N-sulfo-D-glucosamine
Grundinformationen
- CAS
38899-05-7- Standard-SMILES
O=S(=O)(O)N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O- InChIKey
PRDZVHCOEWJPOB-IVMDWMLBSA-N- Summenformel
- C6H13NO8S
- Durchschnittliche Molmasse
- 259,24 g/mol
- Monoisotopische Masse
- 259,03618755
Namen und Bezeichner
- Bevorzugter Name
- N-sulfo-D-glucosamine
- IUPAC
- [(3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]sulfamic acid
- Englischer Name
- N-Sulfo-glucosamine sodium salt
- Summenformel
- C6H14NNaO8S
- Molmasse
- 283.23
Namen und Synonyme
N-sulfo-D-glucosamineCHEBI:167022-deoxy-2-sulfoamino-D-glucopyranoseRefChem:164232GlyTouCan:G41251HAG41251HAGlcNSGlucosamine-2-sulfate2-Deoxy-2-(sulfoamino)-D-glucopyranoseD-Glucosamine-2-sulfateSCHEMBL1542063DTXSID40959664
Weitere Namen anzeigen
D-Glucosamine 2-sufate sodium saltD-GLUCOSAMINE SULFATE SODIUM CHLORIDED-GLUCOSAMINE 2-SULFATE SODIUM SALTD-GLUCOSAMINE 2-SULFATE SODIUMGlcN-2SGLCN-2S, NASODIUMSALT(6CI)glucosaMine sulfate (Na)D-GlucosaMine Sulfate 2KCIGLUCOSAMINE SULFATE (SODIUM)
PRDZVHCOEWJPOB-IVMDWMLBSA-N2-Deoxy-2-(sulfoamino)hexopyranoseBDBM50608272C01075Q27102034[(3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-3-yl]sulfamic acid
Datenbank-Bezeichner
- CAS
38899-05-7- PubChem CID
- 453619
- DTXSID
DTXSID40959664- ChEBI
CHEBI:16702- Nikkaji
- J1.781.278E
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- -2,4
- Polarare Oberfläche (TPSA)
- 165 Ų
- H-Brücken-Donoren
- 6
- H-Brücken-Akzeptoren
- 9
- Frei drehbare Bindungen
- 3
- Schwere Atome
- 16
- Formalladung
- 0
- Komplexität
- 326
Physikochemische Eigenschaften
- storage temp.
- -20 °C · Inert atmosphere,Store in freezer, under -20°C
- Löslichkeit
- Soluble in DMSO
- InChI
- InChI=1/C6H13NO8S.Na.H/c8-1-3(7-16(13,14)15)5(11)6(12)4(10)2-9;;/h1,3-7,9-12H,2H2,(H,13,14,15);;/t3-,4+,5+,6+;;/s3
- InChIKey
- XWFHXUOTHFHRAS-IWNCBHIWNA-N
- SMILES
- [C@@H](C=O)(NS(O)(=O)=O)[C@@H](O)[C@H](O)[C@H](O)CO.[NaH] |&1:0,8,10,12,r|
- CAS Datenbank
- 38899 · 38899-05-7(CAS DataBase Reference)
Sicherheit und Regulatorisches
Sicherheitsdaten
- wgk
- 3
- hs_code
- 29329990
Chemie und Industrie
Anwendungen
BeschreibungN-Sulfo-glucosamine sodium salt is a synthetic, high purity carbohydrate with a custom synthesis. It is an oligosaccharide that is also a sugar and a saccharide. The methylation of it can be achieved by glycosylation or click modification. Click modification is the addition of a carbon atom to the molecule through the reaction with an electrophile, such as N-hydroxysuccinimide ester. This modification can be used to introduce fluorine atoms into the molecules, which can improve their solubility and stability. The product has shown anti-inflammatory activities in animal models, which may be due to its ability to inhibit prostaglandin synthesis.
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