StartseiteMCPWorkbenchSkills
StartseiteWorkbenchBenachrichtigungenMein Bereich
Huagongshe Open Project:[email protected]KI-Anbindung: llms.txt · MCP-AnleitungDatenschutz · Nutzungsbedingungen · Supportv1.7.8
  1. Startseite
  2. /Verbindung

Natrium-N-chlorbenzolsulfonamid

Chloramine B

HCID 4347343
NotizenReaktionen

Daten werden ergänzt – lade die Seite später neu, um den aktuellen Stand zu sehen

GrundinformationenÜberblickNamen und BezeichnerEigenschaftenSicherheit und RegulatorischesChemie und IndustrieZugehörige ReaktionenNotizen zur Verbindung
TeilstruktursucheÄhnliche Strukturen suchen

Grundinformationen

CAS
127-52-6
Standard-SMILES
O=S(=O)([N-]Cl)c1ccccc1.[Na+]
InChIKey
KDNCILYKSYKEFJ-UHFFFAOYSA-N
Summenformel
C6H5ClNNaO2S
Durchschnittliche Molmasse
213,62 g/mol
Monoisotopische Masse
212,96272136

Überblick

RN given refers to parent cpd

Namen und Bezeichner

Bevorzugter Name
Chloramine B
IUPAC
sodium benzenesulfonyl(chloro)azanide
Lokaler Name
Natrium-N-chlorbenzolsulfonamid
Englischer Name
Chloramine B
Summenformel
C6H5ClNNaO2S
Molmasse
213.62

Namen und Synonyme

CHLORAMINE B127-52-6Chloramine-BNeomagnolBenzene chloramineAnnogenKhloramin BMonochloramine BN-Chlorobenzenesulfonamide sodium saltChloramin BSodium benzenesulfochloramineSodium benzosulfochloramide
Weitere Namen anzeigen
chloraminbchlorogenChlordetalmonochloraminebChloraMine B benzenechloramineChloramine B (Tolamine)
N-Chloro-N-sodiobenzenesulfonamideBenzenesulfochloramide sodiumSodium benzenesulfonchloramideSodium benzenesulfonchloramine(N-Chlorobenzenesulfonamido)-sodiumSodium, (chloro(phenylsulfonyl)amino)-17X76DR1ZMBenzenesulfonamide, N-chloro-, sodium salt

Datenbank-Bezeichner

CAS
127-52-6、304655-80-9
PubChem CID
4347343
DTXSID
DTXSID6041763
UNII
17X76DR1ZM
EC Number
204-847-9、608-481-4

Eigenschaften

Berechnete StruktureigenschaftenWird ergänzt

Polarare Oberfläche (TPSA)
43,5 Ų
H-Brücken-Donoren
0
H-Brücken-Akzeptoren
3
Frei drehbare Bindungen
1
Schwere Atome
12
Formalladung
0
Komplexität
208

Experimentelle und physikochemische Eigenschaften

Chemical ClassesOther Uses -> Biocides/Disinfectants
OdorFaint chlorine odor
Color/FormWHITE POWDER
SolubilitySOL IN 20 PARTS WATER, MORE SOL IN HOT WATER; IN 25 PARTS ETHANOL, YIELDING TURBID SOLN; VERY SPARINGLY SOL IN ETHER, CHLOROFORM /TRIHYDRATE/
Decomposition'Chloramine B' was found to present the greatest fire hazard, decomposing explosively at 185 degree C.
Melting Point170-173 °C
Physical DescriptionWhite solid with a mild odor of chlorine; [Hawley] Slightly beige solid; [MSDSonline]
Other Experimental Properties · 2 Einträge

FAINT CHLORINE ODOR /TRIHYDRATE/

Available chlorine content is 29.5%

Physikochemische Eigenschaften

Sicherheit und Regulatorisches

Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.

GHS-Klassifizierung

GHS Classification · 5 Einträge

This chemical does not meet GHS hazard criteria for 2.3% (1 of 44) of reports.

