N-Acetyl-L-methionin
N-acetyl-L-methionine
Grundinformationen
- CAS
65-82-7- Standard-SMILES
CSCC[C@H](NC(C)=O)C(=O)O- InChIKey
XUYPXLNMDZIRQH-LURJTMIESA-N- Summenformel
- C7H13NO3S
- Durchschnittliche Molmasse
- 191,25 g/mol
- Monoisotopische Masse
- 191,06161445
Überblick
N-acetyl-L-methionine is an L-methionine derivative that is L-methionine in which one of the amine hydrogens is substituted by an acetyl group. It has a role as a nutraceutical. It is a N-acetylmethionine, a N-acetyl-L-amino acid and a L-methionine derivative. It is a conjugate acid of a N-acetyl-L-methionine(1-). It is an enantiomer of a N-acetyl-D-methionine.
Namen und Bezeichner
- Bevorzugter Name
- N-acetyl-L-methionine
- IUPAC
- (2S)-2-acetamido-4-methylsulfanylbutanoic acid
- Lokaler Name
- N-Acetyl-L-methionin
- Englischer Name
- N-Acetyl-L-methionine
- Summenformel
- C7H13NO3S
- Molmasse
- 191.25
Namen und Synonyme
N-Acetyl-L-methionine65-82-7N-AcetylmethionineAcetyl-L-methionineMethionamineThiomedonAcetylmethionineL-(N-Acetyl)methionineL-Methionine, N-acetyl-MethioninAcMetMethionine, N-acetyl-, L-
Weitere Namen anzeigen
NAMAC-MET-OHN-ACETYL-L-METHIONINE:AC-MET-OHn-acetyl-l-methionin01310-25GN-AC-L-MET
N-Ac-MetNalpha-acetyl-L-methionine(2S)-2-acetamido-4-methylsulfanylbutanoic acid(2S)-2-acetamido-4-(methylsulfanyl)butanoic acidFOLLICUSAN9J12WX5B6ACHEBI:21557DTXSID00883214
Datenbank-Bezeichner
- CAS
65-82-7- PubChem CID
- 448580
- DTXSID
DTXSID00883214- ChEBI
CHEBI:21557- UNII
- 9J12WX5B6A
- EC Number
- 200-617-7
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 0,1
- Polarare Oberfläche (TPSA)
- 91,7 Ų
- H-Brücken-Donoren
- 2
- H-Brücken-Akzeptoren
- 4
- Frei drehbare Bindungen
- 5
- Schwere Atome
- 12
- Formalladung
- 0
- Komplexität
- 172
Experimentelle und physikochemische Eigenschaften
DrugsPharmaceuticals -> Listed in ZINC15
Cosmetics
Cosmetic ingredients (Acetyl Methionine) -> CIR (Cosmetic Ingredient Review)
Skin conditioning
LogP-0.03
Food AdditivesNUTRIENT SUPPLEMENT -> FDA Substance added to food
Solubility307mg/mL at 25 °C
Melting Point105.5 °C
Physical DescriptionSolid
Collision Cross Section
142.6 Ų [M-H]- [CCS Type: DT; Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]
142.7 Ų [M-H]-
Physikochemische Eigenschaften
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
This chemical does not meet GHS hazard criteria for 57.1% (4 of 7) of all reports.
Danger
H315 (28.6%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 7 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Regulatory Information
Regulation (EC) No 178/2002 (amended)
L-Methionine, N-acetyl-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazard Classes and CategoriesSkin Irrit. 2 (28.6%)
Toxikologische Informationen
Toxicity Summary
The panel concluded that the 115 amino acid alkyl amides listed below are safe in the present practices of use and concentration in cosmetics, when formulated to be non-irritating...Acetyl Methionine
Safe for use in cosmetics, with qualifications
Sicherheitsdaten
- wgk
- 3
- tsca
- TSCA listed
- hs_code
- 29309070
Chemie und Industrie
Pharmakologische Informationen
Tissue LocationsPlacenta
Verwendung und Herstellung
UsesCIR ingredient: Acetyl Methionine
Use ClassificationCosmetics -> Skin conditioning
General Manufacturing InformationL-Methionine, N-acetyl-: ACTIVE
Vor- und nachgelagerte Produkte
Vorgelagerte Rohstoffe
Ergänzende Hinweise
DefinitionChEBI: An L-methionine derivative that is L-methionine in which one of the amine hydrogens is substituted by an acetyl group.
Zugehörige Reaktionen
15
Notizen zur Verbindung
Wird geladen…