1,3-Propanedisulfonic acid

HCID 428573CAS 21668-77-9

Grundinformationen

Standard-SMILES
O=S(=O)(O)CCCS(=O)(=O)O
InChIKey
MGNVWUDMMXZUDI-UHFFFAOYSA-N
Summenformel
C3H8O6S2
Durchschnittliche Molmasse
204,2 g/mol
Monoisotopische Masse
203,97623032

Namen und Bezeichner

Bevorzugter Name
1,3-Propanedisulfonic acid
IUPAC
propane-1,3-disulfonic acid
Englischer Name
Eprodisate
Summenformel
C3H8O6S2
Molmasse
204.22

Namen und Synonyme

Eprodisate21668-77-91,3-Propanedisulfonic acidPropane-1,3-disulfonateEprodisatoPropane-1,3-disulphonate6QFP76V7S7eprodisatumRefChem:590996propane-1,3-disulfonic acid1,3-Propanedisulfonic Acid (50-60% in Water)Eprodisate [INN]
Weitere Namen anzeigen
(50-60% in Water)propane-1,3-disulfonicaciDISODIUM 1,3-PROPANEDISULFONATE1,3-Propanedisulfonic Acid DISODIUM 1,3-PROPANEDISULPHONATEDISODIUM PROPANE-1,3-DISULFONATE1,3-PROPANEDISULFONIC ACID DISODIUM SALT
MFCD00191482starbld000931250-60% in Water1,3-propanesulfonic acid1,3-propanedisulphonic acidEPRODISATE [WHO-DD]UNII-6QFP76V7S7SCHEMBL34216

Datenbank-Bezeichner

CAS
21668-77-9
PubChem CID
428573
DTXSID
DTXSID4048301
ChEMBL
CHEMBL2111092
UNII
6QFP76V7S7
EC Number
679-154-1
Nikkaji
J534.155H

Eigenschaften

Berechnete Struktureigenschaften

XLogP
-1,6
Polarare Oberfläche (TPSA)
126 Ų
H-Brücken-Donoren
2
H-Brücken-Akzeptoren
6
Frei drehbare Bindungen
4
Schwere Atome
11

Physikochemische Eigenschaften

Schmelzpunkt
120 · 120-124 ºC
Siedepunkt
157 °C · 157 °C(Press: 1.4 Torr)
Dichte
1.33 · 1.33
Brechungsindex
1.422 · 1.4220
storage temp.
-20 °C · Store at -20°C
Löslichkeit
125 mg/mL · DMSO: ≥ 125 mg/mL (612.09 mM)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 5 Einträge

Danger

H302 (88.4%): Harmful if swallowed [Warning Acute toxicity, oral];H312 (88.4%): Harmful in contact with skin [Warning Acute toxicity, dermal];H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation];H332 (88.4%): Harmful if inhaled [Warning Acute toxicity, inhalation]

P260, P261, P264, P270, P271, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P362+P364, P363, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 43 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Hazard Classes and CategoriesAcute Tox. 4 (88.4%);Acute Tox. 4 (88.4%);Skin Corr. 1B (100%);Acute Tox. 4 (88.4%)

Sicherheitsdaten

wgk
3
ridadr
3265
hs_code
2904.10.5000
risk_code
36/37/38-34-20/21/22
hazard_code
Xi,C
safety_code
26-36-45-36/37/39-27

Chemie und Industrie

Pharmakologische Informationen

Mechanism of Action · 1 Eintrag

Decline in renal function associated with Amyloid A (AA) amyloidosis can be slowed by eprodisate (Kiacta), a drug that inhibits the deposit of the complex protein in tissues. AA amyloidosis is a serious, frequently fatal disorder involving deposits of amyloid fibrils in various organs and tissues. It is a complication of many chronic inflammatory disorders, but little is known about its etiology or natural history. Eprodisate delays the progression of AA amyloidosis-associated renal disease.

Anwendungen

VerwendenTreatment of secondary (AA) amyloidosis.

Anbieter43 Anbieter

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
宁波君龙新材料有限公司0574 88552216 19032109277 · [email protected]
Hebei Chuanghai Biotechnology Co., Ltd+86-17732866630 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]

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