Danger

H302 (95.5%): Harmful if swallowed [Warning Acute toxicity, oral]

P233, P260, P264, P270, P271, P280, P284, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P330, P342+P316, P363, P403, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 44 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Regulatory Information · 2 Einträge

Status: Active Update: 23-09-2013 https://echa.europa.eu/registration-dossier/-/registered-dossier/6726

Sodium N-chlorobenzenesulfonamide: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Fire Potential'Chloramine B' was found to present the greatest fire hazard, decomposing explosively at 185 degree C.
Hazards Summary · 1 Eintrag

Toxic by ingestion (poisoning by hypochlorites and related agents); [HSDB] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; May cause respiratory sensitization after prolonged contact; May induce methemoglobinemia; [MSDSonline] See Chloramine-T.

Hazard Classes and CategoriesAcute Tox. 4 (95.5%)

Sicherheit und Schutzausrüstung

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological Classification · 1 Eintrag

Substances used on inanimate objects that destroy harmful microorganisms or inhibit their activity. Disinfectants are classed as complete, destroying SPORES as well as vegetative forms of microorganisms, or incomplete, destroying only vegetative forms of the organisms. They are distinguished from ANTISEPTICS, which are local anti-infective agents used on humans and other animals. (From Hawley's Condensed Chemical Dictionary, 11th ed)

Verwendung und Herstellung

Uses · 4 Einträge

Used as an antibacterial agent, disinfectant, and veterinary topical antiseptic; [HSDB]

Using Disinfectants or Biocides [Category: Clean]

ANTIBACTERIAL; VET: TOPICAL ANTISEPTIC

Chloramine B used as a disinfectant is inhibitory to Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus.

Methods of ManufacturingPREPD VIA BENZENESULFONAMIDE: CHATTAWAY, J CHEM SOC 87, 145 (1905); CUIBAN ET AL, PHARMAZIE 13, 407 (1958).
General Manufacturing InformationBenzenesulfonamide, N-chloro-, sodium salt (1:1): ACTIVE
Anwendungen · 1 Eintrag

VerwendenChloramine B's a organochlorine disinfectant, and the effective chloric arrive 26-28%, the property is stable, only loss 0.1% effective chloric after airtight kept 1 year . Slightly soluble in water, and Stimulating & corrosive is small, so the efficacy is slower than hypochlorous acid. Chloramine-B is mainly used for disinfecting container of drinking water, all kind of tableware, fruits and vegetables(5ppm), aquaculture water and enamel instruments(1%). It's also can be used for cleaning breast of cattle, milk cup, livestock urinary tract, festering,etc.

Vor- und nachgelagerte Produkte

Zugehörige Reaktionen

2
Reaktionsaufzeichnung erstellen
Reaktionsgleichung von HRID 560082
HRID 560082als Eduktuspto-grants-2011_11
Reaktionsgleichung von HRID 560088
HRID 560088als Eduktuspto-grants-2011_11

Notizen zur Verbindung

Wird geladen…

Auf dieser SeiteGrundinformationenÜberblickNamen und BezeichnerEigenschaftenSicherheit und RegulatorischesChemie und IndustrieZugehörige ReaktionenNotizen zur Verbindung
Nikkaji
J5.396A
Schmelzpunkt
190 °C · 190°C
Siedepunkt
189 ℃[at · 189℃[at 101 325 Pa]
Dichte
1.484 · 1.484[at 20℃]
Dampfdruck
0 Pa · 0Pa at 20℃
storage temp.
2 · Keep in dark place,Inert atmosphere,2-8°C
Löslichkeit
2 O: · H2O: 0.1 g/mL, clear
Aggregatzustand
solid
pka
1.88 · 1.88[at 20 ℃]
Wasserlöslichkeit
0.1 g/mL · 0.1 g/mL
Merck
14 · 14,2074
BRN
3599287 · 3599287
InChI
InChI=1S/C6H5ClNO2S.Na/c7-8-11(9,10)6-4-2-1-3-5-6;/h1-5H;/q-1;+1
InChIKey
KDNCILYKSYKEFJ-UHFFFAOYSA-N
SMILES
C1(=CC=CC=C1)S(=O)(=O)N(Cl)[Na]
LogP
0.14 at · 0.14 at 26℃
EPA chemische Informationen
Chloramine B (127-52-6)
Disposal Methods · 1 Eintrag

