Phosphonsure
Phosphorous acid · PHOSPHONIC ACID · PHOSPHORUS ACID · Phosphorous acid 99% · Phosphonsure · Phospohorous acid · Phosphorous Acid Crystal · Phosphorous acid, extra pure, 98%
Identifikatoren & physikalische Daten
| CAS No. | 13598-36-2 |
|---|---|
| Summenformel | H3O3P |
| Durchschnittliche Molmasse | 81,996 g/mol |
| Monoisotopische Masse | 81,98198095 g/mol |
| SMILES | O=[PH](O)O |
| InChIKey | ABLZXFCXXLZCGV-UHFFFAOYSA-N |
| PubChem CID | 407 |
| ChEMBL | CHEMBL1235291 |
| EC No. | 237-066-7 |
| DTXSID | DTXSID2049715 |
| Lokaler Name | Phosphonsure |
Chemische & physikalische Eigenschaften
| XLogP | -1,6 |
|---|---|
| Polarare Oberfläche (TPSA) | 57,5 |
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 3 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 4 |
| Formalladung | 0 |
| Komplexität | 26 |
| Physical Description | Dry PowderLiquidLarge CrystalsCBI |
| Schmelzpunkt | 73 °C |
| Siedepunkt | 200 °C |
| Dichte | 1.651 g/mL at 25 °C(lit.) |
| Dampfdruck | 0.001Pa at 20℃ |
| Flammpunkt | 200°C |
| Lagerbedingungen | 0-6°C |
| Löslichkeit | DMSO (Slightly), Methanol (Slightly), Water (Sparingly)SOLUBLE |
| Aggregatzustand | Crystals |
| pKa (Säurekonstante) | pK1 1.29pK2 6.74(at 25℃) |
| Wichte | 1.651 |
| Farbe | White |
| pH | pKa1= 1.10, pKa2 = 6.33(25℃) |
| Merck | 14,7346 |
| Stabilität | Stable. Incompatible with strong bases. Hygroscopic. |
| InChI | 1S/H3O3P/c1-4(2)3/h4H,(H2,1,2,3) |
| InChIKey | ABLZXFCXXLZCGV-UHFFFAOYSA-N |
| SMILES | [H]P(O)(O)=O |
| CAS Datenbank | 13598-36-2(CAS DataBase Reference) |
| NIST chemische Informationen | (HO)2HPO(13598-36-2) |
| EPA chemische Informationen | Phosphonic acid (13598-36-2) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH302: Harmful if swallowed [Warning Acute toxicity, oral]H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]P260, P264, P270, P280, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P330, P363, P405, and P501 (click each P-code to see the statement)This chemical does not meet GHS hazard criteria for 0.1% (2 of 1718) of reports. |
|---|---|
| Regulatorische Informationen | Chemical: Phosphonic acidCommission Regulation No 844/2012Phosphonic acid is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Phosphonic acid are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 16-02-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/15806Ortho phosphorous acid: Does not have an individual approval but may be used under an appropriate group standardThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| Weitere Sicherheitsinformationen | IMAP assessments - Phosphonic acid: Human health tier II assessmentIMAP assessments - Phosphonic acid: Environment tier I assessment |
| EPA Safer Chemical | Chemical: Phosphonic acidYellow triangle - The chemical has met Safer Choice Criteria for its functional ingredient-class, but has some hazard profile issues. Specifically, a chemical with this code is not associated with a low level of hazard concern for all human health and environmental endpoints. (See Safer Choice Criteria). While it is a best-in-class chemical and among the safest available for a particular function, the function fulfilled by the chemical should be considered an area for safer chemistry innovation. |
| Hazard Classes and Categories | Met. Corr. 1 (22.3%)Acute Tox. 4 (98.6%)Skin Corr. 1 (99.9%)Eye Dam. 1 (47.1%)STOT SE 3 (26%)Acute toxicity - category 4Skin corrosion - category 1ASelf-reactive substances and mixtures - Type GAcute toxicity (Oral) - Category 4Skin corrosion/irritation - Category 1Serious eye damage/eye irritation - Category 1CorrosivesAcute Tox. 4 *Skin Corr. 1A |
| Protective Action Criteria (PAC) | 5.7 [mg/m3]63 [mg/m3]380 [mg/m3] |
| F | 3 |
| Wassergefährdungsklasse (WGK) | 1 |
| TSCA-Inventar-Status | TSCA listed |
| UN-Transportnummer | UN 2834 |
| Zollcode | 28092019 |
| RTECS-Nr. | SZ6400000 |
| R-Sätze (R) | 22-35 |
| Gefahrensymbole | C |
| Sicherheitshinweise (S) | 26-36/37/39-45 |
| Gefahrenklasse | 8Acute Tox. 4 OralEye Dam. 1Met. Corr. 1Skin Corr. 1A |
| Verpackungsgruppe | III |
| Lagerklasse | 8A - Combustible corrosive hazardous materials |
Anwendungen & Verwendung
Beschreibung
Phosphorous acid, H3PO3, is diprotic (readily ionizes two protons), not triprotic as might be suggested by this formula. Phosphorous acid is as an intermediate in the preparation of other phosphorous compounds. Because preparation and uses of “phosphorous acid” actually pertain more to the major tautomer, phosphonic acid, it is more often referred to as “phosphorous acid”. Phosphorous acid has the chemical formula H3PO3, which is best expressed as HPO(OH)2 to show its diprotic character. P(OH)3 (IUPAC: phosphorous acid) has CAS number 10294-56-1. It has been shown to be a stable tautomer.
Verwenden
Phosphorous acid is used to produce the fertilizer phosphate salt like potassium phosphite, ammonium phosphite and calcium phosphite. It is actively involved in the preparation of phosphites like aminotris(methylenephosphonic acid) (ATMP), 1-hydroxyethane 1,1-diphosphonic acid (HEDP) and 2-phosphonobutane-1,2,4-tricarboxylic Acid (PBTC), which find application in water treatment as a scale or corrosive inhibitor. It is also used in chemical reactions as a reducing agent. Its salt, lead phosphite is used as PVC stabilizer. It is also used as a precursor in the preparation of phosphine and as an intermediate in the preparation of other phosphorus compounds.
Herstellung & Synthese
synthetische
Phosphorus acid can be prepared by the reaction of phosphorus trichloride with water: PCl3 + 3H2O → H3PO4 + 3HClThe reaction is violent. Addition of PCl3 should be extremely cautious and slow. The addition can be carried out safely in the presence of concentrated HCl. Alternatively, a stream of air containing PCl3 vapor is passed into icecold water and solid crystals of H3PO4 form. Alternatively, phosphorus acid can be prepared by adding phosphorus trichloride to anhydrous oxalic acid: PCl3 + 3(COOH）2 → H3PO3 + 3CO + 3CO2 + 3HCl In this reaction, all products except H3PO3 escape as gases leaving the liquid acid. Dissolution of phosphorus sesquioxide in water also forms phosphorus acid. When shaken with ice water, phosphorus acid is the only product . P4O6 + 6H2O → 4H3PO3 However, in hot water part of the phosphorus acid disproportionates to phosphoric acid and phosphorus or phosphine.