N-Oleoyl-L-Serine
Grundinformationen
- CAS
107743-37-3- Standard-SMILES
CCCCCCCC/C=C\CCCCCCCC(=O)N[C@@H](CO)C(=O)O- InChIKey
MBDKGXAMSZIDKF-VJIACCKLSA-N- Summenformel
- C21H39NO4
- Durchschnittliche Molmasse
- 369,5 g/mol
- Monoisotopische Masse
- 369,28790873
Überblick
N-oleoyl-L-serine is an L-serine derivative resulting from the formal condensation of the carboxy group of oleic acid with the amino group of L-serine. It has a role as a bone density conservation agent and a mouse metabolite. It is a N-(fatty acyl)-L-alpha-amino acid and a L-serine derivative. It is functionally related to an oleic acid. It is a conjugate acid of a N-oleoyl-L-serinate.
Namen und Bezeichner
- Bevorzugter Name
- N-Oleoyl-L-Serine
- IUPAC
- (2S)-3-hydroxy-2-[[(Z)-octadec-9-enoyl]amino]propanoic acid
- Englischer Name
- N-Oleoyl-L-Serine
- Summenformel
- C21H39NO4
- Molmasse
- 369.53866
Namen und Synonyme
N-Oleoyl-L-Serine107743-37-3SCD7H2827OL-Serine, N-((9Z)-1-oxo-9-octadecenyl)-L-Serine, N-(1-oxo-9-octadecenyl)-, (Z)-N-((9Z)-1-Oxo-9-octadecen-1-yl)-L-serineL-Serine, N-((9Z)-1-oxo-9-octadecen-1-yl)-CHEBI:136614N-((9Z)-octadec-9-enoyl)-L-serineN-[(9Z)-octadec-9-enoyl]-L-serineRefChem:1092046N-Oleoylserine
Weitere Namen anzeigen
MBDKGXAMSZIDKF-VJIACCKLSA-NL-Serine, N-[(9Z)-1-oxo-9-octadecen-1-yl]-
N-Oleoyl L-Serine(2S)-3-hydroxy-2-[[(Z)-octadec-9-enoyl]amino]propanoic acidUNII-SCD7H2827ON-(9Z-octadecenoyl)-L-serineCHEMBL4515758oleoylserineoleoyl serineoleoyl-serine
Datenbank-Bezeichner
- CAS
107743-37-3- PubChem CID
- 44190514
- DTXSID
DTXSID101371576- ChEMBL
CHEMBL4515758- ChEBI
CHEBI:136614
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 6
- Polarare Oberfläche (TPSA)
- 86,6 Ų
- H-Brücken-Donoren
- 3
- H-Brücken-Akzeptoren
- 4
- Frei drehbare Bindungen
- 18
- Schwere Atome
- 26
- Formalladung
- 0
- Komplexität
- 382
Experimentelle und physikochemische Eigenschaften
LipidsFatty Acyls [FA] -> Fatty amides [FA08] -> N-acyl amino acids [FA0805]
Physikochemische Eigenschaften
- Siedepunkt
- 571.9 · 571.9±50.0 °C(Predicted)
- Dichte
- 1.006 · 1.006±0.06 g/cm3(Predicted)
- storage temp.
- -20 °C · Store at -20°C
- Löslichkeit
- 20 mg/ml; · DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS pH 7.2 (1:1): 0.5 mg/ml
- Aggregatzustand
- Liquid
- pka
- 3.28 · 3.28±0.10(Predicted)
- Farbe
- Colorless to light yellow
Sicherheit und Regulatorisches
Sicherheitsdaten
- Alarmwort
- Achtung
- Gefahrenhinweise
- Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H225
Chemie und Industrie
Anwendungen
BeschreibungBone mass and shape is continuously remodeled by the concerted and balanced action of osteoblasts (bone forming cells) and osteoclasts (bone-resorbing cells). The endocannabinoid system plays an essential role in the maintenance of normal bone mass via signaling through the CB2 receptor. N-Oleoyl-L-serine is an endogenous lipid that has been reported to stimulate bone formation and to inhibit bone resorption.
Anbieter11 Anbieter
United Life Science020-82099279 18988941402 · [email protected]
MedBio脉铂医药021-69568360 18916172912 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
南通全益生物科技有限公司0513-66337626 18051384581 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
上海源叶生物科技有限公司13636370518 · [email protected]
成都标样生物科技有限公司028-81700200 13308200041 · [email protected]
上海宏叶生物科技有限公司400-9205774 400-920-5774 · [email protected]
ChemeGen 中国18818260767 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
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