HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
O-(4-Hydroxy-3-iodphenyl)-3-iod-L-tyrosin
3,3'-Diiodo-L-thyronine · 3,3'-L-Diiodothyronine · L-3,3'-Diiodothyronine · Levothyroxine EP Imp J · Levothyroxine Impurity J · Levothyroxine EP Impurity J · 3,5-Diiodo-L-tyrosinedihydrae · 3,3’-Diiodo-L-thyronine (>97%)
Identifikatoren & physikalische Daten
| CAS No. | 4604-41-5 |
|---|---|
| Summenformel | C15H13I2NO4 |
| Durchschnittliche Molmasse | 525,08 g/mol |
| SMILES | [NH3+][C@@H](Cc1ccc(Oc2ccc(O)c(I)c2)c(I)c1)C(=O)[O-] |
| InChIKey | CPCJBZABTUOGNM-LBPRGKRZSA-N |
| PubChem CID | 44237213 |
| ChEBI | CHEBI:176514 |
| Lokaler Name | O-(4-Hydroxy-3-iodphenyl)-3-iod-L-tyrosin |
Chemische & physikalische Eigenschaften
| Schmelzpunkt | 178-180°C |
|---|---|
| Siedepunkt | 520.7±50.0 °C(Predicted) |
| Dichte | 2.095±0.06 g/cm3(Predicted) |
| Lagerbedingungen | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| Löslichkeit | Aqueous Base (Slightly) |
| Aggregatzustand | Solid |
| pKa (Säurekonstante) | 2.17±0.20(Predicted) |
| Farbe | Off-White to Beige |
| Stabilität | Light Sensitive |
| InChI | InChI=1S/C15H13I2NO4/c16-10-7-9(2-3-13(10)19)22-14-4-1-8(5-11(14)17)6-12(18)15(20)21/h1-5,7,12,19H,6,18H2,(H,20,21)/t12-/m0/s1 |
| InChIKey | CPCJBZABTUOGNM-LBPRGKRZSA-N |
| SMILES | C(O)(=O)[C@H](CC1=CC=C(OC2=CC=C(O)C(I)=C2)C(I)=C1)N |
Sicherheit & Vorschriften
| Wassergefährdungsklasse (WGK) | 3 |
|---|---|
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Beschreibung
3,3''-Diiodo-L-thyronine is a metabolite of thyroid hormone that is also known as T2 or 3,3’-T2. It is derived enzymatically from triiodothyronine isoforms T3 and reverse T3. T2 and its analog 3,5-T2 stimulate the activity of cytochrome c oxidase by blocking inhibition by ATP.