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Toxikologische Informationen

Environmental Fate · 2 Einträge

TERRESTRIAL FATE: Based on observed hydrolysis in laboratory water(1), chloramine B will probably also hydrolyze in moist soils; however, no information on rates in soil was found. Based on the approximate water solubility of 1 part in 20 for the trihydrate(2), chloramine B is not expected to sorb to soils and thus may leach extensively.

AQUATIC FATE: Chloramine B will hydrolyze, resulting in the formation of benzenesulfonamide(1) and hypochlorous acid. Information on hydrolysis rates was not found. Sorption to sediments is not expected to be important. No information was found on biodegradation in aquatic systems.

Adverse EffectsMethemoglobinemia - The presence of increased methemoglobin in the blood; the compound is classified as secondary toxic effect
Effluent Concentrations · 1 Eintrag

Chloramine B in hospital effluents was found to be <100 mg/l(1); however, chloramine B concentration and detection limit were not given. Chemical treatment of wastewater from the production of chloramine B and epoxy resins resulted in the precipitation of benzenesulfonamide(2). This suggests that chloramine B was present in the wastewater.

Soil Adsorption/MobilityBased on its approximate water solubility, a Koc value of 11.4 was calculated (eqns. 4-5 (1)). This low Koc value suggests that chloramine B will not sorb to soils and sediments.
Artificial Pollution Sources · 1 Eintrag

Several thousand pounds of chloramine B are produced and/or imported per year(1). It is used as an antibacterial agent(2) and as a topical antiseptic(2). Chloramine B may also be in the effluent from hospitals(3) and in wastewater from chloramine B production(4).

Environmental Biodegradation · 1 Eintrag

Chloramine B used as a disinfectant is inhibitory to Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus(1). However, concentrations of chloramine B below 100 mg/l did not effect the biological processes in trickling filters(2). A concentration of 100 mg/l of chloramine B, however, caused alteration in the trickling filter biofilm as evidenced by increased development of fungi(2). No information was given on removal efficiencies or biodegradation rates.

Environmental BioconcentrationThe relatively high water solubility of chloramine B suggests that it will not bioconcentrate in aquatic organisms.(SRC)
Non-Human Toxicity ExcerptsCHLORAMINE-B (15 MG/KG, IV) INDUCED PULMONARY EDEMA IN RATS, ACCOMPANIED BY DECR ACETYLESTERASE, SUCCINATE DEHYDROGENASE, ACID PROTEASE, ACID PHOSPHATASE & CYTOCHROME OXIDASE & INCR ALKALINE PHOSPHATASE ACTIVITY IN LUNGS.
Environmental Abiotic DegradationWhen placed in water at room temperature, chloramine B was found to hydrolyze to benzenesulfonamide(1) and hypochlorous acid. Information on hydrolysis rates, however, was not found.
Probable Routes of Human ExposureHuman exposure could come from the manufacture and use of chloramine B in topical antiseptics and antibacterial agents.(SRC)
Environmental Fate/Exposure Summary · 1 Eintrag

Several thousand pounds of chloramine B are produced and/or imported per year. Chloramine B is used as an antibacterial agent and as a topical antiseptic. It is not known how much chloramine B is released to the environment. Small amounts are probably released from medical facilities that may use chloramine B as an antiseptic. In soil and water, chloramine B will hydrolyze. However, no information was found on hydrolysis rates. No information was found on biodegradation, photolysis or volatility. (SRC)

