HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Lodoxamide Impurity 20
AloMide · AlMide · U-42585-E · LodoxaMide troMetaMol · Lodoxamidetromethamine · Lodoxamide Tromethamide · LodoxaMide troMethaMineon · Lodossammonium butanetriol
Identifikatoren & physikalische Daten
| CAS No. | 63610-09-3 |
|---|---|
| Summenformel | C15H17ClN4O9 |
| Durchschnittliche Molmasse | 432,77 g/mol |
| Monoisotopische Masse | 432,0684058 g/mol |
| SMILES | N#Cc1cc(NC(=O)C(=O)O)c(Cl)c(NC(=O)C(=O)O)c1.NC(CO)(CO)CO |
| InChIKey | KUGJPYZIWCRREB-UHFFFAOYSA-N |
| PubChem CID | 44563 |
| ChEMBL | CHEMBL1201175 |
| DTXSID | DTXSID20979825 |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 243 |
|---|---|
| H-Brücken-Donoren | 8 |
| H-Brücken-Akzeptoren | 11 |
| Frei drehbare Bindungen | 7 |
| Schwere Atome | 29 |
| Formalladung | 0 |
| Komplexität | 543 |
| Lagerbedingungen | under inert gas (nitrogen or Argon) at 2–8 °C |
| Löslichkeit | DMSO: 20 mg/mL (36.11 mM and warming) |
| Aggregatzustand | Solid |
| Farbe | White to light yellow |
Sicherheit & Vorschriften
| Alarmwort | Warnung |
|---|---|
| Gefahrenhinweise | Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H302 |
Anwendungen & Verwendung
Beschreibung
Lodoxamide tromethamine was launched as an ophthalmic formulation for the treatment of allergic conjunctivitis. It appears to act as a mast cell stabilizer inhibiting degranulation and the release of histamine and other vasoactive products in a similar manner to sodium cromoglycate. The compound is also under investigation as an orally active antiallergic/antiasthmatic agent.
Verwenden
cataract treatment