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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HCID 39765Erstellt: 2. November 2026

Vecuronium

BGSZAXLLHYERSY-XQIGCQGXSA-N · 1-[(2β,3α,5α,16β,17β)-3,17-Bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium · Piperidinium, 1-[(2b,3a,5a,16b,17b)-3,17-bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methyl- (9CI)

https://huagongshe.com/de/chemical/39765

Molekülstruktur von Vecuronium

Identifikatoren & physikalische Daten

CAS No.50700-72-6
SummenformelC34H57N2O4+
Durchschnittliche Molmasse557,8 g/mol
Monoisotopische Masse557,4318333 g/mol
SMILESCC(=O)O[C@H]1C[C@@H]2CC[C@@H]3[C@H](CC[C@@]4(C)[C@H]3C[C@H]([N+]3(C)CCCCC3)[C@@H]4OC(C)=O)[C@@]2(C)C[C@@H]1N1CCCCC1
InChIKeyBGSZAXLLHYERSY-XQIGCQGXSA-N
PubChem CID39765
ChEMBLCHEMBL1201219
ChEBICHEBI:9939
DTXSIDDTXSID1044146

Chemische & physikalische Eigenschaften

XLogP6,5
Polarare Oberfläche (TPSA)55,8
H-Brücken-Donoren0
H-Brücken-Akzeptoren5
Frei drehbare Bindungen6
Schwere Atome40
Formalladung1
Komplexität958
ArzneimittelPharmaceuticals -> Listed in ZINC15
Löslichkeit1.86e-05 g/L
Human DrugsBreast FeedingLactationMuscle RelaxantsNeuromuscular Nondepolarizing AgentsMuscle relaxants (peripherally-acting) and cholinesterase inhibitors
Physical DescriptionSolid
Collision Cross Section246.83 Ų [M]+ [CCS Type: TWMethod: calibrated with polyalanine and drug standards]

Sicherheit & Vorschriften

Unerwünschte WirkungenThe primary adverse event associated with all nondepolarizing neuromuscular agents is the extension of the drug's pharmacological effect past the needed time of use, resulting in adverse effects ranging from skeletal muscle weakness to extended muscular paralysis leading to respiratory insufficiency or apnea.
ToxizitätsübersichtThe risk of iatrogenic overdosage can be reduced by closely monitoring muscle twitch responses using peripheral nerve stimulation. Anticholinesterases antagonize neuromuscular blockade actiontherefore, acetylcholinesterase inhibitors such as neostigmine are useful to reverse rocuronium and vecuronium's effect on muscle paralysis.
Drug Induced Liver InjuryDrug-Induced Liver Injury Severity and Toxicity (DILIst)vecuroniumDILI NegativeIntravenousDOI:10.1016/j.drudis.2019.09.022
Effects During Pregnancy and Lactation◉ Summary of Use during Lactation