psi,psi-Carotin
Lycopen · Lycopene oil · JARCOPENE(TM) · Lycopene Powder · LYCOSOURCE · Lycoypene · E 160d · LYCOVIT
Identifikatoren & physikalische Daten
| CAS No. | 502-65-8 |
|---|---|
| Summenformel | C40H56 |
| Durchschnittliche Molmasse | 536,9 g/mol |
| Monoisotopische Masse | 536,43820179 g/mol |
| SMILES | CC(C)=CCC/C(C)=C/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C=C(\C)CCC=C(C)C |
| InChIKey | OAIJSZIZWZSQBC-GYZMGTAESA-N |
| PubChem CID | 446925 |
| ChEMBL | CHEMBL501174 |
| ChEBI | CHEBI:15948 |
| EC No. | 207-949-1 |
| DTXSID | DTXSID2046593 |
| Lokaler Name | psi,psi-Carotin |
Chemische & physikalische Eigenschaften
| XLogP | 15,6 |
|---|---|
| Polarare Oberfläche (TPSA) | 0 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 0 |
| Frei drehbare Bindungen | 16 |
| Schwere Atome | 40 |
| Formalladung | 0 |
| Komplexität | 1.050 |
| Arzneimittel | Pharmaceuticals -> Listed in ZINC15 |
| Lipide | Lipids -> Prenol Lipids [PR] -> Isoprenoids [PR01] -> C40 isoprenoids (tetraterpenes) [PR0107] |
| Kosmetika | Cosmetic colorant |
| Lebensmittelzusatzstoffe | Foods -> FDA Regulatory Status of Color AdditivesFLAVORING AGENT OR ADJUVANT -> FDA Substance added to food |
| Dietary Ingredients | Lycopene |
| Schmelzpunkt | 175 °C172-173°C |
| Physical Description | Solid |
| Siedepunkt | 644.94°C (rough estimate) |
| Dichte | 0.9380 (estimate) |
| Brechungsindex | 1.5630 (estimate) |
| FEMA | 4110 | TOMATO LYCOPENE |
| Lagerbedingungen | -70°C |
| Löslichkeit | Benzene (Slightly), Chloroform (Sparingly), Ethyl Acetate (Very Slightly), Methane |
| Aggregatzustand | powder |
| Farbe | Red to Very Dark Red |
| Geruch | balsam oriental |
| Geruchsart | balsamic |
| Biologische Quelle | tomato |
| Stabilität | Heat sensitive - store at -70 C. Combustible. Incompatible with strong oxidizing agents. |
| Hauptanwendungen | cleaning productscosmeticsfood and beveragespersonal care |
| Kosmetik-Inhaltsstoffe Funktionen | ANTIOXIDANTCOLORANT |
| InChIKey | OAIJSZIZWZSQBC-BOJOQWLHSA-N |
| SMILES | C\C(C)=C\CC\C(C)=C\C=C\C(C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(C)\C=C\C=C(/C)CC\C=C(\C)C |
| LogP (Verteilungskoeffizient) | 15.19 |
| CAS Datenbank | 502-65-8(CAS DataBase Reference) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 100% (203 of 203) of all reports.Not ClassifiedAggregated GHS information provided per 203 reports by companies from 1 notifications to the ECHA C&L Inventory. |
|---|---|
| Regulatorische Informationen | Regulation (EC) No 178/2002 (amended).psi.,.psi.-Carotene: Does not have an individual approval but may be used under an appropriate group standard |
| Hazard Classes and Categories | Not Classified |
| Minimum Risk Level | A large body of human and animal research suggests that oral forms of lutein and lycopene may provide benefits for eye, prostate, skin and cardiovascular health. The increased awareness and use of lutein and lycopene in dietary supplements warrants a comprehensive review of their safety. The Highest Observed Intake (HOI) risk assessment method indicates that the evidence of safety is strong at intakes up to 20mg/d for lutein and 75 mg/d for lycopene, and these levels are identified as the respective Observed Safe Level (OSL). Much higher levels have been tested without adverse effects and may be safehowever, the data are not sufficient for a confident conclusion of long-term safety. |
| Skin Symptoms | Lycopenemia, characterized by pigmentation of the skin color from yellow to orange, is caused by the excess consumption of lycopene resources taken through the diet. Lycopene deposits take place in the stratum corneum. The symptoms are eliminated with changes in the diet. |
| Toxizitätsübersicht | Lycopene is one of the most potent antioxidants, and is found in fruits and vegetables. High-intake of lycopene has decreased the risks of natural toxins, including mycotoxins and bacterial toxins, and chemical toxins, including heavy metals, pesticides and herbicides.Lycopene is a natural carotenoid found predominantly in tomatoes and tomato-based products. The safety of synthetic lycopene as beadlet formulations includes acute and subchronic safety studies, reproductive studies, genotoxicity studies, metabolic studies, and exploratory studies on the hepatic uptake of lycopene. It has a low order of acute toxicity and no significant toxicity has been observed in rats treated with lycopene in the diet at doses of up to 500 mg/kg bw/day for 14 weeks, or 1000 mg/kg bw/day for 4 weeks. No teratogenic effects were noted in a rat two-generation study (1000 ppm in the diet) or in a teratology study in rats with 1000 mg/kg bw/day lycopene as beadlet formulations. Unformulated pure crystalline lycopene and lycopene as a 10% beadlet formulation were not genotoxic in a comprehensive battery of tests |
Anwendungen & Verwendung
Beschreibung
Lycopene is a red-colored carotenoid found in tomatoes and other red fruits and vegetables. Carotenoids, including lycopene, are powerful antioxidants that efficiently quench singlet oxygen. Presumably through this action, carotenoids may protect against cancers, cardiovascular stress, and other diseases.
Occurrence
Lycopene is a carotenoid that occurs naturally in tomatoes.
Verwenden
Lycopene extract from tomato is intended for use as a food colour. It provides the similar colour shades, ranging from yellow to red, as do the natural and synthetic lycopenes. Lycopene extract from tomato is also used as a food/dietary supplement in products where the presence of lycopene provides a specific value (e.g., antioxidant or other claimed health benefits). The product may also be used as an antioxidant in food supplements. Lycopene extract from tomato is intended for use in the following food categories: baked goods, breakfast cereals, dairy products including frozen dairy desserts, dairy product analogues, spreads, bottled water, carbonated beverages, fruit and vegetable juices, soybean beverages, candy, soups, salad dressings, and other foods and beverages.