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Diclazuril

HCID 456389
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Grundinformationen

CAS
101831-37-2
Standard-SMILES
N#CC(c1ccc(Cl)cc1)c1c(Cl)cc(-n2ncc(=O)[nH]c2=O)cc1Cl
InChIKey
ZSZFUDFOPOMEET-UHFFFAOYSA-N
Summenformel
C17H9Cl3N4O2
Durchschnittliche Molmasse
407,6 g/mol
Monoisotopische Masse
405,979109

Namen und Bezeichner

Bevorzugter Name
Diclazuril
IUPAC
2-(4-chlorophenyl)-2-[2,6-dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenyl]acetonitrile
Englischer Name
Diclazuril
Summenformel
C17H9Cl3N4O2
Molmasse
407.64

Namen und Synonyme

DICLAZURIL101831-37-2ClinacoxVecoxanNuoqiuDiclazuriloDiclazurilumDTXSID4046787Diclazuril for veterinary useNSC-759642K110K1B1VER64,433
Weitere Namen anzeigen
Diclazuril powderQiujiaR-64433clinazoxiclazurilDICLAZUTIL
P-644332,6-dichloro-alpha-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)benzeneacetonitrileBenzeneacetonitrile, 2,6-dichloro-alpha-(4-chlorophenyl)-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)-DTXCID2026787R-64-433Protazil2,6-Dichloro-alpha-(4-chlorophenyl)-4-[4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl]benzeneacetonitrileClinacox 0.2%

Datenbank-Bezeichner

CAS
101831-37-2
PubChem CID
456389
DTXSID
DTXSID4046787
ChEMBL
CHEMBL284733
ChEBI
CHEBI:95118
UNII
K110K1B1VE
EC Number
640-372-7、692-717-6
Nikkaji
J413.493A

Eigenschaften

Berechnete StruktureigenschaftenWird ergänzt

XLogP
4,1
Polarare Oberfläche (TPSA)
85,6 Ų
H-Brücken-Donoren
1
H-Brücken-Akzeptoren
4
Frei drehbare Bindungen
3
Schwere Atome
26
Formalladung
0
Komplexität
629

Physikochemische Eigenschaften

Schmelzpunkt
290.5 ° · 290.5°
Dichte
1.56 · 1.56±0.1 g/cm3(Predicted)
storage temp.
Inert atmosphere,Room Temperature
Löslichkeit
5 mg/mL; · DMF: 5mg/mL; DMSO: 5mg/mL; DMSO:PBS (pH 7.2) (1:5): 0.16mg/mL
pka
5.89 · 5.89±0.20(Predicted)
Aggregatzustand
Solid
Farbe
White to Light yellow to Light orange
Merck
14 · 14,3080
Major Application
forensics and toxicologypharmaceutical (small molecule)
InChI
InChI=1S/C17H9Cl3N4O2/c18-10-3-1-9(2-4-10)12(7-21)16-13(19)5-11(6-14(16)20)24-17(26)23-15(25)8-22-24/h1-6,8,12H,(H,23,25,26)
InChIKey
ZSZFUDFOPOMEET-UHFFFAOYSA-N
SMILES
C1(C=C(C(C(C#N)C2=CC=C(Cl)C=C2)=C(Cl)C=1)Cl)N1N=CC(=O)NC1=O
LogP
2.439 · 2.439 (est)
CAS Datenbank
101831 · 101831-37-2(CAS DataBase Reference)

Sicherheit und Regulatorisches

Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.

GHS-Klassifizierung

GHS Classification · 6 Einträge

This chemical does not meet GHS hazard criteria for 2.2% (1 of 46) of reports.

Warning

H361 (76.1%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity];H373 (78.3%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure];H400 (19.6%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]

P203, P260, P273, P280, P318, P319, P391, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 46 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 1 of 46 reports by companies.;There are 5 notifications provided by 45 of 46 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Regulatory Information · 2 Einträge

Regulation (EC) No 1831/2003 (amended)

Diclazuril: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazard Classes and Categories · 2 Einträge

Repr. 2 (76.1%);STOT RE 2 (78.3%);Aquatic Acute 1 (19.6%)

Aquatic Acute 1 (100%)

Regulatorische Informationen

Regulatory Information · 2 Einträge

Regulation (EC) No 1831/2003 (amended)

Diclazuril: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Sicherheitsdaten

wgk
2
hs_code
29336990
RTECS-Nr.
CY1697600
safety_code
24/25
Speicherklasse
11 - Combustible Solids
Hazard Classifications
Repr. 2STOT RE 2

Chemie und Industrie

Pharmakologische Informationen

ATC CodeQP - Antiparasitic products, insecticides and repellents;QP51 - Antiprotozoals;QP51B - Agents against coccidiosis;QP51BC - Triazines against coccidiosis;QP51BC03 - Diclazuril
MeSH Pharmacological ClassificationAgents useful in the treatment or prevention of COCCIDIOSIS in man or animals.

