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(-)-Bornan-2-on
Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (1S)- · CAMPHORE · (-)-Alcanfor · Camphor Camphor · Levo-(-)-camphor · (1S)-(-)-Camphor 95% · (1S)-1,7,7-TRIMETHYLBICYCLO[2.2.1]HEPTAN-2-ONE · (1S,4S)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one
Identifikatoren & physikalische Daten
| CAS No. | 464-48-2 |
|---|---|
| Summenformel | C10H16O |
| Durchschnittliche Molmasse | 152,23 g/mol |
| Monoisotopische Masse | 152,12011513 g/mol |
| SMILES | CC1(C)[C@H]2CC[C@]1(C)C(=O)C2 |
| InChIKey | DSSYKIVIOFKYAU-OIBJUYFYSA-N |
| PubChem CID | 444294 |
| ChEMBL | CHEMBL2252949 |
| ChEBI | CHEBI:15397 |
| EC No. | 207-354-7 |
| DTXSID | DTXSID8022036 |
| Lokaler Name | (-)-Bornan-2-on |
Chemische & physikalische Eigenschaften
| XLogP | 2,2 |
|---|---|
| Polarare Oberfläche (TPSA) | 17,1 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 1 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 11 |
| Formalladung | 0 |
| Komplexität | 217 |
| Stoffklassen | Biological Agents -> Plant Oils and Extracts |
| Dichte | 0.992 at 77 °F (NTP, 1992) - Less dense than waterwill float0.990 |
| Löslichkeit | 1 g/800 mL at 77 °F (NTP, 1992)DMF: 30 mg/mlDMSO: 20 mg/mlEthanol: 30 mg/mlEthanol:PBS (pH 7.2)(1:2): 0.33 mg/mlSoluble in water. (0.34 g/L) at 20°C |
| Flammpunkt | 150 °F (NTP, 1992)148 °F |
| Siedepunkt | 399 °F at 760 mmHg (sublimes) (NTP, 1992)204 °C(lit.) |
| Schmelzpunkt | 353.5 °F (NTP, 1992)178-180177-179 °C(lit.) |
| Dampfdichte | 5.24 (NTP, 1992) - Heavier than airwill sink (Relative to Air)5.24 (vs air) |
| Dampfdruck | 1 mmHg at 106.7 °F (NTP, 1992)0.18 [mmHg]4 mm Hg ( 70 °C) |
| Physical Description | L-camphor appears as colorless or white crystals. Fragrant and penetrating odor. Slightly bitter and cooling taste. Odor index at 68 °F: 40. Flash point 149 °F. Burns with a bright, smoky flame. Sublimes appreciably at room temperature and pressure14% sublimes within 60 minutes at 176 °F and 12 mmHg. (NTP, 1992)Colorless to white solid with a strong fragrant odor[CAMEO] White powder[Sigma-Aldrich MSDS] |
| Selbstentzündungstemperatur | 871 °F (NTP, 1992) |
| Brechungsindex | -44 ° (C=20, EtOH) |
| Lagerbedingungen | Sealed in dry,Room Temperature |
| Aggregatzustand | Adhering Crystals or Crystalline Powder |
| Farbe | White to yellow |
| Wichte | 0.9853 (18℃) |
| Geruch | at 10.00 % in dipropylene glycol. camphor |
| Geruchsart | camphoreous |
| Explosionsgrenze | 0.6-4.5%(V) |
| Merck | 14,1732 |
| BRN | 4291747 |
| Stabilität | Stable. Incompatible with strong reducing agents, strong oxidizing agents, chlorinated solvents. Protect from direct sunlight. |
| InChI | 1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3/t7-,10+/m0/s1 |
| InChIKey | DSSYKIVIOFKYAU-OIBJUYFYSA-N |
| SMILES | [H][C@]12CC[C@](C)(C(=O)C1)C2(C)C |
| LogP (Verteilungskoeffizient) | 2.089 (est) |
| CAS Datenbank | 464-48-2(CAS DataBase Reference) |
| EPA chemische Informationen | l-Camphor (464-48-2) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH228 (35.5%): Flammable solid [Danger Flammable solids]P203, P210, P240, P241, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 138 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | Chemical: Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (1S)-(1S)-(-)-Camphor: Does not have an individual approval but may be used under an appropriate group standard |
| Weitere Sicherheitsinformationen | IMAP assessments - Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (1S)-: Environment tier I assessment |
| DOT-Kennzeichnung | Flammable Solid |
| Brandgefahren | This chemical is flammable. (NTP, 1992) |
| Gesundheitsgefahren | SYMPTOMS: Ingestion of this compound may cause nausea, vomiting, vertigo, mental confusion, delirium, convulsions, coma, respiratory failure or death. It may also cause a burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, severe irritation and possible destruction to the tissues of the mucous membranes, upper respiratory tract, eyes and skin. Other symptoms may include congestion and edematous changes in the gastrointestinal tract, kidneys and brain. Ingestion may result in burning in the mouth and throat, epigastric pain, thirst, feeling of tension, dizziness, irrational behavior, unconsciousness, rigidity, rapid pulse, slow respiration, twitching of the facial muscles and muscular spasms. Other symptoms may include flickering, darkening or veiling of vision, noises in the ears and weakness. Exposure to this compound may also result in a feeling of warmth, depression of the central nervous system, difficult breathing, a characteristic breath odor and anuria. Colic may also be a symptom of exposure. Other symptoms may include eye irritation, sore throat, excitement, fever, bluish lips, pale face, loss of sense of smell and agitation. |
| Gefahrenübersicht | May cause severe skin, eye, mucous membrane, and upper respiratory tract irritationMay cause CNS depression and other nervous system effects |
Anwendungen & Verwendung
Verwenden
(1S)-(-)-Camphor is used as chiral intermediate and chiral auxiliary precursor. It is used in the synthesis of high-potency sweeteners. It acts as catalytic agent and petrochemical additive.