2-nitromethylenetetrahydro-2H-1,3-thiazine

nithiazine · SD 35651 · (2E)-2-(nitromethylidene)-1,3-thiazinane · tetrahydro-2-(nitromethylene)-2H-1,3-thiazine · 2H-1,3-Thiazine, tetrahydro-2-(nitromethylene)-

https://huagongshe.com/de/chemical/42853

Molekülstruktur von 2-nitromethylenetetrahydro-2H-1,3-thiazine

Identifikatoren & physikalische Daten

CAS No.	58842-20-9
Summenformel	C5H8N2O2S
Durchschnittliche Molmasse	160,2 g/mol
Monoisotopische Masse	160,0306485 g/mol
SMILES	O=[N+]([O-])C=C1NCCCS1
InChIKey	LZTIMERBDGGAJD-UHFFFAOYSA-N
PubChem CID	42853
ChEMBL	CHEMBL3138618
DTXSID	DTXSID7034256

Chemische & physikalische Eigenschaften

XLogP	1,2
Polarare Oberfläche (TPSA)	83,2
H-Brücken-Donoren	1
H-Brücken-Akzeptoren	4
Frei drehbare Bindungen	0
Schwere Atome	10
Formalladung	0
Komplexität	164
Siedepunkt	287.9±40.0 °C(Predicted)
Dichte	1.387±0.06 g/cm3(Predicted)
Löslichkeit	Chloroform (Slightly), Methanol (Slightly)
Aggregatzustand	Solid
pKa (Säurekonstante)	1.16±0.20(Predicted)
Farbe	Off-White to Light Yellow
Stabilität	Light Sensitive
EPA chemische Informationen	Nithiazine (58842-20-9)

Sicherheit & Vorschriften

UN-Transportnummer	2588
Gefahrenklasse	6.1(b)
Verpackungsgruppe	III

Anwendungen & Verwendung

Beschreibung

Nithiazine and other members of the nitromethylene family were shown at an early stage in their development to be cholinergic agonists (and antagonists) by electrophysiology (6). However, unlike nicotine, they mostly act as partial agonists and are open channel blockers, a property resulting from their partial positive charge.

Verwenden

Nithiazine is used as an active ingredient in fly strips (e.g., QuickStrikes Fly Abatement Strip, Sandoz 9023 fly bait station). The strips are most effective against houseflies (Musca domestica). They can be placed in or around the house, animal housing, recycling facilities, or other facilities where abundant houseflies are a nuisance; however, the manufacturer currently does not support residential uses.