Verwendung und Herstellung

Use Classification · 3 Einträge

Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients

Veterinary Drug -> ANTIPROTOZOAL_AGENT -> JECFA Functional Classes

Pharmaceuticals -> Animal Drugs -> Approved in Taiwan

Anwendungen · 1 Eintrag

VerwendenDiclazuril is a triazinone antiprotozoal that Nucleotide analog with broad-spectrum anticoccidial activity. It has a control effect on a variety of coccidiosis, and is used to prevent coccidiosis in chickens, ducks, quails, turkeys, geese and rabbits.

Anbieter100 Anbieter

国药集团化学试剂有限公司86-21-63210123 · [email protected]
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大连美仑生物技术有限公司0411-62910999 13889544652 · [email protected]
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上海钰康生物科技有限公司+86-18930848214 +86-021-56762820 · [email protected]
上海泰坦科技股份有限公司4006009262 13023226327 · [email protected]
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山东捷承制药有限公司0531-83130525 18560095177 · [email protected]
孝感深远化工有限公司15527621225; 15527621225 · [email protected]
云南西力生物技术股份有限公司0871-65217109 · [email protected]
Abblis Chemicals LLC+1-832-373-8299 · [email protected]
北京科富瑞德科技发展有限责任公司+86-010-60279497 +86-15646567669 · [email protected]
四川库利南科技有限公司400-1166-196 18981987031 · [email protected]
上海厚博生物科技有限公司+21-18501659228 18501659228 · [email protected]
上海思域化工科技有限公司86-21-34053660 · [email protected]
上海遐瑞医药科技有限公司+86 21 61551611
TCI AMERICA800-4238616 · [email protected]
TOKYO CHEMICAL INDUSTRY CO., LTD.03-36680489 · [email protected]
TCI Europe320-37350700 · [email protected]
深圳振强药物研发有限公司0755-66853366 13670046396 · [email protected]
广州爱纯医药科技有限公司020-39119399 18927568969 · [email protected]
南京生利德生物科技有限公司025-57798810 18652991625 · [email protected]
湖北鑫源顺医药化工有限公司13971561712, 13995564702, 027-50664929 · [email protected]
上海将来实业股份有限公司400-0066400 13621662912 · [email protected]
HBCChem, Inc.+1-510-219-6317 · [email protected]
上海石洋化工有限公司021-56795766 · [email protected]
四川省维克奇生物科技有限公司028-81700200 18116577057 · [email protected]
雷丁试剂0510-85629785 18013409632 · [email protected]
杭州杰恒化工有限公司0571-87396432 · [email protected]
上海寰川实业有限公司021-61478794 · [email protected]
凯试(上海)科技有限公司021-50135380 · [email protected]
池州凯隆进出口贸易有限公司[email protected]
桦特昇生物科技(武汉)有限公司027-59207879 1972026995 18140587686 · [email protected]
天津阿尔塔科技有限公司022-6537-8550 15522853686 · [email protected]
江苏倍达医药科技有限公司0512-63009836 18994340901 · [email protected]
TargetMol中国(陶术生物)021-021-33632979 15002134094 · [email protected]
湖北康恩化学有限公司180-64105258 18064105258 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
山东济好生物科技有限公司0531-69958659 15668363232 · [email protected]
成都润泽本土化工有限公司028-88469284 18000562381 · [email protected]
南京艾比克斯生化科技有限公司025-87193546 18652950785 · [email protected]
南京熙朗化工产品有限公司18936048580 · [email protected]
北京华威锐科化工科技有限公司89508211 18501085097 · [email protected]
上海西陇生化科技有限公司021-52907766-8042
上海前衍生物科技有限公司02781293128 · [email protected]

Zugehörige Reaktionen

6
Reaktionsaufzeichnung erstellen
Reaktionsgleichung von HRID 35564
HRID 35564als Eduktuspto-grants-1988_08
Reaktionsgleichung von HRID 355362
HRID 355362als Produktuspto-grants-1998_11
Reaktionsgleichung von HRID 950899
HRID 950899als EduktValidation data from https://doi.org/10.1039/C8SC04228D
Reaktionsgleichung von HRID 1140780
HRID 1140780als ProduktTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaktionsgleichung von HRID 1165852
HRID 1165852als Eduktuspto-grants-1990_03
Reaktionsgleichung von HRID 1604320
HRID 1604320als Produktuspto-grants-1999_11

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