethyl esteracetoxymethyl 2-[[2-(acetoxymethoxy)-2-oxo-ethyl]-[[3',6'-diacetoxy-7'-[[bis[2-(acetoxymethoxy)-2-oxo-ethyl]amino]methyl]-3-oxo-spiro[isobenzofuran-1,9'-xanthene]-2'-yl]methyl]amino]acetateDTXSID101043565CHEBI:3303acetoxymethyl 2-((2-(acetoxymethoxy)-2-oxo-ethyl)-((3',6'-diacetoxy-7'-((bis(2-(acetoxymethoxy)-2-oxo-ethyl)amino)methyl)-3-oxo-spiro(isobenzofuran-1,9'-xanthene)-2'-yl)methyl)amino)acetateRefChem:122727DTXCID601526081Glycine, N,N'-((3',6'-bis(acetyloxy)-3-oxospiro(isobenzofuran-1(3H),9'-(9H)xanthene)-2',7'-diyl)bis(methylene))bis(N-(2-((acetyloxy)methoxy)-2-oxoethyl))-, bis((acetyloxy)methyl) estercalcein-AMCalcein, AM
Weitere Namen anzeigen
Calcein AcetoxyMethyl EsterCAL-AMNSC 689290AM /Calcein-AMCAL-AMCalcein AM solutionCellstain- Calcein-AM-Cellstain-Calcein-AmSolutionCalcein, AM *CAS 148504-34-1*
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 2,9
- Polarare Oberfläche (TPSA)
- 305 Ų
- H-Brücken-Donoren
- 0
- H-Brücken-Akzeptoren
- 25
- Frei drehbare Bindungen
- 32
- Schwere Atome
- 71
- Formalladung
- 0
- Komplexität
- 1.810
Physikochemische Eigenschaften
- Schmelzpunkt
- 250 ℃ · >250℃
- Siedepunkt
- 982.7 · 982.7±65.0 °C(Predicted)
- Dichte
- 1.49 · 1.49±0.1 g/cm3(Predicted)
- Brechungsindex
- 20 · n20/D 1.479
- Flammpunkt
- 85 °C · 85 °C
- storage temp.
- -20 °C · -20°C
- Löslichkeit
- 10 mg/mL, · DMSO: soluble10mg/mL, clear, colorless to slightly yellow
- Aggregatzustand
- powder
- pka
- 2.66 · 2.66±0.50(Predicted)
- Farbe
- Colorless
- InChIKey
- BQRGNLJZBFXNCZ-UHFFFAOYSA-N
- SMILES
- C12(C3=C(C=C(OC(C)=O)C(CN(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)=C3)OC3=C1C=C(CN(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C(OC(C)=O)=C3)C1=C(C=CC=C1)C(=O)O2
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
Sicherheitsdaten
- F
- 10-21
- wgk
- 3
- ridadr
- NA 1993 / PGIII
- risk_code
- 36/37/38
- hazard_code
- Xi
- safety_code
- 26-36
- Speicherklasse
- 11 - Combustible Solids
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Substances that inhibit or prevent the proliferation of NEOPLASMS.
Chemicals that emit light after excitation by light. The wave length of the emitted light is usually longer than that of the incident light. Fluorochromes are substances that cause fluorescence in other substances, i.e., dyes used to mark or label other compounds with fluorescent tags.
Anwendungen
VerwendenCalcein-AM appears to best satisfy the criteria for assaying cell adhesion and to have the least effect on cell viability and cell functions.
Anbieter93 Anbieter
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
湖南韵邦生物科技股份有限公司0731-88532326 13319508186 · [email protected]
Hebei Chuanghai Biotechnology Co., Ltd+86-17732866630 · [email protected]
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
合肥翰刚医药科技有限公司+8618062405514 · [email protected]
咸宁深蓝生物医药研发有限公司18171815831 · [email protected]
上海优宁维生物科技股份有限公司15921930842 15921930842 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
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