HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Mesopram
SH 636 · mesopram · ZK 117137 · DaxalipraM · (R)-MesopraM · (R)-5-(4-Methoxy-3-propoxyphenyl)-5-methyl-2-oxazolidinone · (R)-5-(4-methoxy-3-propoxyphenyl)-5-methyloxazolidin-2-one · (5R)-5-(4-Methoxy-3-propoxyphenyl)-5-Methyl-2-oxazolidinone
Identifikatoren & physikalische Daten
| CAS No. | 189940-24-7 |
|---|---|
| Summenformel | C14H19NO4 |
| Durchschnittliche Molmasse | 265,3 g/mol |
| Monoisotopische Masse | 265,13140809 g/mol |
| SMILES | CCCOc1cc([C@]2(C)CNC(=O)O2)ccc1OC |
| InChIKey | PCCPERGCFKIYIS-AWEZNQCLSA-N |
| PubChem CID | 449190 |
| ChEMBL | CHEMBL603830 |
| DTXSID | DTXSID001319171 |
Chemische & physikalische Eigenschaften
| XLogP | 2,3 |
|---|---|
| Polarare Oberfläche (TPSA) | 56,8 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 4 |
| Frei drehbare Bindungen | 5 |
| Schwere Atome | 19 |
| Formalladung | 0 |
| Komplexität | 323 |
| Arzneimittel | Pharmaceuticals -> Listed in ZINC15 |
| Endocrine Disruptors | Potential endocrine disrupting compound |
| Siedepunkt | 459.1±45.0 °C(Predicted) |
| Dichte | 1.124±0.06 g/cm3(Predicted) |
| Lagerbedingungen | Store at +4°C |
| Löslichkeit | <26.53mg/ml in DMSO<26.53mg/ml in ethanol |
| pKa (Säurekonstante) | 12.23±0.40(Predicted) |
| Aggregatzustand | Solid |
| Farbe | White to off-white |
Anwendungen & Verwendung
Verwenden
Mesopram is an orally active phosphodiesterase (PDE) 4 inhibitor. Mesopram decreases the synthesis of tumor necrosis factor-α (TNF-α) and interferon-γ (IFN-γ). Mesopram is used in compositions for the treatment or prevention of respiratory inflammation.