Grundinformationen
- CAS
55-40-3- Standard-SMILES
CC(N)(Cc1ccc(O)c(O)c1)C(=O)O- InChIKey
CJCSPKMFHVPWAR-UHFFFAOYSA-N- Summenformel
- C10H13NO4
- Durchschnittliche Molmasse
- 211,21 g/mol
- Monoisotopische Masse
- 211,0844579
Überblick
3-Hydroxy-alpha-methyl-DL-tyrosine is a member of benzenes and a monocarboxylic acid.
Namen und Bezeichner
- Bevorzugter Name
- Alpha-methyldopa
- IUPAC
- 2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid
- Lokaler Name
- 3-Hydroxy-α-methyl-DL-tyrosin
- Englischer Name
- 3-Hydroxy-alpha-methyl-DL-tyrosine
- Summenformel
- C10H13NO4
- Molmasse
- 211.21
Namen und Synonyme
MulfasinMetholesalpha-MethyldopaEINECS 209-088-7EINECS 200-232-4LMethyldopaalphaMethylLdopaLalphaMethyldopa()MethyldopaL(alphaMd)RefChem:5558743HydroxyalphamethylLtyrosine
Weitere Namen anzeigen
MethydopaDL-METHYLDOPADL-A-METHYL DOPATIMTEC-BB SBB000508DL-ALPHA-METHYL-DOPA(rs)-alpha-methyldopa(+-)-alpha-methyldoparacemicalpha-methyldopa
alphaMethylL3,4dihydroxyphenylalanineLalphaMethyl3,4dihydroxyphenylalanine3(3,4Dihydroxyphenyl)2methylLalanineL()3(3,4Dihydroxyphenyl)2methylalaninealphaMethylbeta(3,4dihydroxyphenyl)LalanineL()alphaMethylbeta(3,4dihydroxyphenyl)alanineL()beta(3,4Dihydroxyphenyl)alphamethylalanineL2Amino2methyl3(3,4dihydroxyphenyl)propionic acid
Datenbank-Bezeichner
- CAS
55-40-3、555-29-3、555-30-6- PubChem CID
- 4138
- DTXSID
DTXSID60970356
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- -1,9
- Polarare Oberfläche (TPSA)
- 104 Ų
- H-Brücken-Donoren
- 4
- H-Brücken-Akzeptoren
- 5
- Frei drehbare Bindungen
- 3
- Schwere Atome
- 15
- Formalladung
- 0
- Komplexität
- 246
Experimentelle und physikochemische Eigenschaften
Chemical ClassesOther Uses -> Pharmaceuticals
Human DrugsBreast Feeding; Lactation; Milk, Human; Antihypertensive Agents; Adrenergic alpha-2 Receptor Agonists
Dissociation Constants2.21
Physikochemische Eigenschaften
- storage temp.
- 20 °C · −20°C
- CAS Datenbank
- 555 · 555-29-3(CAS DataBase Reference)
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Warning
H315 (19.1%): Causes skin irritation [Warning Skin corrosion/irritation]
P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364 (click each P-code to see the statement)
Aggregated GHS information provided per 47 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Hazards Summary
Asthma reported in the pharmaceutical industry; [Malo] As an oral medication, methyldopa is used to treat hypertension. Many side effects have been reported after ingestion of therapeutic doses, including immune hemolytic anemia and drug-induced hepatitis. [HSDB]
Hazard Classes and CategoriesSkin Irrit. 2 (19.1%)
Toxikologische Informationen
Adverse EffectsOccupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.
Effects During Pregnancy and Lactation◉ Summary of Use during Lactation
Sicherheitsdaten
- wgk
- 3
- risk_code
- 36
- hazard_code
- Xi
- safety_code
Chemie und Industrie
Pharmakologische Informationen
ATC Code
C - Cardiovascular system
QC - Cardiovascular system
Vor- und nachgelagerte Produkte
Nachgelagerte Produkte
Anbieter27 Anbieter
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