2-Amino-4-chloro-6-nitrophenol

TIMTEC-BB SBB003676 · 2 mino-4-chloro-6-nitrophenol · 2-Amino-4-chloro-6-nitropheno · 2-AMINO-4-CHLORO-6-NITROPHENOL · 6-Nitro-4-chloro-2-amino phenol · 2-Amino-4-Chloro-6-Nitrophenone · 5-Chloro-2-hydroxy-3-nitroaniline · 2-Hydroxy-3-nitro-5-chloroaniline

https://huagongshe.com/de/chemical/4348294

Molekülstruktur von 2-Amino-4-chloro-6-nitrophenol

Identifikatoren & physikalische Daten

CAS No.	6358-08-3
Summenformel	C6H5ClN2O3
Durchschnittliche Molmasse	188,57 g/mol
Monoisotopische Masse	187,9988697 g/mol
SMILES	Nc1cc(Cl)cc([N+](=O)[O-])c1O
InChIKey	MHAFRUMLQZZSIN-UHFFFAOYSA-N
PubChem CID	4348294
EC No.	228-761-6
DTXSID	DTXSID3074868

Chemische & physikalische Eigenschaften

XLogP	1,7
Polarare Oberfläche (TPSA)	92,1
H-Brücken-Donoren	2
H-Brücken-Akzeptoren	4
Frei drehbare Bindungen	0
Schwere Atome	12
Formalladung	0
Komplexität	184
Schmelzpunkt	306 °F (NTP, 1992)158-162 °C (lit.)
Physical Description	2-amino-4-chloro-6-nitrophenol appears as a solid. (NTP, 1992)
Siedepunkt	308.3±42.0 °C(Predicted)
Dichte	1.655±0.06 g/cm3(Predicted)
Löslichkeit	soluble in Acetone
pKa (Säurekonstante)	6.06±0.38(Predicted)
Aggregatzustand	Powder
Farbe	Dark red to brown
InChI	1S/C6H5ClN2O3/c7-3-1-4(8)6(10)5(2-3)9(11)12/h1-2,10H,8H2
InChIKey	MHAFRUMLQZZSIN-UHFFFAOYSA-N
SMILES	Nc1cc(Cl)cc(c1O)[N+]([O-])=O
CAS Datenbank	6358-08-3(CAS DataBase Reference)
EPA chemische Informationen	2-Amino-4-chloro-6-nitrophenol (6358-08-3)

Sicherheit & Vorschriften

GHS-Einstufung	This chemical does not meet GHS hazard criteria for 2.4% (1 of 42) of reports.WarningH315 (95.2%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 42 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Regulatorische Informationen	Status: Active Update: 29-10-2013 https://echa.europa.eu/registration-dossier/-/registered-dossier/10443
Brandgefahren	Flash point data for this chemical are not available. It is probably combustible. (NTP, 1992)
Gesundheitsgefahren	SYMPTOMS: Symptoms of exposure to this compound may include irritation of the skin, eyes and mucous membranes.
Reaktive Gruppe	Nitro, Nitroso, Nitrate, and Nitrite Compounds, Organic
Reactivity Profile	2-AMINO-4-CHLORO-6-NITROPHENOL may react with strong oxidizing agents (NTP, 1992).
Air and Water Reactions	May be sensitive to air and/or light.
Hazard Classes and Categories	Skin Irrit. 2 (95.2%)
Brandbekämpfung	Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
Erste Hilfe	EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.
Freisetung ohne Brand	SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Anwendungen & Verwendung

Verwenden

Intermediate in the preparation of antipsychotics