N-Acetyl-L-methionin

N-acetyl-L-methionine

HCID 448580CAS 65-82-7

Grundinformationen

Standard-SMILES
CSCC[C@H](NC(C)=O)C(=O)O
InChIKey
XUYPXLNMDZIRQH-LURJTMIESA-N
Summenformel
C7H13NO3S
Durchschnittliche Molmasse
191,25 g/mol
Monoisotopische Masse
191,06161445

Namen und Bezeichner

Bevorzugter Name
N-acetyl-L-methionine
IUPAC
(2S)-2-acetamido-4-methylsulfanylbutanoic acid
Lokaler Name
N-Acetyl-L-methionin
Englischer Name
N-Acetyl-L-methionine
Summenformel
C7H13NO3S
Molmasse
191.25

Namen und Synonyme

N-Acetyl-L-methionine65-82-7N-AcetylmethionineAcetyl-L-methionineMethionamineThiomedonAcetylmethionineL-(N-Acetyl)methionineL-Methionine, N-acetyl-MethioninAcMetMethionine, N-acetyl-, L-
Weitere Namen anzeigen
NAMAC-MET-OHN-ACETYL-L-METHIONINE:AC-MET-OHn-acetyl-l-methionin01310-25GN-AC-L-MET
N-Ac-MetNalpha-acetyl-L-methionine(2S)-2-acetamido-4-methylsulfanylbutanoic acid(2S)-2-acetamido-4-(methylsulfanyl)butanoic acidFOLLICUSAN9J12WX5B6ACHEBI:21557DTXSID00883214

Datenbank-Bezeichner

CAS
65-82-7
PubChem CID
448580
DTXSID
DTXSID00883214
ChEBI
CHEBI:21557
UNII
9J12WX5B6A
EC Number
200-617-7
Nikkaji
J4.840B

Eigenschaften

Berechnete Struktureigenschaften

XLogP
0,1
Polarare Oberfläche (TPSA)
91,7 Ų
H-Brücken-Donoren
2
H-Brücken-Akzeptoren
4
Frei drehbare Bindungen
5
Schwere Atome
12

Experimentelle und physikochemische Eigenschaften

LogP-0.03
Solubility · 2 Einträge

307000

307mg/mL at 25 °C

Melting Point · 2 Einträge

105.5

105.5 °C

Physical DescriptionSolid
Collision Cross Section · 2 Einträge

150.1 Ų [M+Na]+ [CCS Type: DT; Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)];142.6 Ų [M-H]- [CCS Type: DT; Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]

142.7 Ų [M-H]-;150.2 Ų [M+Na]+

Physikochemische Eigenschaften

Schmelzpunkt
103 · 103-106 °C(lit.)
Siedepunkt
235 °C · 235 °C(Press: 12 Torr)
Dichte
1.2684 · 1.2684 (rough estimate)
Brechungsindex
-21 ° · -21 ° (C=1, H2O)
storage temp.
Sealed in dry,Room Temperature
Löslichkeit
100 mg/mL, · methanol: soluble100mg/mL, clear, colorless

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

This chemical does not meet GHS hazard criteria for 57.1% (4 of 7) of all reports.

Danger

H315 (28.6%): Causes skin irritation [Warning Skin corrosion/irritation];H318 (14.3%): Causes serious eye damage [Danger Serious eye damage/eye irritation];H319 (28.6%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (28.6%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 7 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 4 of 7 reports by companies.;There are 3 notifications provided by 3 of 7 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Regulatory Information · 2 Einträge

Regulation (EC) No 178/2002 (amended)

L-Methionine, N-acetyl-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazard Classes and CategoriesSkin Irrit. 2 (28.6%);Eye Dam. 1 (14.3%);Eye Irrit. 2A (28.6%);STOT SE 3 (28.6%)

Toxikologische Informationen

Toxicity Summary · 2 Einträge

The panel concluded that the 115 amino acid alkyl amides listed below are safe in the present practices of use and concentration in cosmetics, when formulated to be non-irritating...Acetyl Methionine

Safe for use in cosmetics, with qualifications

Regulatorische Informationen

Regulatory Information · 2 Einträge

Regulation (EC) No 178/2002 (amended)

L-Methionine, N-acetyl-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Sicherheitsdaten

wgk
3
tsca
TSCA listed
hs_code
29309070
RTECS-Nr.
PD0480000
risk_code
36/37/38
hazard_code
Xi

Chemie und Industrie

Pharmakologische Informationen

Tissue LocationsPlacenta

Verwendung und Herstellung

UsesCIR ingredient: Acetyl Methionine
Use ClassificationCosmetics -> Skin conditioning
General Manufacturing InformationL-Methionine, N-acetyl-: ACTIVE

Anbieter50 Anbieter

北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Hangzhou Go Top Peptide Biotech0571-88211921 · [email protected]
INTATRADE GmbH+49 3493/605464 · [email protected]

Ergänzende Hinweise

DefinitionChEBI: An L-methionine derivative that is L-methionine in which one of the amine hydrogens is substituted by an acetyl group.

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