HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
CMP-Neu5Ac
CMP-Neu5Ac · CMP-Sialic acid · cmp-nan · CMP-Sia · CMP-NANA · CMP-NeuAc · CMP acetylneuraminic acid · CYTIDINE 5'-MONOPHOSPHO-N-
Identifikatoren & physikalische Daten
| CAS No. | 3063-71-6 |
|---|---|
| Summenformel | C20H31N4O16P |
| Durchschnittliche Molmasse | 614,5 g/mol |
| Monoisotopische Masse | 614,14726791 g/mol |
| SMILES | CC(=O)N[C@H]1[C@H]([C@H](O)[C@H](O)CO)O[C@](OP(=O)(O)OC[C@H]2O[C@@H](n3ccc(N)nc3=O)[C@H](O)[C@@H]2O)(C(=O)O)C[C@@H]1O |
| InChIKey | TXCIAUNLDRJGJZ-BILDWYJOSA-N |
| PubChem CID | 448209 |
| ChEMBL | CHEMBL1234647 |
| ChEBI | CHEBI:16556 |
Chemische & physikalische Eigenschaften
| XLogP | -6,7 |
|---|---|
| Polarare Oberfläche (TPSA) | 321 |
| H-Brücken-Donoren | 10 |
| H-Brücken-Akzeptoren | 16 |
| Frei drehbare Bindungen | 11 |
| Schwere Atome | 41 |
| Formalladung | 0 |
| Komplexität | 1.120 |
| Physical Description | Solid |
| Collision Cross Section | 215.5 Ų [M-H]- [CCS Type: DTMethod: single field calibrated with Agilent tune mix (Agilent)]220.7 Ų [M+Na]+ [CCS Type: DT |
| Dichte | 2.02±0.1 g/cm3(Predicted) |
| Lagerbedingungen | -20°C |
| pKa (Säurekonstante) | 1.30±0.50(Predicted) |
| Aggregatzustand | solid |
| Farbe | white |
| Löslichkeit | water: 20mg/mL |
| BRN | 4224251 |
| InChIKey | VFRHSOGUONIUOR-SQQGBWPWNA-M |
| SMILES | [P](=O)(OC3(OC(C(C(C3)O)NC(=O)C)C(O)C(O)CO)C(=O)O)(OCC1OC(C(C1O)O)N2C=CC(=NC2=O)N)O |
Sicherheit & Vorschriften
| F | 10-21 |
|---|---|
| Wassergefährdungsklasse (WGK) | 3 |
| R-Sätze (R) | 36/37/38 |
| Sicherheitshinweise (S) | 26 |
| Lagerklasse | 13 - Non Combustible Solids |
Anwendungen & Verwendung
Verwenden
Cytidine-5′-monophospho-N-acetylneuraminic acid sodium salt has been used: as a standard in high-performance anion-exchange chromatography with pulsed amperometric detection (HPAEC-PAD) for nucleotide sugar analysis in Joubert syndrome type 10 (JBTS10) patient cells and control skin fibroblasts, As a substrate for the enzymatic sialylation of G2 glycoforms, resialylation assay, in in-vitro sialyltransferase assay