HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Dihydrolipoic Acid
DHLA · dihydrolipoate · LIPOIC ACID, REDUCED · 6,8-DIMERCAPTO-OCTANOIC ACID · usafxr-12 · USAF XR-12 · Dihydroliponsure · reducedlipoicacid
Identifikatoren & physikalische Daten
| CAS No. | 462-20-4 |
|---|---|
| Summenformel | C8H16O2S2 |
| Durchschnittliche Molmasse | 208,3 g/mol |
| Monoisotopische Masse | 208,05917175 g/mol |
| SMILES | O=C(O)CCCCC(S)CCS |
| InChIKey | IZFHEQBZOYJLPK-UHFFFAOYSA-N |
| PubChem CID | 421 |
| ChEMBL | CHEMBL1235647 |
| ChEBI | CHEBI:18047 |
| EC No. | 610-288-5 |
| DTXSID | DTXSID50861946 |
Chemische & physikalische Eigenschaften
| XLogP | 1,8 |
|---|---|
| Polarare Oberfläche (TPSA) | 39,3 |
| H-Brücken-Donoren | 3 |
| H-Brücken-Akzeptoren | 4 |
| Frei drehbare Bindungen | 7 |
| Schwere Atome | 12 |
| Formalladung | 0 |
| Komplexität | 128 |
| Physical Description | Solid |
| Schmelzpunkt | 62 °C |
| Siedepunkt | 161.5 °C(Press: 0.7 Torr) |
| Dichte | 1.132 g/cm3 |
| Dampfdruck | 0Pa at 25℃ |
| Brechungsindex | 1.5220-1.5260 |
| Lagerbedingungen | +2C to +8C |
| Löslichkeit | Chloroform (Slightly), Methanol (Slightly) |
| Aggregatzustand | liquid |
| pKa (Säurekonstante) | 4.74±0.10(Predicted) |
| Farbe | light yellow |
| InChI | InChI=1S/C8H16O2S2/c9-8(10)4-2-1-3-7(12)5-6-11/h7,11-12H,1-6H2,(H,9,10) |
| InChIKey | IZFHEQBZOYJLPK-UHFFFAOYSA-N |
| SMILES | C(O)(=O)CCCCC(S)CCS |
| LogP (Verteilungskoeffizient) | 1.9 at 20℃ |
| Oberflächenspannung | 53.6mN/m at 1.02g/L and 21℃ |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 41 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | Status: Active Update: 26-03-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/11996 |
| Hazard Classes and Categories | Skin Irrit. 2 (100%) |
| Wassergefährdungsklasse (WGK) | 3 |
| Zollcode | 2930.90.4950 |
| RTECS-Nr. | RH0525000 |
| R-Sätze (R) | 36/37/38 |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 26-36 |
| Lagerklasse | 10 - Combustible liquids |
| Gefahrenklasse | Acute Tox. 4 OralAquatic Chronic 2Eye Dam. 1Skin Irrit. 2Skin Sens. 1 |
Anwendungen & Verwendung
Verwenden
γ-Lipoic Acid, is a metabolite of α-Lipoic Acid (L468730), which is a over-the-counter nutritional supplements, that has been used as antioxidant. It is also fat-metabolism stimulator, and thus used a "weight loss" and "energy" supplement.