Dicycloplatin
Grundinformationen
- CAS
287402-09-9- Standard-SMILES
N.N.O=C(O)C1(C(=O)O)CCC1.O=C([O-])C1(C(=O)[O-])CCC1.[Pt+2]- InChIKey
IIJQICKYWPGJDT-UHFFFAOYSA-L- Summenformel
- C12H20N2O8Pt
- Durchschnittliche Molmasse
- 515,38 g/mol
- Monoisotopische Masse
- 515,08676
Überblick
Dicycloplatin is a third-generation, supramolecular platinum-based compound composed of carboplatin linked, by a strong hydrogen bond, to 1,1-cyclobutane dicarboxylate (CBDCA), with potential antineoplastic activity. Although the exact mechanism of action has yet to be fully elucidated, dicycloplatin appears to have a mechanism of action similar to that of other platinum-based compounds, which involves both DNA binding and the formation of DNA crosslinks. This mechanism results in the induction of apoptosis and cell growth inhibition. Compared to carboplatin alone, dicycloplatin shows enhanced solubility and stability in aqueous solution and appears to have a more favorable toxicity profile.
Namen und Bezeichner
- Bevorzugter Name
- Dicycloplatin
- IUPAC
- azane;cyclobutane-1,1-dicarboxylate;cyclobutane-1,1-dicarboxylic acid;platinum(2+)
- Englischer Name
- Dicycloplatin (DCP)
- Summenformel
- C12H18N2O8Pt
- Molmasse
- 513.37
Namen und Synonyme
Dicycloplatin287402-09-9Dicycloplatin (DCP)0KC57I4UNBAzane, 1-carboxycyclobutane-1-carboxylate, platinum(2+)Platinum(2+) 1-carboxycyclobutanecarboxylate ammoniate (1:2:2)azane;cyclobutane-1,1-dicarboxylate;cyclobutane-1,1-dicarboxylic acid;platinum(2+)UNII-0KC57I4UNBDICYCLOPLATIN [WHO-DD]SCHEMBL29369835Platinum, diammine(1,1-cyclobutanedi(carboxylato-kappaO)(2-))-, (sp-4-2)-, 1,1-cyclobutanedicarboxylate (1:1)Platinum, diammine(1,1-cyclobutanedicarboxylato(2-)-kappaO,kappaO'')-, (sp-4-2)-, 1,1-cyclobutanedicarboxylate (1:1)
Weitere Namen anzeigen
Dicydoplatin
DB-119035Cis-diammine(1,1-cyclobutanedicarboxylate)platinum(II)Q19776556PLATINUM, DIAMMINE(1,1-CYCLOBUTANEDI(CARBOXYLATO-.KAPPA.O)(2-))-, (SP-4-2)-, 1,1-CYCLOBUTANEDICARBOXYLATE (1:1)PLATINUM, DIAMMINE(1,1-CYCLOBUTANEDICARBOXYLATO(2-)-.KAPPA.O,.KAPPA.O'')-, (SP-4-2)-, 1,1-CYCLOBUTANEDICARBOXYLATE (1:1)
Datenbank-Bezeichner
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 157 Ų
- H-Brücken-Donoren
- 4
- H-Brücken-Akzeptoren
- 10
- Frei drehbare Bindungen
- 2
- Schwere Atome
- 23
- Formalladung
- 0
- Komplexität
- 317
Chemie und Industrie
Anbieter33 Anbieter
陕西缔都新材料有限公司81124267 17392282731 · [email protected]
Shaanxi LonierHerb Bio Technology Co Ltd+86-86-+86-86-029-87551862 15002946897 · [email protected]
湖北海克斯生化有限公司17362916295; 17362916295 · [email protected]
江苏豪隆化工有限公司0513-89083520 13328092525 · [email protected]
河北枫嘉新材料科技有限公司+86-0311-87836622 +86-18712993135 · [email protected]
湖北威德利化学试剂有限公司17771473825 13385289472 · [email protected]
Zhejiang J&C Biological Technology Co.,Limited+1-2135480471 · [email protected]
武汉贝尔卡药业有限公司15377519203 · [email protected]
湖北威德利化学试剂有限公司186-02735115 18602735115 · [email protected]
上海丽康新材料有限公司+86-16631818819 +86-17736933208 · [email protected]
武汉贝乐叶生物医药科技有限公司18086118078 · [email protected]
湖北源梦生物科技有限公司027-68897569 18120462897 · [email protected]
南京伶亚生物医药科技有限公司18068075658 · [email protected]
常州安奈凯医药科技有限公司
Zugehörige Reaktionen
0
Keine Reaktionsaufzeichnungen unter den aktuellen Filterkriterien.
Notizen zur Verbindung
Wird geladen…