HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Phenazepam
CJC-1295 with DAC · PHENAZEPAM · bd98 · fenazepam · Phenazapam · PHENATZEPAM · Phenazepam (CRM) · IFLAB-BB F0133-0017
Identifikatoren & physikalische Daten
| CAS No. | 51753-57-2 |
|---|---|
| Summenformel | C15H10BrClN2O |
| Durchschnittliche Molmasse | 349,61 g/mol |
| Monoisotopische Masse | 347,9665 g/mol |
| SMILES | O=C1CN=C(c2ccccc2Cl)c2cc(Br)ccc2N1 |
| InChIKey | CGMJQQJSWIRRRL-UHFFFAOYSA-N |
| PubChem CID | 40113 |
| ChEMBL | CHEMBL1709464 |
| EC No. | 682-231-2 |
| DTXSID | DTXSID00199685 |
Chemische & physikalische Eigenschaften
| XLogP | 3,3 |
|---|---|
| Polarare Oberfläche (TPSA) | 41,5 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 1 |
| Schwere Atome | 20 |
| Formalladung | 0 |
| Komplexität | 415 |
| Arzneimittel | DEA NFLIS-Drug Category -> BenzodiazepinesPharmaceuticals -> Synthetic Cannabinoids or Psychoactive Compounds |
| LogP (Verteilungskoeffizient) | 3.3 |
| Collision Cross Section | 166 Ų [M+H]+ [CCS Type: TWMethod: Major Mix IMS/Tof Calibration Kit (Waters)] |
| Schmelzpunkt | 214-224°C |
| Siedepunkt | 493.0±45.0 °C(Predicted) |
| Dichte | 1.61±0.1 g/cm3(Predicted) |
| Flammpunkt | 2℃ |
| Lagerbedingungen | Controlled Substance, -20°C Freezer |
| Löslichkeit | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| Aggregatzustand | Solid |
| pKa (Säurekonstante) | 11.58±0.70(Predicted) |
| Farbe | Pale Yellow |
| Hauptanwendungen | clinical testing |
| InChI | 1S/C15H10BrClN2O/c16-9-5-6-13-11(7-9)15(18-8-14(20)19-13)10-3-1-2-4-12(10)17/h1-7H,8H2,(H,19,20) |
| InChIKey | CGMJQQJSWIRRRL-UHFFFAOYSA-N |
| SMILES | Clc1ccccc1C2=NCC(=O)Nc3ccc(Br)cc23 |
| CAS Datenbank | 51753-57-2(CAS DataBase Reference) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH319 (95.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]P203, P260, P263, P264, P264+P265, P270, P280, P305+P351+P338, P318, P337+P317, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 42 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Hazard Classes and Categories | Eye Irrit. 2 (95.2%) |
| Wassergefährdungsklasse (WGK) | 2 |
| UN-Transportnummer | UN 1648 3 / PGII |
| R-Sätze (R) | 11-20/21/22-36 |
| Toxizität | LD50 ipr-rat: 720 mg/kg KHFZAN 13(10),108,79 |
| Gefahrensymbole | F,Xn |
| Sicherheitshinweise (S) | 16-36/37 |
| Lagerklasse | 3 - Flammable liquids |
| Gefahrenklasse | Acute Tox. 4 DermalAcute Tox. 4 InhalationAcute Tox. 4 OralEye Irrit. 2Flam. Liq. 2Muta. 1B |
Anwendungen & Verwendung
Beschreibung
Phenazepam (CRM) (Item No. ISO60172) is a certified reference material categorized as a benzodiazepine. It has sedative and hypnotic properties and has been detected in illicit tablets. This product is intended for research and forensic applications.
Verwenden
7-Bromo-5-(2-chlorophenyl)-1,3-dihydro-2H-1,4-Benzodiazepin-2-one is used in the treatment of neurological disorders such as epilepsy, alcohol withdrawal and insomnia. It can be used as a premedication before surgery as it augments the effects of anesthetics and reduces anxiety