Reaktionsgemisch, bestehend aus5-Chlor-2-methyl-2H-isothiazol-3-on und 2-Methyl-2H-isothiazol-3-on (3:1)

Kathon

HCID 41679CAS 55965-84-9
TeilstruktursucheÄhnliche Strukturen suchen

Grundinformationen

Standard-SMILES
Cn1sc(Cl)cc1=O.Cn1sccc1=O
InChIKey
QYYMDNHUJFIDDQ-UHFFFAOYSA-N
Summenformel
C8H9ClN2O2S2
Durchschnittliche Molmasse
264,8 g/mol

Überblick

industrial biocide & cosmetic preservative formulation; contains methylcholoro-isothiazolinone and methylcholoroisothiazolinone

Namen und Bezeichner

Bevorzugter Name
Kathon
IUPAC
5-chloro-2-methyl-1,2-thiazol-3-one;2-methyl-1,2-thiazol-3-one
Lokaler Name
Reaktionsgemisch, bestehend aus5-Chlor-2-methyl-2H-isothiazol-3-on und 2-Methyl-2H-isothiazol-3-on (3:1)
Englischer Name
Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT)
Summenformel
C4H5NOS.C4H4ClNOS
Molmasse
264.75

Namen und Synonyme

55965-84-9Kathon 886Kathon LX15O9QS218W3(2H)-Isothiazolone, 5-chloro-2-methyl-, mixt. with 2-methyl-3(2H)-isothiazoloneKathon 886 biocideMBC-215RefChem:151011KathonKathon biocideKathon CGKathon 886MW
Weitere Namen anzeigen
Isothiazolinone chloride5-Chloro-2-methyl-3(2H)-isothiazolone with 2-methyl-3(2H)-isothiazoloneCon WTNeoCideSidchem 715CMIT/MIT 1.5CGCMIT/MIT B/PLUSCMI/MI Kathon 886
Zonen FProClin 3002-Methylisothiazol-3(2H)-one compound with 5-chloro-2-methylisothiazol-3(2H)-one(14%in H2O)2-Methylisothiazol-3(2H)-one compound with 5-chloro-2-methylisothiazol-3(2H)-one5-chloro-2-methyl-1,2-thiazol-3-one;2-methyl-1,2-thiazol-3-oneBio-Perge5-Chloro-2-methyl-3(2H)-isothiazolone mixt. with 2-methyl-3(2H)-isothiazoloneKathon WT

Datenbank-Bezeichner

CAS
55965-84-9
PubChem CID
41679
ChEMBL
CHEMBL108095
EC Number
611-341-5、911-418-6、932-593-5

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA)
91,2 Ų
H-Brücken-Donoren
0
H-Brücken-Akzeptoren
4
Frei drehbare Bindungen
0
Schwere Atome
15

Experimentelle und physikochemische Eigenschaften

FragrancesFragrance Ingredient (3(2H)_-_Isothiazolone, 5-_chloro-_2-_methyl-_, mixt. with 2-_methyl-_3(2H)_-_isothiazolone) -> IFRA transparency List
Food Contact SubstancesFCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR
Physical DescriptionLiquid

Physikochemische Eigenschaften

Siedepunkt
100.1 ℃ · 100.1℃ at 101.325kPa
Dichte
20 · d20 1.19
Dampfdruck
0.003 · 0.003-17Pa at 20-45℃
storage temp.
Sealed in dry,Room Temperature
Löslichkeit
Chloroform (Soluble), DMSO (Slightly), Methanol (Slightly), Water
Aggregatzustand
Liquid

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

Danger

H301: Toxic if swallowed [Danger Acute toxicity, oral]

P260, P261, P262, P264, P264+P265, P270, P271, P272, P273, P280, P284, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P320, P321, P330, P333+P317, P361+P364, P362+P364, P363, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

This chemical does not meet GHS hazard criteria for < 0.1% (1 of 1945) of reports.

Danger

H301 (99.8%): Toxic if swallowed [Danger Acute toxicity, oral]

Gefahrenhinweise

Regulatory Information · 3 Einträge

3(2H)-Isothiazolone, 5-chloro-2-methyl-, mixt. with 2-methyl-3(2H)-isothiazolone is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 3(2H)-Isothiazolone, 5-chloro-2-methyl-, mixt. with 2-methyl-3(2H)-isothiazolone are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 14-03-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/23870

Mixture of methylchloroisothiazolinone and methylisothiazolinone: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationPEC / SN / Other assessments - Common skin sensitisers—hazard classification: Health
Hazard Classes and Categories · 5 Einträge

Acute Tox. 3 (99.8%)

Acute Tox. 3 (100%)

Acute Tox. 4 (100%)

Acute toxicity (inhalation) - category 2

Acute Tox. 2

Sicherheitsdaten

Toxizität
LD50 (mg/kg) orally in rabbits: 30; i.p. in male, female rats: 4.6, 4.3; LC50 (6 day) in trout, sunfish (mg/l): 0.14, 0.54; LC50 (8 day dietary) in Bobwhite quail, Peking duck (mg/kg/day): >60, >100 (J. Am. Coll. Toxicol.)

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological ClassificationChemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes.

Verwendung und Herstellung

U.S. Production2023: <50,000 lb
Consumer UsesNot Known or Reasonably Ascertainable
Industry UsesNot Known or Reasonably Ascertainable
Household ProductsInformation on 63 consumer products that contain Kathon biocide in the following categories is provided:
Use ClassificationFragrance Ingredients
General Manufacturing InformationNot Known or Reasonably Ascertainable
Anwendungen · 2 Einträge

BeschreibungKathon 886 metalwork fluid is a mixture of the two isothiazoliones contained in Kathon CG, at a 13.9% concentration. It is mainly contained in metalwork fluids. As an active component of Aigezid Ⅱ and contained in a water bath used for phtotographic development, it caused contact dermatitis in a photograph developer.

VerwendenAntimicrobial preservative in cosmetics, hygeine products, paints, emulsions, cutting oils, paper coatings, and water storage and cooling units.

Vor- und nachgelagerte Produkte

Vorgelagerte Rohstoffe

Anbieter50 Anbieter

郑州阿尔法化工有限公司+86-18530059196 · [email protected]
湖北永阔科技有限公司027-59223108 15972152991 · [email protected]
湖北万得化工有限公司15377098680 15377098680 · [email protected]
南通润丰石油化工有限公司66017690 19952660367 · [email protected]
武汉欣扬瑞和化学科技有限公司13720274133 · [email protected]

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