HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Mecamylamin
Mekamine · Mevasine · Mecamine · Revetina · Plegangin · Revertina · MECAMYLAMINE BASE · N-Methyl-2-isocamphanamine
Identifikatoren & physikalische Daten
| CAS No. | 60-40-2 |
|---|---|
| Summenformel | C11H21N |
| Durchschnittliche Molmasse | 167,29 g/mol |
| Monoisotopische Masse | 167,16739967 g/mol |
| SMILES | CNC1(C)C2CCC(C2)C1(C)C |
| InChIKey | IMYZQPCYWPFTAG-UHFFFAOYSA-N |
| PubChem CID | 4032 |
| ChEMBL | CHEMBL267936 |
| ChEBI | CHEBI:6706 |
| EC No. | 200-476-1 |
| DTXSID | DTXSID0023240 |
| Lokaler Name | Mecamylamin |
Chemische & physikalische Eigenschaften
| XLogP | 2,6 |
|---|---|
| Polarare Oberfläche (TPSA) | 12 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 1 |
| Frei drehbare Bindungen | 1 |
| Schwere Atome | 12 |
| Formalladung | 0 |
| Komplexität | 197 |
| LogP (Verteilungskoeffizient) | 2.7 |
| Löslichkeit | 1.24e-01 g/L |
| Human Drugs | Pharmaceuticals |
| Schmelzpunkt | < 25 °C245-256℃ |
| Physical Description | Solid |
| Siedepunkt | 189℃ |
| Dichte | 0.91 |
| Brechungsindex | 1.4875 |
| Flammpunkt | 58℃ |
| EPA chemische Informationen | Bicyclo[2.2.1]heptan-2-amine, N,2,3,3-tetramethyl- (60-40-2) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory. |
|---|---|
| Hazard Classes and Categories | Acute Tox. 4 (100%) |
| Drug Induced Liver Injury | Drug-Induced Liver Injury Severity and Toxicity (DILIst)mecamylamineDILI NegativeOralDOI:10.1016/j.drudis.2019.09.022 |
| Alarmwort | Warnung |
| Gefahrenhinweise | Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H302 |
Anwendungen & Verwendung
Verwenden
Antihypertensive.