Chitin

O-2-(Acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)-2-(acetylamino)-2-deoxy-beta-D-glucopyranose

HCID 444514

Grundinformationen

CAS
13319-32-9
Standard-SMILES
CC(=O)N[C@@H]1[C@@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3NC(C)=O)[C@H](O)[C@H]2NC(C)=O)[C@@H](CO)O[C@H]1O
InChIKey
WZZVUHWLNMNWLW-VFCSDQTKSA-N
Summenformel
C24H41N3O16
Durchschnittliche Molmasse
627,6 g/mol
Monoisotopische Masse
627,24868223

Überblick

Beta-D-GlcpNAc-(1->4)-beta-D-GlcpNAc-(1->4)-beta-D-GlcpNAc is a linear amino trisaccharide consisting of three N-acetyl-beta-D-glucosamine residues linked (14). It has a role as an epitope.

Namen und Bezeichner

Bevorzugter Name
O-2-(Acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)-2-(acetylamino)-2-deoxy-beta-D-glucopyranose
IUPAC
N-[(2R,3R,4R,5S,6R)-5-[(2S,3R,4R,5S,6R)-3-acetamido-5-[(2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,4-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide
Lokaler Name
Chitin
Englischer Name
Chitin
Summenformel
C6H11NO4X2
Molmasse
161.16

Namen und Synonyme

13319-32-9DTXSID801100881GlyTouCan:G47362BJRefChem:1048464DTXCID201532583G47362BJO-2-(Acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)-2-(acetylamino)-2-deoxy-beta-D-glucopyranoseTRIACETYLCHITOTRIOSEbeta-N,N',N''-triacetylchitotrioseN,N',N''-triacetyl chitotriose beta-anomerCHEBI:71404beta-D-GlcpNAc-(1->4)-beta-D-GlcpNAc-(1->4)-beta-D-GlcpNAc
Weitere Namen anzeigen
DEACETYLATED CHITINa-chitinChitin-13CXChitin (powder)SQUID PEN CHITINColloidal ChitinCHITINMICROPARTICLESPOLY-N-ACETYLGLUCOSAMINECHITIN FROM SHRIMP SHELLSBETA-(1,4)-2-ACETAMIDO-2-DEOXY-D-GLUCOSE
GlcNAcbeta1-4GlcNAcbeta1-4GlcNAcbeta(beta)-N,N',N''-triacetyl chitotriosebeta-D-GlcNAc-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1->4)-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1->4)-2-acetamido-2-deoxy-beta-D-glucopyranoseN-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosamine1at51at62r0h

Datenbank-Bezeichner

CAS
13319-32-9、1398-61-4
PubChem CID
444514
DTXSID
DTXSID801100881
ChEMBL
CHEMBL1222017
ChEBI
CHEBI:71404
UNII
ALA7M3MVL3
Nikkaji
J419.926J

Eigenschaften

Berechnete Struktureigenschaften

XLogP
-6,9
Polarare Oberfläche (TPSA)
295 Ų
H-Brücken-Donoren
11
H-Brücken-Akzeptoren
16
Frei drehbare Bindungen
10
Schwere Atome
43

Experimentelle und physikochemische Eigenschaften

DrugsPharmaceuticals -> Listed in ZINC15
Physical DescriptionSolid

Physikochemische Eigenschaften

Schmelzpunkt
300 °C · >300°C (dec.)
Siedepunkt
737.18 °C · 737.18°C (rough estimate)
Dichte
1.3744 · 1.3744 (rough estimate)
Brechungsindex
1.6 · 1.6000 (estimate)
storage temp.
Room Temp
Löslichkeit
dilute aqueous acid (pH <6.5).: soluble

Sicherheit und Regulatorisches

Sicherheitsdaten

F
3
wgk
3
tsca
TSCA listed
hs_code
32139000
RTECS-Nr.
FM6300000
risk_code
20/21/22-36/37/38

Chemie und Industrie

Pharmakologische Informationen

Tissue LocationsFibroblasts
Cellular LocationsExtracellular
Metabolite Pathways2-Hydroxyglutric Aciduria (D And L Form)
Anwendungen · 2 Einträge

BeschreibungChitin is the most abundant natural amino polysaccharide. It has a similar annual yield as cellulose. Chitin is a kind of highly valuable material in biomedical applications because of its high biocompatibility, biodegradability and non-toxicity as well as its antimicrobial activity and low immunogenicity. It can be easily processed into gels, membrane, nanofibers, beads, nanoparticle, scaffold and sponges, enables its wide applications. In the tissue engineering, it can be used for manufacturing polymer scaffold to satisfy the demands of repairing, replacing, maintaining, or enhancing the function of a particular tissue or organ. In wound dressing, chitin can be used as antimicrobial reagent. In the field of drug delivery, the water-soluble carboxymethyl chitin (CMC) nanoparticle can be used as an effective carrier in drug delivery.

Verwendenchitin (chitine) is a moisture retainer and film-forming agent. This is a naturally occurring polysaccharide found in the shells of crustaceans, such as shrimp and crab, as well as in some fungi and algae. It is also a naturally occuring fibre found in the shells of shellfish. Used for the analysis of chitinase. lysozyme substrate.

Anbieter100 Anbieter

北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
上海如吉生物科技发展有限公司+86-21-65211385-8001 36031160 · [email protected]
陕西瑞林帕尼尔生物科技有限公司029-86107037-8019 15332321378 · [email protected]
Ergänzende Hinweise · 1 Eintrag

DefinitionChEBI: Chitin is a polysaccharide comprisingchains of N-acetyl-d-glucosamine,a derivative of glucose. Chitin isstructurally very similar to celluloseand serves to strengthen the supportingstructures of various invertebrates. It is the second most abundant biopolymer on earth, found especially in insects and fungi.

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