2-((2,6-Dimethylphenyl)amino)-N,N,N-triethyl-2-oxoethanaminium
Grundinformationen
- CAS
21306-56-9- Standard-SMILES
CC[N+](CC)(CC)CC(=O)Nc1c(C)cccc1C- InChIKey
PYEBKOFMWAMBFV-UHFFFAOYSA-O- Summenformel
- C16H27N2O+
- Durchschnittliche Molmasse
- 263,4 g/mol
- Monoisotopische Masse
- 263,21233849
Überblick
QX-314 is a monocarboxylic acid amide. It has a role as a local anaesthetic.
Namen und Bezeichner
- Bevorzugter Name
- 2-((2,6-Dimethylphenyl)amino)-N,N,N-triethyl-2-oxoethanaminium
- IUPAC
- [2-(2,6-dimethylanilino)-2-oxoethyl]-triethylazanium
- Englischer Name
- QX-314
- Summenformel
- C16H27N2O+
- Molmasse
- 263.4
Namen und Synonyme
QX-314QX 31446ZIF6Y2X9CHEBI:469372-((2,6-Dimethylphenyl)amino)-N,N,N-triethyl-2-oxoethanaminium2-[(2,6-dimethylphenyl)amino]-N,N,N-triethyl-2-oxoethanaminiumDTXSID10943813(2-((2,6-dimethylphenyl)amino)-2-oxoethyl)-triethylazanium[2-[(2,6-dimethylphenyl)amino]-2-oxoethyl]-triethylazaniumRefChem:178402DTXCID50137217621306-56-9
Weitere Namen anzeigen
LIDOCAINE N-ETHYL BROMIDEQX-314.BrQX 314 BROMIDEQX 314, 10 mM in DMSOLidocaine N-ethyl bromidLidocaine N-ethyl bromideQX-314 - CAS 21306-56-9 - CalbiochemQX 314 BROMIDE,LIDOCAINE N-ETHYL BROMIDQX-314 bromide (N-Ethyllidocaine bromide)
N-ETHYLLIDOCAINE BROMIDECHEMBL128028Tocris-1014Lopac-L-5783UPCMLD-DP014UNII-46ZIF6Y2X9Lopac0_000679SCHEMBL93854
Datenbank-Bezeichner
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 2,5
- Polarare Oberfläche (TPSA)
- 29,1 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 1
- Frei drehbare Bindungen
- 6
- Schwere Atome
- 19
- Formalladung
- 1
- Komplexität
- 268
Physikochemische Eigenschaften
- Schmelzpunkt
- 220 · 220 - 222°C
- storage temp.
- Desiccate at RT
- Löslichkeit
- DMSO (Slightly), Methanol (Slightly)
- Aggregatzustand
- lyophilized solid
- Farbe
- White to Off-White
- Wasserlöslichkeit
- 3 mg/mL · water: 3mg/mL
- Specific Activity
- 40 · 40-60 Ci/mmol
- Major Application
- forensics and toxicologypharmaceutical (small molecule)veterinary
- InChI
- 1S/C16H26N2O.BrH/c1-6-18(7-2,8-3)12-15(19)17-16-13(4)10-9-11-14(16)5;/h9-11H,6-8,12H2,1-5H3;1H
- InChIKey
- DLHMKHREUTXMCH-UHFFFAOYSA-N
- SMILES
- [Br-].CC[N+](CC)(CC)CC(=O)Nc1c(C)cccc1C
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 38 reports by companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Sicherheitsdaten
- wgk
- 3
- risk_code
- 36/37/38
- hazard_code
- Xi
- safety_code
- 26-36
- Speicherklasse
- 11 - Combustible Solids
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.
Anwendungen
VerwendenBlocker of voltage-activated sodium channels
Anbieter30 Anbieter
陕西缔都医药有限责任公司029-81124775 17791530730 · [email protected]
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
上海优宁维生物科技股份有限公司15921930842 15921930842 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
欧利希（湖北）医药科技有限公司17316404525 17316404525 · [email protected]
怀化市冰峰化工有限公司0745-2866851 17711757908 · [email protected]
Ascent Scientific4401179829988 · [email protected]
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