1-Methyl-4-phenylpyridinium

1-Methyl-4-phenylpyridinium · 1-methyl-4-phenyl-pyridine · N-methyl-4-phenylpyridinium · 1-Methyl-4-phenylpyridinium ion · 1-Methyl-4-phenylpyridinium chloride · 1 Methyl 4 phenylpyridinium chloride · 1-methyl-4-phenylpyridin-1-ium chloride

https://huagongshe.com/de/chemical/39484

Molekülstruktur von 1-Methyl-4-phenylpyridinium

Identifikatoren & physikalische Daten

CAS No.	48134-75-4
Summenformel	C12H12N+
Durchschnittliche Molmasse	170,23 g/mol
Monoisotopische Masse	170,09697439 g/mol
SMILES	C[n+]1ccc(-c2ccccc2)cc1
InChIKey	FMGYKKMPNATWHP-UHFFFAOYSA-N
PubChem CID	39484
ChEMBL	CHEMBL311617
ChEBI	CHEBI:641
DTXSID	DTXSID4058106

Chemische & physikalische Eigenschaften

XLogP	2,7
Polarare Oberfläche (TPSA)	3,9
H-Brücken-Donoren	0
H-Brücken-Akzeptoren	0
Frei drehbare Bindungen	1
Schwere Atome	13
Formalladung	1
Komplexität	141
EPA chemische Informationen	Cyperquat (48134-75-4)

Sicherheit & Vorschriften

Toxizität	The proximal toxicant formed when MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is metabolized by monoamine oxidase B. Unlike MPTP, this compound will not pass the blood-brain barrier, but it is a substrate for the dopamine neurotransporter, and thus is able to enter dopamine neurons. It is believed to destroy dopamine neurons by mechanisms involving both free radical production and inhibition of mitochondrial electron transport.

Toxizität

The proximal toxicant formed when MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is metabolized by monoamine oxidase B. Unlike MPTP, this compound will not pass the blood-brain barrier, but it is a substrate for the dopamine neurotransporter, and thus is able to enter dopamine neurons. It is believed to destroy dopamine neurons by mechanisms involving both free radical production and inhibition of mitochondrial electron transport.