3'-Deoxy-3'-fluorouridine
3'-F-3'-dU · CAINDEXNAME · 3'-F-3'-deoxy-uridine · 3'-Fluoro-3'-deoxyuridine · 3’-Deoxy-3’-fluorouridine · 3'-fluoro-3'-desoxyuridine · Uridine, 3'-deoxy-3'-fluoro- · CAINDEXNAME:URIDINE,3'-DEOXY-3'-FLUORO
Identifikatoren & physikalische Daten
| CAS No. | 57944-13-5 |
|---|---|
| Summenformel | C9H11FN2O5 |
| Durchschnittliche Molmasse | 246,19 g/mol |
| Monoisotopische Masse | 246,06519962 g/mol |
| SMILES | O=c1ccn([C@@H]2O[C@H](CO)[C@@H](F)[C@H]2O)c(=O)[nH]1 |
| InChIKey | FVBOTRDLABQYMI-XVFCMESISA-N |
| PubChem CID | 451602 |
| ChEMBL | CHEMBL2311159 |
| DTXSID | DTXSID80206649 |
Chemische & physikalische Eigenschaften
| XLogP | -1,5 |
|---|---|
| Polarare Oberfläche (TPSA) | 99,1 |
| H-Brücken-Donoren | 3 |
| H-Brücken-Akzeptoren | 6 |
| Frei drehbare Bindungen | 2 |
| Schwere Atome | 17 |
| Formalladung | 0 |
| Komplexität | 374 |
| Dichte | 1.63±0.1 g/cm3(Predicted) |
| pKa (Säurekonstante) | 9.39±0.10(Predicted) |
| Aggregatzustand | Solid |
| Farbe | White to off-white |
| InChI | InChI=1S/C9H11FN2O5/c10-6-4(3-13)17-8(7(6)15)12-2-1-5(14)11-9(12)16/h1-2,4,6-8,13,15H,3H2,(H,11,14,16)/t4-,6-,7-,8-/m1/s1 |
| InChIKey | FVBOTRDLABQYMI-XVFCMESISA-N |
| SMILES | OC[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](O)[C@@H]1F |
| CAS Datenbank | 57944-13-5 |
Sicherheit & Vorschriften
| Alarmwort | Warnung |
|---|---|
| Gefahrenhinweise | Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H302 |
Anwendungen & Verwendung
Beschreibung
3′-Deoxy-3′-fluorouridine, a compound of utmost significance in the biomedical industry, assumes a pivotal position in the advancement of antiviral pharmaceuticals targeting RNA virus-associated ailments. This exceptional product showcases its robust antiviral efficacy against a multitude of viruses. Through the powerful mechanism of inhibiting viral replication, 3'-Deoxy-3'-fluorouridine emerges as a propitious contender in the ongoing battle against these formidable infectious maladies.
Verwenden
3''-Deoxy-3''-fluorouridine is a uridine derivative and is useful in the study of E. Coli. Also, a reagent in the design of hepatitis C antviral agents.