Methyl 2-azidoacetate

HCID 4020482CAS 1816-92-8

Teilstruktursuche Ähnliche Strukturen suchen

Grundinformationen

Standard-SMILES: COC(=O)CN=[N+]=[N-]
InChIKey: RXYCUKSOYJWGPE-UHFFFAOYSA-N
Summenformel: C3H5N3O2
Durchschnittliche Molmasse: 115,09 g/mol
Monoisotopische Masse: 115,0381764

Namen und Bezeichner

Bevorzugter Name: Methyl 2-azidoacetate
IUPAC: methyl 2-azidoacetate
Englischer Name: Azidoacetic acid methyl ester
Summenformel: C3H5N3O2
Molmasse: 115.0907

Namen und Synonyme

Methyl 2-azidoacetate1816-92-8DTXSID70398587RefChem:1089321DTXCID00349446Methyl azidoacetateMETHYLAZIDOACETATEMFCD01311034Acetic acid, 2-azido-, methyl estermethyl 3-diazo-3-azaprop-3-enoateAzidoacetic acid methyl esterAcetic acid, azido-, methyl ester

Weitere Namen anzeigen

Methyl 2-azidoacetate 97%Methyl Azido Acetate-BulkMethyl 2-azidoacetate - M34612-Azido-acetic acid Methyl ester

azido-acetic acid methyl esterAzidoacetic acid, methyl estermethyl azido acetatemethyl azido-acetatemethyl-2-azidoacetateMethyl 2-azidoacetate, 97%SCHEMBL13482799SBB001917

Datenbank-Bezeichner

CAS: 1816-92-8
PubChem CID: 4020482
DTXSID: DTXSID70398587
EC Number: 687-878-4
Nikkaji: J1.247.582I

Eigenschaften

Berechnete Struktureigenschaften

XLogP: 1,2
Polarare Oberfläche (TPSA): 40,7 Å²
H-Brücken-Donoren: 0
H-Brücken-Akzeptoren: 4
Frei drehbare Bindungen: 3
Schwere Atome: 8
Formalladung: 0
Komplexität: 126

Physikochemische Eigenschaften

Siedepunkt: 35 °C · 35 °C
Dichte: 1.182 g/mL · 1.182 g/mL at 25 °C
Brechungsindex: 20 · n20/D1.440
Flammpunkt: 48 ℃ · 48℃
Aggregatzustand: liquid
InChI: InChI=1S/C3H5N3O2/c1-8-3(7)2-5-6-4/h2H2,1H3
InChIKey: RXYCUKSOYJWGPE-UHFFFAOYSA-N
SMILES: C(=O)(OC)CN=[N+]=[N-]

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 4 Einträge

Warning

H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]

P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Hazard Classes and CategoriesFlam. Liq. 3 (100%)

Sicherheitsdaten

wgk: 3
ridadr: UN 1993C 3 / PGIII
risk_code: 5-10-36/37/38
hazard_code: Xi
safety_code: 26
hazard_class: 3
Speicherklasse: 3 - Flammable liquids
Hazard Classifications: Eye Irrit. 2Flam. Liq. 3Skin Irrit. 2STOT SE 3

Chemie und Industrie

Anwendungen · 1 Eintrag

VerwendenMethyl 2-azidoacetate is widely used as a precursor to build triazole derivatives via alkyne-azide click chemistry. Some of the examples include the synthesis of coumarin-triazole derivatives as potential antiplasmodial agents and macrocyclic triazole containing largazole analogs as histone deacetylases-1 (HDAC1) inhibitors.It can be used to synthesize various pyrrole derivatives by Knoevenagel condensation as in the synthesis of near-infrared boron dipyrromethene (BODIPY) donors for organic tandem solar cells.It can also be used in Hemetsberger-Knittel synthesis of substituted 5-, 6-, and 7-azaindoles.Synthesis of highly fluorescent pyreno[2,1-b]pyrroles using methyl 2-azidoacetate as one of the reagents.