Sicherheitsdaten

wgk
3
tsca
TSCA listed
ridadr
UN 3263 8/PG 2
hs_code
29350090
RTECS-Nr.
DA9300000
risk_code
22-31-34-42-2
hazard_code
C
safety_code
7-22-26-36/37/39-45
hazard_class
5.1
packing_group
III
Speicherklasse
8A - Combustible corrosive hazardous materials
Giftige Stoffe Daten
127-52-6(Hazardous Substances Data)
Hazard Classifications
Acute Tox. 4 OralResp. Sens. 1Skin Corr. 1B

Nachgelagerte Produkte

Benzolsulfonamid

Anbieter100 Anbieter

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Shandong chuangyingchemical Co., Ltd.18853181302 · [email protected]
河北创海生物科技有限公司+86-86-13131129325 · [email protected]
Baoji Guokang Healthchem co.,ltd+8615604608665 15604608665 · [email protected]
Hebei Henghe Import and Export Trading Co. LTD+8618032935937 18032916000 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
南京兰亚化工贸易有限公司+86-25-8331-5620 · [email protected]
上海弘顺生物科技有限公司15901914505 · [email protected]
衢州明锋化工有限公司0570-3062502 13819002126;13819008176 · [email protected]
Syntechem Co.,Ltd[email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
安耐吉化学&3A(安徽泽升科技股份有限公司)400-0056266 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
上海钰康生物科技有限公司+86-18930848214 +86-021-56762820 · [email protected]
上海泰坦科技股份有限公司4006009262 13023226327 · [email protected]
合肥天健化工有限公司551-65418679 15856988503;15837135945 · [email protected]
武汉丰泰威远科技有限公司027-87465837 19945049750 · [email protected]
孝感深远化工有限公司15527621225; 15527621225 · [email protected]
Beckmann-Kenko GmbH+49 4241 9308 88 · [email protected]
山东西亚化学有限公司13355009207 13355009207 · [email protected]
玛雅试剂+86 (573) 82222445 (0)18006601000 452520369 · [email protected]
天津希恩思生化科技有限公司400 638 7771 · [email protected]
Xiamen AmoyChem Co., Ltd+86-86-5926051114 · [email protected]
南京化学试剂股份有限公司025-58369808 17895012682 · [email protected]
嘉兴信思得进出口有限公司+86 (573) 8203-0555 · [email protected]
寿光诺盟化工有限公司0536-5399456 13869682027 · [email protected]
斯百全化学(上海)有限公司021-021-021-67601398-809-809-809 15221380277 · [email protected]
武汉普洛夫生物科技有限公司17612776928 · [email protected]
北京环宇世纪化学科技有限公司hysj_bj.com
HBCChem, Inc.+1-510-219-6317 · [email protected]
上海创赛科技有限公司400-6087598 15021221957 · [email protected]
杭州杰恒化工有限公司0571-87396432 · [email protected]
菏泽市金沃泰化工有限公司+86-15157335533 13505737768 · [email protected]
池州凯隆进出口贸易有限公司[email protected]
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司021-61415566 800-8193336 · [email protected]
九鼎化学(上海)科技有限公司4009209199 · [email protected]
Henan Alfa Chemical Co., Ltd+8618339805032 · [email protected]
厦门志信化学有限公司+86-5922680277 +86-13806087780 · [email protected]
上海珈得尔化学技术有限公司13564435016 13564435016 · [email protected]
湖北圣达利化学有限公司027-83629626 18995558541 · [email protected]
陕西缔都医药化工有限公司+86-29-81139210 +86-17392587031 · [email protected]
Shanghai Yunao International Trade Co., Ltd+86-17621705551 · [email protected]
上海源叶生物科技有限公司18916372613 · [email protected]
上海西格生物科技有限公司021-57810052 18930344717 · [email protected]
湖北威德利化学试剂有限公司15871722230 · [email protected]
武汉市承天精细化工有限公司18164098996 · [email protected]
武汉克米克生物医药技术有限公司027-13163388153 13163388153 · [email protected]
河北克拉维尔生物科技有限公司19930503252 · [email protected]